Spring, TX Medical Office Space for Rent & Lease

Updated: Sep 25, 2025

Retail/Medical Office Space Available

18551 Champion Forest Drive, Spring, TX 77379

$360/Mo

2,550 sqft

Prime location at the entrance of the prestigious Gleannloch Farms community.
Excellent visibility.
Strong median household income of $166,373.
5,131 SF of retail/medical office space.**
Ample parking.

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Updated: May 6

Single-Story Medical Office Facility

17810 Spring Creek Forest Drive, Spring, TX 77379

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14,746 sqft 5.00 AC lot

Single‑story commercial building built in 1986 with 14,746 SF of interior space on 5.00 acres
Includes 25 private rooms/offices plus a dedicated laundry room and cafeteria/break room area
Four multi‑stall restrooms and three additional private bathrooms for flexible workspace needs
Approx. 24,000 SF of concrete exterior surface, gated entrance, and walking path
50+ total parking spaces including 2 ADA‑compliant spots

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Shopping Center with Interstate Frontage

26214 Interstate 45 N, Spring, TX 77386

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20,000 sqft

Flexible retail and medical space with extensive parking, prominent signage opportunities, and access to major regional routes.

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White-Box Retail Suite

26830 Cypresswood Drive, Spring, TX 77373

$27 SF/Yr

Brand new, move-in-ready retail suite with a flexible open plan and dedicated parking field.

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Class A Medical Office Building

21848 Holzwarth Road, Spring, TX 77388

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11,598 sqft

Premier medical office building in Spring, Texas, with high-end finishes.

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Multi-Tenant Medical Office Building

8111 Cypresswood Drive, Spring, TX 77379

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3,436 sqft

Well-maintained multi-tenant medical and professional building offering flexible suites and prominent signage with ample surface parking.

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Flexible Shell Retail Building

26214 Interstate 45, Spring, TX 77386

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20,000 sqft

Newer shell retail space with an open floor plan that can be customized for multiple commercial concepts.

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Air-Conditioned Flex Space

23855 Gosling Rd, Spring, TX 77389

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10,000 sqft

Adaptable commercial layout with conditioned space and positioning for office or medical use.

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Medical Office Space Available

129 Vision Park Boulevard, Spring, TX

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2,694 sqft 4.48 AC lot

Medical office space for rent near major hospitals.

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Cypresswood Drive Office Space Available

8111 Cypresswood Dr, Spring, TX 77379

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Multi-tenant medical and professional office building with flexible suite sizes.

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The Woodlands Office Space Available

2490 FM 2920, Spring, TX

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20,921 sqft 1.87 AC lot

Medical and professional office space for lease in Spring, TX.

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Professional Medical Office Buildings

21927 Gosling Road, Spring, TX 77388

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5,587 sqft

Two-build office complex with two-story plans and delivered 400-amp electrical service available for sale or lease.

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Two-Story Medical Office Buildings

21919 Gosling Road, Spring, TX 77388

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5,587 sqft

Two professional office buildings in a new office complex, with build-to-suit options and frontage along Gosling Road.

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Medical Space in The Woodlands

4185 Technology Forest Blvd, Spring, TX

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7,377 sqft 3.80 AC lot

Second generation medical space available in The Woodlands, Texas.

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Class A Medical Office Building

21848 Holzwarth Rd, Spring, TX 77388

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Three-story medical office building in Spring, Texas, near major highways.

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Retail/Medical Office Space Available

18551 Champion Forest Dr, Spring, TX 77379

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5,131 sqft

5,131 SF retail/medical space near Grand Parkway in Spring, TX.

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Medical & Professional Office Space

2490 Farm to Market 2920, Spring, TX 77388

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Available office space in The Woodlands submarket.

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Based on your search, we've compiled 23 Potential Opportunities for your consideration. Besides 17 Active listings in Spring, TX, we suggest exploring alternatives. Similar 6 Properties for Sales.

Similar Spaces for Sale in Spring, TX

Consider Similar Space for Sale. We found 6 Spaces matching your search parameters.

Spring Cypress Freestanding Buildings

6710 Spring Cypress Rd, Spring, TX

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5,689 sqft 1.55 AC lot

Freestanding buildings ideal for office, medical, retail, or services.

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Two-Story Office Building

8500 Cypresswood Drive, Spring, TX 77379

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29,703 sqft 1.95 AC lot

Class B+ office property with reflective glass construction and surface parking near retail, dining, and fitness amenities.

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Upgraded Office Condominium in Spring

5507 Louetta Rd, Spring, TX 77379

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Professional office space with upgrades near The Woodlands and IAH.

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Spacious Medical Center with Financing

26407 Oak Ridge Dr, Spring, TX 77380

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7,688 sqft

Large medical center with owner financing in The Woodlands.

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Two-Story Medical Office Buildings

21919 Gosling Road, Spring, TX 77388

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5,587 sqft

Two professional office buildings with build-to-suit options and about 165 feet of frontage on Gosling Road.

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Medical/Professional Building For Sale

21927 Gosling Rd, Spring, TX 77388

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5,587 sqft

5,587 SF medical/professional building available for purchase.

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Spring, TX Medical Office Space Lease Rates & Market Statistics

Explore 17 Medical Office Space listings for lease in Spring, TX on Realmo, a commercial real estate exchange covering the Spring area. The current inventory totals 129,627 square feet of properties — an average of ~7,650 SF per listing.

Asking lease rates for Medical Office Space in Spring start at $1.69 SF/Yr, average $14.35 SF/Yr, and reach $27 SF/Yr at the top of the market. That's a 16x spread between entry-level and premium space, making side-by-side comparison of asking rents and lease terms essential. The local average of $14.35 SF/Yr is 38% below the Texas state average of $23.24 SF/Yr.

Spring accounts for 12% of the 145 medical office space listings currently available across Harris County, where nearby markets include Houston and Cypress. Medical Office Space listings make up 21% of the 82 Office Spaces currently for lease in Spring, with asking rates averaging $14.35 SF/Yr — 72% below the citywide Office Spaces average of $52.03 SF/Yr. Also worth a look for tenants weighing alternatives: Office Units (51 listings) and Office buildings (17 listings) elsewhere in the Spring market.