New York, NY Medical Office Space for Rent & Lease

Updated: Jun 28

Turn-Key Storefront Medical Office

60-06 Fresh Pond Road, Maspeth N Y, Ny, NY 11378

$4,500/Mo

2,470 sqft 0.04 AC lot

1,235 SF turn‑key storefront on Fresh Pond Road in a high‑traffic area
Brick construction with laminate flooring and high ceilings
Waiting area with a large open floor plan plus 3 separate rooms
Newly renovated bathroom (Bathroom 1)
Full‑length basement providing additional storage space

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Updated: Aug 3

First-Floor Medical Office Space

23 W 73rd Street #101 Room 4, New York (, Manhattan, NY 10023

$3,600/Mo

Approximately 553 SF total, including a 236 SF private office and 317 SF common area
First‑floor location positioned off the lobby
Shared waiting area and two shared bathrooms
Configured as a private psychiatrist’s office
Immediate possession with negotiable lease term

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Medical Office Space with Two Bathrooms

120-08 131 Street, New York, NY 11420

$4,999/Mo

Flexible multi-room layout with open, treatment, private office, and support areas for professional service operations.

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Second-Floor Office Unit

3610 Main Street, New York, NY 11354

$8,800/Mo

2,400 sqft

Second-floor commercial space near the 7 Train, Main Street Station, bus routes, shopping, dining, and neighborhood services.

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Medical Office Build-to-Spec Space

47-01 Queens Boulevard, New York, NY 11104

$45 SF/Yr

5,181 sqft

Medical office space with ADA elevators and ADA-compliant bathrooms, configured for build-out to practice specifications.

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Medical Office Suite with 24-Hour Doorman

115 E 61st Street Unit: 4C, New York (, Manhattan, NY 10065

$9,500/Mo

2,000 sqft

Medical and professional services suite in a Lenox Hill medical hub with 24-hour doorman service.

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Turn-Key Medical Office in Gramercy

7 Lexington Avenue, New York, NY 10010

$3,500/Mo

700 sqft

Medical office space for lease in Gramercy Park neighborhood.

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Renovated Second-Floor Office

134 W 32nd St, New York, NY 10016

$5,500/Mo

1,700 sqft

Newly renovated second-floor office space with two half bathrooms and two included parking spaces.

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Boutique Office/Medical Building Near Park

250 West 57th Street, New York, NY 10107

$65 SF/Yr

5,300 sqft

16-story office/medical building near Central Park and Carnegie Hall.

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Midtown Building with Private Lobby

133 West 52nd Street, New York, NY 10019

$65 SF/Yr

12,789 sqft

55,000 sq ft vacant building ideal for healthcare, education.

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Lenox Hill Medical Office Space

20 East 68th Street, New York, NY 10065

$6,050/Mo

854 sqft

Professional/medical office for lease in Lenox Hill, Manhattan.

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First-Floor Medical Office Suite

23 West 73rd Street #101 Room 4, New York, NY 10023

$3,600/Mo

Private psychiatrist office with shared waiting area and two shared bathrooms.

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Medical Office Building with Elevator

168 E 80th St, New York, NY 10075

Contact for pricing

8,637 sqft

New construction provides six full-floor commercial units along Manhattan’s Upper East Side medical corridor.

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Corner Medical Office Space

324 West 125th Street, New York, NY 10027

Contact for pricing

6,780 sqft

Fully built medical premises with immediate availability, natural light, and direct access to the 125 St station.

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Office Suite with Two Rooms

7 Chatham Sq 202, New York, NY 10038

$2,300/Mo

Neat two-room office suite inside an elevator building with 24-hour doorman service.

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Medical Office Suite Above CVS

324 W 125th st, New York, NY 10027

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6,780 sqft

Second-floor corner suite with elevator access above CVS and high-capacity electrical service for power-intensive medical uses.

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Flexible Office Units

197 3rd Ave, New York, NY 10003

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3,108 sqft

Office space supports medical, community, daycare, and education uses with flexible division options and an onsite parking garage.

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Medical Office Suite at Transit Hub

185 Greenwich Street, New York, NY 10007

Contact for pricing

2,606 sqft

West Concourse Level 2 suite with 41+ feet of frontage along a high-traffic pedestrian corridor in a major downtown retail complex.

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Medical Office Space with Exam Rooms

250 W 57th St, New York, NY 10019

Contact for pricing

3,022 sqft

Medical office faces 57th Street and includes four exam rooms, an x-ray room, reception, and two private restrooms.

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Transit-Connected Medical Office Space

175 Greenwich St, New York, NY 10006

Contact for pricing

1,684 sqft

West Concourse suite positioned along a pedestrian corridor connecting office, rail, subway, and ferry destinations.

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Flexible Office Space

C14-3370 Prince Street, New York, NY 11354

$2,500/Mo

Flexible office space available for lease in Flushing’s commercial district, suitable for professional, medical, or service use.

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Flexible Office Suite

C13-3370 Prince Street, New York, NY 11354

$2,500/Mo

Flexible office space available for lease in Flushing’s commercial district.

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Class-A Medical Office Building

110 E 60th St, New York, NY 10022

Contact for pricing

58,511 sqft

Prebuilt suites and medical infrastructure support Article 28 users.

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Premium Medical Suite in Lenox

115 E 61st St 4D, New York, NY 10065

$3,800/Mo

Prime Lenox Hill medical suite for licensed professionals.

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New York, NY Medical Office Space Lease Rates & Market Statistics

Explore 111 Medical Office Space listings for lease in New York, NY on Realmo, a commercial real estate exchange covering the New York area. The current inventory totals 520,386 square feet of properties — an average of ~4,700 SF per listing.

Asking lease rates for Medical Office Space in New York start at $21.86 SF/Yr, average $51.85 SF/Yr, and reach $85.01 SF/Yr at the top of the market. That's a 4x spread between entry-level and premium space, making side-by-side comparison of asking rents and lease terms essential. The local average of $51.85 SF/Yr is 65% above the New York state average of $31.33 SF/Yr.

Medical Office Space listings make up 7% of the 1,521 Office Spaces currently for lease in New York, with asking rates in line with the citywide Office Spaces average. Also worth a look for tenants weighing alternatives: Office Units (865 listings) and Office buildings (558 listings) elsewhere in the New York market.