Spring, TX Medical Office Space for Rent & Lease

Updated: Sep 25, 2025

Retail/Medical Office Space Available

18551 Champion Forest Drive, Spring, TX 77379

$360/Mo

2,550 sqft

Prime location at the entrance of the prestigious Gleannloch Farms community.
Excellent visibility.
Strong median household income of $166,373.
5,131 SF of retail/medical office space.**
Ample parking.

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Updated: Jul 1

Flexible Shell Retail Building

26214 Interstate 45 N, Spring, TX 77386

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20,000 sqft

20,000 SF shell retail building built in 2017
Open floor plan designed to be customized for multiple commercial concepts
Suitable for retail, medical, restaurant, fitness, office, or professional service uses

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White-Box Retail Suite

26830 Cypresswood Drive, Spring, TX 77373

$27 SF/Yr

Brand new, move-in-ready retail suite with a flexible open plan and dedicated parking field.

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Class A Medical Office Building

21848 Holzwarth Road, Spring, TX 77388

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11,598 sqft

Three-story medical office building in Spring, Texas, near major highways.

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Air-Conditioned Flex Space

23855 Gosling Rd, Spring, TX 77389

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10,000 sqft

Adaptable commercial layout with conditioned space and positioning for office or medical use.

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Medical Space in The Woodlands

4185 Technology Forest Blvd, Spring, TX

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7,377 sqft 3.80 AC lot

Second generation medical space available in The Woodlands, Texas.

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Corner Office Unit

5515 Louetta Rd Suite C, Spring, TX 77379

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Professional suite with private offices, a kitchenette, ADA-compliant bathroom, natural light, and lake views.

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Medical Office Space Available

129 Vision Park Boulevard, Spring, TX

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2,694 sqft 4.48 AC lot

Medical office space for rent near major hospitals.

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Professional Medical Office Buildings

21927 Gosling Road, Spring, TX 77388

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5,587 sqft

Two-build office complex with two-story plans and delivered 400-amp electrical service available for sale or lease.

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Two-Story Medical Office Buildings

21919 Gosling Road, Spring, TX 77388

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5,587 sqft

Two professional office buildings in a new office complex, with build-to-suit options and frontage along Gosling Road.

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Based on your search, we've compiled 19 Potential Opportunities for your consideration. Besides 10 Active listings in Spring, TX, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities, and Similar 5 Properties for Sales.

Medical Office Space for Lease in Nearby Cities

Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

FM 1960 Medical/Office Space

2010 FM 1960 RD, Houston, TX

Contact for pricing

7,700 sqft 2.54 AC lot

5,000 SF raw space for medical or office use.

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Class A Medical Office Building

8850 Six Pines Drive, The Woodlands, TX 77380

Contact for pricing

Two-story medical office building near major hospitals with convenient access.

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Former Pediatric Clinic Available

4560 W FM 1960 RD, Houston, TX

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2,450 sqft 1.43 AC lot

Former pediatric clinic with multiple exam rooms and restrooms.

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The Woodlands Office/Medical Space

200 Valleywood Rd, The Woodlands, TX 77380

Contact for pricing

39,581 sqft 2.56 AC lot

Premier office/medical space in The Woodlands, immediate access to I-45.

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Similar Spaces for Sale in Spring, TX

Consider Similar Space for Sale. We found 5 Spaces matching your search parameters.

Vacant Medical Office with Dental Build-Out

25412 Interstate 45, Spring, TX 77386

Contact for pricing

2,760 sqft

Purpose-built clinical space is delivered vacant with dental infrastructure in place.

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Spring Cypress Freestanding Buildings

6710 Spring Cypress Rd, Spring, TX

Contact for pricing

5,689 sqft 1.55 AC lot

Freestanding buildings ideal for office, medical, retail, or services.

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Spacious Medical Center with Financing

26407 Oak Ridge Dr, Spring, TX 77380

Contact for pricing

7,688 sqft

Large medical center with owner financing in The Woodlands.

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Two-Story Medical Office Buildings

21919 Gosling Road, Spring, TX 77388

Contact for pricing

5,587 sqft

Two professional office buildings with build-to-suit options and about 165 feet of frontage on Gosling Road.

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Medical/Professional Building For Sale

21927 Gosling Rd, Spring, TX 77388

Contact for pricing

5,587 sqft

5,587 SF medical/professional building available for purchase.

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Spring, TX Medical Office Space Lease Rates & Market Statistics

Explore 10 Medical Office Space listings for lease in Spring, TX on Realmo, a commercial real estate exchange covering the Spring area. The current inventory totals 65,393 square feet of properties — an average of ~6,550 SF per listing.

Asking lease rates for Medical Office Space in Spring start at $1.69 SF/Yr, average $14.35 SF/Yr, and reach $27 SF/Yr at the top of the market. That's a 16x spread between entry-level and premium space, making side-by-side comparison of asking rents and lease terms essential. The local average of $14.35 SF/Yr is 41% below the Texas state average of $24.22 SF/Yr.

Spring accounts for 13% of the 75 medical office space listings currently available across Harris County, where nearby markets include Houston and Cypress. Medical Office Space listings make up 21% of the 48 Office Spaces currently for lease in Spring, with asking rates averaging $14.35 SF/Yr — 72% below the citywide Office Spaces average of $52.03 SF/Yr. Also worth a look for tenants weighing alternatives: Office Units (29 listings) and Office buildings (10 listings) elsewhere in the Spring market.