Medical Space

Southlake, TX Medical Office Space for Lease

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11 properties
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Medical/Physical Therapy Space Available
Updated: Nov 26, 2025
Medical/Physical Therapy Space Available

1220 N Kimball Ave, Southlake, TX 76092

$21 SF/Yr
7,047 sqft
Built‑out Medical/Physical Therapy Space
Convenient Location: Faces Kimball Ave, near Hwy 114 & DFW Airport
Ample Parking
Sublease Available: 2,824 SF
Sublease Term: 11/1/25 through 11/30/2030
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Newly Constructed Medical Office Space
Updated: Jun 18
Newly Constructed Medical Office Space

731 Zena Rucker Rd, Southlake, TX 76092

Contact for pricing
11,181 sqft
Newly constructed modern office and medical space
22,581 SF of versatile commercial space
Designed for office and medical use
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Class A Medical Office Space
Class A Medical Office Space

731 E Southlake Blvd, Southlake, TX 76092

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13,827 sqft

Class A medical office space with a large contiguous layout, 2nd generation configuration, and signage opportunities.

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Move-In Ready Office Suite
Move-In Ready Office Suite

2111 Kirkwood Blvd., Southlake, TX 76092

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2,020 sqft

Premium office/medical suite is fully built out with high-end finishes, including granite countertops and tile and wood flooring.

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Tower Plaza Medical Office Space
Tower Plaza Medical Office Space

925 E Southlake Blvd, Southlake, TX 76092

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1,145 sqft

Lease availability at a named medical center on East Southlake Boulevard in Southlake, Texas.

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Medical Office Suite
Medical Office Suite

2915 E Southlake Blvd, Southlake, TX 76092

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2,635 sqft

Medical office suite features six treatment rooms, reception and waiting area, patient restrooms, and private consultation space.

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New Medical Office Building
New Medical Office Building

731 Zena Rucker Rd, Southlake, TX 76092

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Newly constructed 2025 modern building suited for office and medical users in Southlake.

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Flex Space With Warehouse
Flex Space With Warehouse

405 S. Nolen Drive, Southlake, TX 76092

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Office, medical, and showroom configurations combine with rear warehouse space and immediate occupancy.

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Class A Medical Office Sublease
Class A Medical Office Sublease

245 W State Highway 114, Southlake, TX 76092

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2,095 sqft

2,095 SF Class A medical office sublease with 40 months remaining on the underlying lease.

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Move-In Ready Medical Office Space
Move-In Ready Medical Office Space

2813 W Southlake Blvd, Southlake, TX

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1,545 sqft 3.05 AC lot

Turnkey medical office space with building signage and ample parking.

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Medical Office Space with Monument Signage
Medical Office Space with Monument Signage

2560 E State Hwy 114, Southlake, TX 76092

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9,400 sqft

New medical office construction supports shell or turnkey delivery along SH 114 in Southlake.

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Based on your search, we've compiled 29 Potential Opportunities for your consideration. Besides 11 Active listings in Southlake, TX, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities, and Similar 14 Properties for Sales.

Medical Office Space for Lease in Nearby Cities

Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

Furnished Medical Office Space
Furnished Medical Office Space

2321 Ira E Woods Avenue Suite 120, Grapevine, TX 76051

$21 SF/Yr
11,090 sqft

Fully equipped clinical workspace with treatment beds, furnishings, and medical equipment in a professional medical park.

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Hurst Medical Office Space
Hurst Medical Office Space

466 MID CITIES BLVD, Hurst, TX 76054

Contact for pricing
3,762 sqft

Medical office space with high visibility and accessibility in Hurst.

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Medical Office Suite with Signage
Medical Office Suite with Signage

2321 Ira E. Woods, Grapevine, TX 76051

Contact for pricing

Medical-oriented office space suited for a primary or secondary practice with reconfiguration options.

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Divisible Medical Office Space
Divisible Medical Office Space

458 Mid Cities Blvd, Hurst, TX 76054

Contact for pricing
7,628 sqft 0.47 AC lot

Divisible medical office space with a spacious waiting area and 24 parking spaces.

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Similar Spaces for Sale in Southlake, TX

Consider Similar Space for Sale. We found 14 Spaces matching your search parameters.

Medical Office Development
Medical Office Development

731 Zena Rucker Road, Southlake, TX 76092

$2,310,000
6,000 sqft 2.25 AC lot

Two-building medical office project under construction with central heating and cooling systems.

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Medical Office Space
Medical Office Space

731 Zena Rucker Road Unit B, B, Southlake, TX 76092

$2,310,000
6,000 sqft

Scheduled medical office development near retail destinations and an elementary school.

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Class A Medical Office Development
Class A Medical Office Development

731 Zena Rucker Road E, Southlake, TX 76092

$640,000
11,400 sqft

Two-building Class A medical development with suite sizes from 2,900 to 11,400 sf, delivering Spring 2025.

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Class A Medical Office Development
Class A Medical Office Development

731 Zena Rucker Road # A, Southlake, TX 76092

$4,370,000
11,400 sqft

Two-building Class A medical development with suites ranging from 2,900 to 11,400 sf, delivering Spring 2025.

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Medical Office Development
Medical Office Development

731 Zena Rucker Road D, Southlake, TX 76092

$1,185,000
3,000 sqft

New medical office space next to Rockenbaugh Elementary School and near three Southlake shopping destinations.

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Two-Building Medical Office Development
Two-Building Medical Office Development

731 Zena Rucker Road, Southlake, TX 76092

$1,755,000
2.25 AC lot

Class A medical project under construction near established Southlake retail destinations and an elementary school.

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Updated Multi-Tenant Office Building
Updated Multi-Tenant Office Building

515 W Southlake Boulevard, Southlake, TX 76092

$4,300,000
2.89 AC lot

Flexible office property with medical and professional office zoning, monument signage, parking, and a dedicated owner-user suite.

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Two-Building Medical Office Development
Two-Building Medical Office Development

731 Zena Rucker Road, Southlake, TX 76092

$640,000
2.25 AC lot

Under-construction project offers medical office suites near Park Village, Shops of Southlake, and Southlake Town Square.

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Two-Building Medical Office Development
Two-Building Medical Office Development

731 Zena Rucker Road, Southlake, TX 76092

$1,185,000
2.25 AC lot

Under-construction medical offices offer flexible configurations with central heating and cooling systems.

View details
Two-Building Medical Office Development
Two-Building Medical Office Development

731 Zena Rucker Road, Southlake, TX 76092

$4,370,000
2.25 AC lot

Under-construction medical space offers multiple suite sizes and walkable access to established Southlake retail destinations.

View details
Two-Building Medical Office Development
Two-Building Medical Office Development

731 Zena Rucker Road Unit D, D, Southlake, TX 76092

$1,185,000

Planned suites offer walkable access to Park Village, Shops of Southlake, and Southlake Town Square.

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Class A Medical Development
Class A Medical Development

731 Zena Rucker Road C, Southlake, TX 76092

$1,755,000

Two-building medical development with suites available from 2,900 to 11,400 sf, delivering Spring 2025.

View details
Two-Building Medical Office Development
Two-Building Medical Office Development

731 Zena Rucker Road Unit A, A, Southlake, TX 76092

$4,370,000

New medical office space is planned near established Southlake retail destinations and an elementary school.

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Southlake, TX Medical Office Space Lease Rates & Market Statistics

Explore 11 Medical Office Space listings for lease in Southlake, TX on Realmo, a commercial real estate exchange covering the Southlake area. The current inventory totals 50,895 square feet of properties — an average of ~4,650 SF per listing.

Medical Office Space lease rates in Southlake range from $21 SF/Yr at the entry level to $21 SF/Yr at the top of the market, averaging $21 SF/Yr. Pricing across the market is relatively uniform, which simplifies like-for-like comparison between listings. At $21 SF/Yr, the local average runs 13% below Texas's state average of $24.16 SF/Yr.

Southlake accounts for 9% of the 121 medical office space listings currently available across Tarrant County, where nearby markets include Fort Worth and Arlington. Medical Office Space listings make up 18% of the 60 Office Spaces currently for lease in Southlake, with asking rates averaging $21 SF/Yr — 14% below the citywide Office Spaces average of $24.50 SF/Yr. Tenants comparing options may also consider Office Units (42 listings) and Office buildings (9 listings) elsewhere in the Southlake market.

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