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    Southlake, TX Medical Office Space for Lease

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    Grapevine, TX Colleyville, TX Dallas, TX
    14 listings
    Professional Office Suite
    $23 SF/Yr
    Professional Office Suite

    325 Miron Drive, Southlake, TX 76092

    Flexible office suite suited for either office or medical use, with convenient access and ample parking.
    • Professional office suite for lease in Southlake, Suite #120: 1,000 SF (per listing).
    • Building built in 1998 with brick and stucco construction and a composition roof.
    • Central heating and central air conditioning throughout the suite.
    • Parking lot on‑site with accessible approach featuring a ramp.
    • Public water and public sewer connected.
    Updated: Feb 26
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    Medical/Physical Therapy Space Available
    $21 SF/Yr
    7,047 SF
    Medical/Physical Therapy Space Available

    1220 N Kimball Ave, Southlake, TX 76092

    Sublease available in Southlake near Hwy 114 & DFW Airport.
    • Built‑out Medical/Physical Therapy Space
    • Convenient Location: Faces Kimball Ave, near Hwy 114 & DFW Airport
    • Ample Parking
    • Sublease Available: 2,824 SF
    • Sublease Term: 11/1/25 through 11/30/2030
    Updated: Nov 26, 2025
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    Southlake Office Suite Available
    $23 SF/Yr
    1,000 SF
    Southlake Office Suite Available

    Professional office suite for lease in Southlake, Texas.

    325 Miron Drive, Southlake, TX 76092

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    Class A Medical Office Suite
    Contact for pricing
    13,827 SF
    Class A Medical Office Suite

    Large contiguous medical space with tenant improvement allowance and visibility for established or growing practices.

    731 E Southlake Blvd, Southlake, TX 76092

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    Medical Office Space For Rent
    Contact for pricing
    2,040 SF
    Medical Office Space For Rent

    Office space connected to Texas Health Harris Methodist Hospital Southlake.

    1545 E Southlake Boulevard, Southlake, TX

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    Move-In Ready Medical Office Space
    $24 SF/Yr
    1,545 SF
    Move-In Ready Medical Office Space

    Turnkey medical office space with building signage and ample parking.

    2813 W Southlake Blvd, Southlake, TX

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    Southlake Medical Office Space Available
    Contact for pricing
    5,263 SF
    Southlake Medical Office Space Available

    Class A medical office space in Southlake, Texas for rent.

    431 E State Highway 114, Southlake, TX

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    Southlake Medical Office Space Available
    Contact for pricing
    2,942 SF
    Southlake Medical Office Space Available

    Class A medical office space with signage available for lease.

    731 E Southlake Blvd, Southlake, TX

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    Southlake Medical/Office Condo Available
    Contact for pricing
    3,205 SF
    Southlake Medical/Office Condo Available

    Medical/office condo with signage and tenant improvement allowance in Southlake.

    3065 W Southlake Blvd, Southlake, TX

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    Southlake Medical/Office Condo Available
    Contact for pricing
    2,914 SF
    Southlake Medical/Office Condo Available

    Medical/Office condo with signage and tenant improvement allowance.

    3055 W Southlake Blvd, Southlake, TX

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    Southlake Medical Office Space Available
    $28 SF/Yr
    Southlake Medical Office Space Available

    Class A medical office space in thriving Southlake, Texas.

    245 W State Hwy 114, Southlake, TX 76092

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    Medical/Office Space Near Southlake Blvd
    Contact for pricing
    Medical/Office Space Near Southlake Blvd

    Medical/office space near shopping and residential areas.

    1100 E Southlake Blvd, Southlake, TX 76092

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    Southlake Office Space For Sublease
    Contact for pricing
    8,052 SF
    Southlake Office Space For Sublease

    Former dental office with highway exposure and ample parking.

    2600 E State 114 Hwy, Southlake, TX

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    Move-In Ready Office Space Available
    $19 SF/Yr
    2,080 SF
    Move-In Ready Office Space Available

    Professional/Medical office space available for lease, move-in ready.

    2485 E Southlake Blvd, Southlake, TX

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    Based on your search, we've compiled 30 Potential Opportunities for your consideration. Besides 14 Active listings in Southlake, TX, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities, and Similar 8 Properties for Sales.

    Medical Office Space for Lease in Nearby Cities

    Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

    Move-in Ready Medical Office Space
    $24 SF/Yr
    2,482 SF
    Move-in Ready Medical Office Space

    Furnished medical office space ready for immediate operation.

    2321 Ira E Woods Avenue #Suite 120, Grapevine, TX 76051

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    Colleyville Office/Medical Suites Available
    $18 SF/Yr
    5,683 SF
    Colleyville Office/Medical Suites Available

    Move-in ready office/medical suites with signage and tenant improvement allowance.

    6221 Colleyville Blvd, Colleyville, TX

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    Move-In Ready Office/Medical Suites
    $18 SF/Yr
    3,885 SF
    Move-In Ready Office/Medical Suites

    Second-generation office/medical suites with tenant improvement allowance.

    6211 Colleyville Blvd, Colleyville, TX

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    Grapevine Office and Medical Complex
    $22 SF/Yr
    Grapevine Office and Medical Complex

    Move-in-ready suites in a thriving Dallas-Fort Worth Metroplex location.

    2301-2331 Mustang Dr, Grapevine, TX 76051

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    Similar Spaces for Sale in Southlake, TX

    Consider Similar Space for Sale. We found 8 Spaces matching your search parameters.

    Class A Medical Office Development
    $2,310,000
    6,000 SF
    Class A Medical Office Development

    Class A two-building medical development with flexible suite sizes, delivering Spring 2025 in Southlake.

    731 Zena Rucker Road, Southlake, TX 76092

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    Class A Medical Office Development
    $1,755,000
    2.25 Acres
    Class A Medical Office Development

    Two-building medical campus delivering Spring 2025 with suites from 2,900 to 11,400 sf.

    731 Zena Rucker Road, Southlake, TX 76092

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    Class A Medical Office Development
    $640,000
    2.25 Acres
    Class A Medical Office Development

    New Spring 2025 medical office project with two buildings and multiple suite sizes for physician and clinic users.

    731 Zena Rucker Road, Southlake, TX 76092

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    Class A Medical Office Development
    $1,185,000
    2.25 Acres
    Class A Medical Office Development

    Two-building Class A medical development delivers Spring 2025 with space options designed for healthcare tenants.

    731 Zena Rucker Road, Southlake, TX 76092

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    Class A Medical Office Development
    $4,370,000
    2.25 Acres
    Class A Medical Office Development

    Two-building, Class A medical development delivering Spring 2025 with flexible suite sizes for healthcare users.

    731 Zena Rucker Road, Southlake, TX 76092

    View details
    Class A Medical Development
    $2,310,000
    6,000 SF
    Class A Medical Development

    Medical office space for sale, delivering Spring 2025.

    731 Zena Rucker Road #B, Southlake, TX 76092

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    Medical Office Portfolio in Southlake
    Contact for pricing
    9,400 SF
    Medical Office Portfolio in Southlake

    Six-building medical office portfolio with high visibility in Southlake, TX.

    2520 E State Hwy 114, Southlake, TX

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    Southlake Medical Office Portfolio
    Contact for pricing
    9,400 SF
    Southlake Medical Office Portfolio

    Medical office space for lease in Southlake, Texas.

    2560 E State Hwy 114, Southlake, TX

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    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

    Office Development Land For Lease
    Contact for pricing
    4,000 SF
    Office Development Land For Lease

    2.43 acres for office development with build-to-suit opportunity.

    1323 Strawfloor Drive, Jonesboro, AR 72401

    View details
    Commercial Land for Long-Term Lease
    $5,950/Mo
    Commercial Land for Long-Term Lease

    Lease a C4-zoned lot with easy interstate access, suited for a range of business and professional uses.

    5538 E Paisano Drive, El Paso, TX 79905

    View details
    Corner Lot on Highway 72
    $5,000/Mo
    1,875 SF
    Corner Lot on Highway 72

    1.7 acre corner lot zoned for commercial, medical, residential.

    30472 Highway 72, Madison, AL 35756

    View details
    Grand Junction Commercial Land Lease
    $9,656/Mo
    Grand Junction Commercial Land Lease

    0.74 acre commercial land for lease in Grand Junction.

    Highway 6&50, Grand Junction, CO 81505

    View details

    Southlake, TX Medical Office Space Market Trends and Statistics

    Explore Medical Office Space leasing options in Southlake, TX with 14 listings featured on our commercial real estate exchange. The current inventory includes 11,672 square feet of properties with an estimated lease value of $87 SF/Yr.

    Estimated lease rates for Medical Office Space in Southlake, TX begin at $19 SF/Yr, with an average of $21 SF/Yr and extend to $24 SF/Yr.
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