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    Daniel Island, SC
    Medical Space

    Daniel Island, SC Medical Office Space for Lease

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    Wando, SC Mount Pleasant, SC North Charleston, SC Hanahan, SC Goose Creek, SC Summerville, SC Ladson, SC Moncks Corner, SC
    7 properties
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    Renovating Office Park Suites
    Updated: Jun 1
    Renovating Office Park Suites

    15 Gamecock Ave, Charleston, SC 29407

    $2,500/Mo
    3,625 sqft
    Two office suites available in Orange Grove Office Park: Unit 1A (+/-720 SF) and Unit B (+/-3,625 SF).
    Unit 1A listed at $2,500/month; Unit B listed at $28/SF on a NNN basis.
    Ongoing renovations at the office park.
    Located in Charleston’s West Ashley submarket within Orange Grove Office Park, just off Sam Rittenberg.
    Immediate access to I‑26; minutes to Downtown Charleston and Charleston International Airport.
    View details
    Single-Story Office Building
    Updated: Jun 2
    Single-Story Office Building

    255 East Bay Street, Charleston, SC 29401

    $35 SF/Yr
    4,730 sqft
    4,730 SF single‑story office building in City of Charleston’s GB (General Business) zoning
    Currently leased to Roper Physician Partners; tenant will vacate with notice
    6 parking spaces included with the lease; 19 marked spaces in front, 2 marked spaces on Pinckney St, and 2 unmarked spaces in the rear
    Landlord will consider leasing “as is,” long‑term ground lease, and redevelopment
    Lease rate listed at $35/SF NNN
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    Two-Story Freestanding Office Building
    Two-Story Freestanding Office Building

    2125 Charlie Hall Blvd, Charleston, SC 29414

    Contact for pricing
    13,113 sqft

    Entire first floor is available in a centrally located, medically oriented freestanding office building with ample parking.

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    Freestanding Medical Office Space
    Freestanding Medical Office Space

    159 Wentworth Street, Charleston, SC 29401

    Contact for pricing

    First-floor layout includes reception, private offices, and exam rooms.

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    Fitness and Chiropractic Sublease Space
    Fitness and Chiropractic Sublease Space

    1291 Folly Rd, Charleston, SC 29412

    Contact for pricing
    5,650 sqft

    Sublease 1,130± SF within Gold’s Gym, with a former cafe space and a chiropractic suite offering private offices.

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    West Ashley Medical Office Sublease
    West Ashley Medical Office Sublease

    2270 Ashley Crossing Ln, Charleston, SC

    Contact for pricing
    3,746 sqft 8.99 AC lot

    3,746 SF medical office space available for immediate sublease.

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    Remodeled Office Space Available
    Remodeled Office Space Available

    1483 Tobias Gadson Blvd, Charleston, SC

    Contact for pricing
    1,312 sqft 6.17 AC lot

    Centrally located office suites near St. Francis Hospital.

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    Based on your search, we've compiled 12 Potential Opportunities for your consideration. Besides 7 Active listings in Daniel Island, SC, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities, and Similar 1 Properties for Sales.

    Medical Office Space for Lease in Nearby Cities

    Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

    Medical Office Space with Clinical Upfit
    Medical Office Space with Clinical Upfit

    2320 Cosgrove Avenue, North Charleston, SC 29405

    $24 SF/Yr
    4,935 sqft 0.31 AC lot

    Plumbing and medical connections remain throughout the building, alongside on-site parking.

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    Mount Pleasant Retail/Office/Medical Space
    Mount Pleasant Retail/Office/Medical Space

    1123 Queensborough Boulevard, Mount Pleasant, SC 29464

    $30 SF/Yr
    3,949 sqft

    3,949 SF space ideal for retail, office, or medical.

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    Dental-To-Medical Office Suite
    Dental-To-Medical Office Suite

    1065-C Johnnie Dodds Blvd, Mount Pleasant, SC 29464

    Contact for pricing
    1,500 sqft

    Turn-key office currently set up for dental use, positioned across from a major hospital with convenient highway access.

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    Updated Freestanding Office Building
    Updated Freestanding Office Building

    2132 Dorchester Road, North Charleston, SC 29405

    Contact for pricing

    Updated commercial space includes private offices, a kitchen, restroom, and surface parking.

    View details

    Similar Spaces for Sale in Daniel Island, SC

    Consider Similar Space for Sale. We found 1 Spaces matching your search parameters.

    Downtown Medical Office Condo
    Downtown Medical Office Condo

    198 Rutledge Avenue, Charleston, SC 29403

    $1,740,000

    First-floor office condo with dedicated parking near Charleston’s hospital district.

    View details

    Daniel Island, SC Medical Office Space Lease Rates & Market Statistics

    Browse 7 Medical Office Space listings for lease in Daniel Island, SC on Realmo, a commercial real estate marketplace serving the Daniel Island area. The current inventory totals 32,176 square feet of properties.

    Medical Office Space lease rates in Daniel Island range from $8.28 SF/Yr at the entry level to $35 SF/Yr at the top of the market, averaging $21.64 SF/Yr. That's a 4x spread between entry-level and premium space, making side-by-side comparison of asking rents and lease terms essential. The local average of $21.64 SF/Yr is in line with the South Carolina state average.

    Medical Office Space listings make up 6% of the 110 Office Spaces currently for lease in Daniel Island, with asking rates averaging $21.64 SF/Yr — 29% below the citywide Office Spaces average of $30.32 SF/Yr. Tenants comparing options may also consider Office Units (84 listings) and Office buildings (23 listings) elsewhere in the Daniel Island market.

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    Most Searched ZIP Codes in Daniel Island, SC

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    • 29407
    • 29412
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