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    Plano, TX Medical Office Space for Sale

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    Allen, TX Murphy, TX Frisco, TX
    15 results
    Prime Office and Medical Space
    $595,000
    2.69 Acres
    Prime Office and Medical Space

    5805 Coit Road, Plano, TX 75093

    Turnkey, income-producing asset in a strong Plano submarket.
    • Stable in‑place income with future owner‑user flexibility presents an exceptional investment opportunity.
    • Highly accessible location with immediate connectivity to major highways (Dallas North Tollway, N Central Expwy, Sam Rayburn Turnpike, President George Bush Turnpike).
    • Turnkey, move‑in ready suite with functional double‑wing layout suitable for various professional uses (legal, financial, medical, etc.).
    • Includes welcoming reception area, multiple private offices, open work area, renovated restroom, and fully‑equipped kitchen.
    • Ample surface parking (first‑come, first‑served).
    Updated: Apr 7
    View details
    Freestanding Office Building in Plano
    $700,000
    0.39 Acres
    Freestanding Office Building in Plano

    1225 19th Street, Plano, TX 75074

    Well-maintained office building in Plano, ideal for various uses.
    • Freestanding office building in a desirable Plano location.
    • Approximately 5,075 square feet suitable for medical, professional, or general office use.
    • Convenient access to US‑75, downtown Plano, dining, retail, and public transit.
    • Multiple private offices, open work areas, and a welcoming reception area.
    • Ample on‑site parking.
    Updated: Nov 14, 2025
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    Plano Condo/Medical Office Space
    $895,000
    2,607 SF
    Plano Condo/Medical Office Space

    Condo/Medical office with 7 offices near retail and hospitals.

    5172 Village Creek Drive 102, Plano, TX 75093

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    Move-in Ready Office Near Hospital
    $950,000
    2,536 SF
    Move-in Ready Office Near Hospital

    Turnkey office space near Children’s Hospital, built in 2014.

    7709 San Jacinto Place, Plano, TX

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    Prime Retail Space on Tollway
    $2,500,000
    5,040 SF
    Prime Retail Space on Tollway

    Freestanding building ideal for medical or retail businesses.

    5945 Dallas Parkway 400, Plano, TX 75093

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    Plano Office Space For Sale
    $725,900
    5,421 SF
    Plano Office Space For Sale

    5,421 SF office space ideal for medical or professional users.

    4691 Old Shepard Pl, Plano, TX

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    Medical Office Building For Lease
    Contact for pricing
    5,000 SF
    Medical Office Building For Lease

    Three-story medical office building available for lease.

    3465 National Dr, Plano, TX

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    Plano Commercial Land For Sale
    Contact for pricing
    4,292 SF
    Plano Commercial Land For Sale

    Commercial land suitable for retail, office, and medical use.

    9105 CUSTER ROAD, Plano, TX 75025

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    Prime Land at Preston Road
    Contact for pricing
    4,225 SF
    Prime Land at Preston Road

    Located at a prime intersection, ideal for various commercial uses.

    1517 PRESTON ROAD, Plano, TX 75093

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    Plano Medical Office Space
    Contact for pricing
    19,200 SF
    Plano Medical Office Space

    Fully leased medical office space in Plano, Texas.

    6101 Windcom Court, Plano, TX

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    Texas Oral Health Facility
    $15,069,766
    35,430 SF
    Texas Oral Health Facility

    Fully occupied medical center with diversified income stream.

    5800 Coit Rd, Plano, TX 75023

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    Professional Office Condo Near Highway
    $629,000
    1,577 SF
    Professional Office Condo Near Highway

    Move-in ready office condo with highway access and signage.

    3447 E Renner Rd, Plano, TX

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    New Office Building Near Hospitals
    Contact for pricing
    6,818 SF
    New Office Building Near Hospitals

    Office building near medical facilities with easy highway access.

    4716 Dexter Dr, Plano, TX

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    Modern Office Building in Plano
    $12,096,000
    33,600 SF
    Modern Office Building in Plano

    New construction office building with high visibility in prime location.

    5740 State Hwy 121, Plano, TX

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    Plano Medical Office Investment
    $2,790,000
    7,525 SF
    Plano Medical Office Investment

    100% leased medical office in Plano, Texas.

    4108 W 15th St, Plano, TX 75093

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    Based on your search, we've compiled 43 Potential Opportunities for your consideration. Besides 15 Active listings in Plano, TX, we suggest exploring several alternatives: 4 properties in Nearby Cities, and similar 20 Off-Market properties to explore as potential leads, plus 4 Land Listings that present a potential for development.

    Opportunities in Nearby Cities

    Here are 4 Similar properties we found in Nearby Locations for your consideration.

    Prime Commercial Land in Frisco
    $5,245,000
    2.44 Acres
    Prime Commercial Land in Frisco

    High-visibility land suitable for retail, medical, restaurant, or mixed-use development.

    4400 Preston Road, Frisco, TX 75034

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    Carrollton Medical Office Building For Sale
    $1,700,000
    5,005 SF
    Carrollton Medical Office Building For Sale

    Move-in-ready medical office building in a desirable professional park.

    4100 Fairway Court, Carrollton, TX 75010

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    Modern Office Condo in Carrollton
    Contact for pricing
    1,228 SF
    Modern Office Condo in Carrollton

    Well-designed office space in a vibrant Carrollton location.

    4425 Plano Parkway #702, Carrollton, TX 75010

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    Frisco Commercial Opportunity on Preston
    $5,245,000
    13,932 SF
    Frisco Commercial Opportunity on Preston

    High-visibility commercial land near PGA Headquarters in Frisco, Texas.

    4400 Preston Road, Frisco, TX 75034

    View details

    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

    Commercial Land in Central Plano
    $350,000
    0.43 Acres
    Commercial Land in Central Plano

    0.43 acre commercial plot in central Plano, Texas.

    Unknown Silverstone Drive, Plano, TX 75023

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    Vacant Commercial Lot in Plano
    $950,000
    1.05 Acres
    Vacant Commercial Lot in Plano

    Commercial lot in high-growth market with excellent accessibility and visibility.

    3320 Premier Drive, Plano, TX 75023

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    Frisco Land Ready for Development
    $999,990
    1.00 Acre
    Frisco Land Ready for Development

    Prime Frisco land with approved plans and utilities in place.

    7311 Rolling Brook Drive, Frisco, TX 75034

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    Prime Frisco Development Opportunity
    $2,600,000
    2.00 Acres
    Prime Frisco Development Opportunity

    2-acre development site in North Frisco Commercial Corridor.

    13150 Preston Rd, Frisco, TX 75035

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    Off-Market Properties in Plano, TX

    Consider similar Off-Market properties in Plano, TX. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

    4712 Dexter Dr

    4712 Dexter Dr

    Medical Office Space
    Value Estimation by Request
    4712 Dexter Dr, Plano, TX 75093
    View details
    4065 Plano Pkwy

    4065 Plano Pkwy

    Medical Office Space • 35,000 SF
    Value Estimation by Request
    4065 Plano Pkwy, Plano, TX 75074
    View details
    3447 Renner Rd

    3447 Renner Rd

    Medical Office Space • 1,800 SF
    Value Estimation by Request
    3447 Renner Rd, Plano, TX 75074
    View details
    5085 Park Blvd

    5085 Park Blvd

    Medical Office Space • 84,825 SF
    Value Estimation by Request
    5085 Park Blvd, Plano, TX 75093
    View details
    6541 Preston Rd

    6541 Preston Rd

    Medical Office Space • 1,497 SF
    Value Estimation by Request
    6541 Preston Rd, Plano, TX 75024
    View details
    1200 Coit Rd

    1200 Coit Rd

    Medical Office Space • 3,058 SF
    Value Estimation by Request
    1200 Coit Rd, Plano, TX 75075
    View details
    6513 Preston Rd

    6513 Preston Rd

    Medical Office Space • 2,978 SF
    Value Estimation by Request
    6513 Preston Rd, Plano, TX 75024
    View details
    7924 Preston Rd

    7924 Preston Rd

    Medical Office Space • 25,245 SF
    Value Estimation by Request
    7924 Preston Rd, Plano, TX 75024
    View details
    4200 Mapleshade Ln

    4200 Mapleshade Ln

    Medical Office Space • 2,500 SF
    Value Estimation by Request
    4200 Mapleshade Ln, Plano, TX 75093
    View details

    Plano, TX Medical Office Space Investment Opportunities Market Analysis

    Explore 35 medical office space for sale in Plano, TX, showcased through 15 active listings on our real estate platform. These investment opportunities span a total of 93,736 square feet of properties for sale, with an estimated market value of $35,655,666.

    Sale prices for medical spaces in Plano, TX start at $629,000, averaging $4,456,958, and reaching up to $15,069,766 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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    6-Month New Listing Trend

    Monthly new listing volume vs. 6-month average in Plano.

    Top Commercial Asset Segments

    Office Units 173
    Medical Office Space 45
    Office buildings 40
    Serviced offices 13
    Coworking space 11

    Property Size Breakdown

    The majority of commercial real estate listings in Plano fall within the 100,000+ square foot range.

    Demographics Overview

    Population 309K
    Population Growth (5Y) +1.2%
    Median Household Income $113,836
    College Educated 64.4%

    High-Yield Neighborhoods for Strategic Investment

    Identify Plano submarkets with the highest inventory density on the market and evaluate the median listing prices of real estate assets

    Neighborhood Average Price
    75074 $700K
    75093 $1.7M
    75023 $15.1M

    Taxes & Financing

    Tax Rate (average for all types) 1.73%
    Property Tax per SF $18.02 per sq ft
    Tax Rate vs County Average 0.01 pp below county avg
    Average Loan-to-Value 65.0%

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