Lafayette County, MO Commercial Real Estate for Lease

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Two-Story Medical Office Suites
Updated: Dec 18, 2025
Two-Story Medical Office Suites

316 W US Hwy 40, Odessa, MO 64076

Contact for pricing
1,750 sqft 1.75 AC lot
11,000 SF, two‑story building on a 1.75‑acre lot
Lower‑level office spaces for rent: 1,750 SF and 2,200 SF
Street level is 100% occupied by a Medical Group and a Nail Salon
Ample on‑site parking plus room to add an additional building
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Warehouse with Drive-In Loading
Updated: Aug 14, 2025
Warehouse with Drive-In Loading

702 E 1st St, Concordia, MO 64020

Contact for pricing
16,151 sqft 4.03 AC lot
16,151± SF warehouse plus 4,500± SF office on B‑2: Highway Business District land
Up to 14’-30’ clear height with 7 drive‑in loading doors
7.50 PSF IG lease rate and $1,600,000 sale price
4.03 AC land with two outbuildings totaling 2,500 SF, each with drive‑in doors
Highway traffic: approximately 56,000 vehicles per day pass by along I‑70
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The Shops at Odessa
The Shops at Odessa

1212 U.S. Hwy 40, Odessa, MO 64076

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198,500 sqft

Strategically located retail destination with high traffic and expansion potential.

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Based on your search, we've compiled 71 Potential Opportunities for your consideration. Besides 3 Active listings in Lafayette County, MO, we suggest exploring alternatives. Similar 68 Properties for Sales.

Similar Spaces for Sale in Lafayette County, MO

Consider Similar Space for Sale. We found 68 Spaces matching your search parameters.

Automotive Shop with High-Clear Bay
Automotive Shop with High-Clear Bay

120 W Us Highway 40, Odessa, MO 64076

$400,000
3,300 sqft

Configured for automotive operations with office, restrooms, utility hookups, and security equipment.

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Renovated Medical Office Building
Renovated Medical Office Building

1717 N Main Street, Higginsville, MO 64037

$399,000
7,100 sqft

Fully renovated medical office building with multiple exam rooms, reception, staff workspaces, and four bathrooms.

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Versatile Commercial Property For Sale
Versatile Commercial Property For Sale

309 Park Ln, Odessa, MO

$389,000
8,000 sqft

8,000 SF commercial property with highway visibility in growing area.

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Commercial Land with Workshop
Commercial Land with Workshop

6399 Oakview Lane, Higginsville, MO 64037

$799,000
41.00 AC lot

Ag/Res-zoned land with public water, a climate-controlled workshop, and access from Highway 13 and the South Outer Road.

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Updated Office Building
Updated Office Building

213 S 2nd Street, Odessa, MO 64076

$200,000
0.07 AC lot

Multi-room commercial office property with refreshed roof and air-conditioning systems.

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Commercial Land with Highway Frontage
Commercial Land with Highway Frontage

40 Highway 40, Higginsville, MO 64037

$250,000
475,239 sqft

Unimproved land currently used for agricultural production along a publicly maintained asphalt route near Interstate 70.

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Updated Conventional Restaurant
Updated Conventional Restaurant

100 Fairground Avenue, Higginsville, MO 64037

$120,000
0.18 AC lot

Restaurant facility with installed food-service equipment, furnishings, customer parking, and a detached storage shed.

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Agricultural Land with Ponds
Agricultural Land with Ponds

3431 Old Stage Road, Mayview, MO 64071

$649,999
3,136,320 sqft

Open acreage includes tillable ground, pasture fencing, seasonal water, and utility availability at the road.

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Drug Store Building with Parking
Drug Store Building with Parking

101 S 2nd Street, Odessa, MO 64076

$1,200,000
0.15 AC lot

Retail building occupied by a national tenant in Odessa’s downtown business district with on-site parking.

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Higginsville Office Building For Sale
Higginsville Office Building For Sale

3401 Pine Street & 810 W. 35th Street, Higginsville, MO 64037

Contact for pricing
11,200 sqft

Office building with 11,200 square feet of space.

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Drug Store Building with Parking
Drug Store Building with Parking

1030 Main Street, Lexington, MO 64067

$1,200,000
0.21 AC lot

Freestanding commercial building with a parking lot, water availability, and an established long-term lease structure.

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C2 Commercial Land Near Highway 24
C2 Commercial Land Near Highway 24

736 S Business Hwy 13, Lexington, MO 64067

$100,000
4.51 AC lot

C2-zoned commercial land positioned between Business Highway 13 and Highway 24.

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Steel-Frame Flex Space
Steel-Frame Flex Space

1661 Highway 13 Boulevard, Higginsville, MO 64037

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12,100 sqft 2.40 AC lot

Steel-frame commercial space offers an open layout, loading dock, storage, and parking for adaptable business operations.

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Auto Repair Building with Drive-Through
Auto Repair Building with Drive-Through

315 W Mason St, Odessa, MO 64076

Contact for pricing
11,400 sqft 1.00 AC lot

Steel clear-span construction includes elevated office and locker space.

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Flex Space with Loft
Flex Space with Loft

225 S 2nd Street, Odessa, MO 64076

$450,000
0.29 AC lot

Two-level commercial building with showroom, shop, office areas, delivery access, and C1 zoning.

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Gas Station with Mechanic Bays
Gas Station with Mechanic Bays

101 NW Railroad St, Odessa, MO 64076

$275,000

Corner-site commercial property with service-bay and storage improvements.

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Historic Storefront Building with Freight Elevator
Historic Storefront Building with Freight Elevator

1802 Franklin Avenue, Lexington, MO 64067

$70,000
0.24 AC lot

Historic storefront building with freight elevator, 12-foot ceilings, brick courtyard, and C zoning.

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Two-Level Flex Space with Loading Docks
Two-Level Flex Space with Loading Docks

116 W 19TH Street, Higginsville, MO 64037

$350,000
16,276 sqft

Two-level commercial building combines front offices with rear warehouse space and extensive on-site parking.

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Updated Creative Space
Updated Creative Space

206 S 12th Street, Lexington, MO 64067

$90,000
0.05 AC lot

Flexible commercial interior with reception, studio, private offices, and courtyard access in Lexington’s downtown business district.

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Downtown Retail Suite with Open Floor
Downtown Retail Suite with Open Floor

531 S Main, Concordia, MO 64020

Contact for pricing
2,190 sqft

Retail suite offers a 30' x 60' open area plus a 15' x 26' back room work area.

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Two-Building Self Storage Property
Two-Building Self Storage Property

116 N 9th St, Lexington, MO 64067

$140,000

Includes an electrically serviced storage building and a second structure configured for mini-storage rentals.

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Lafayette County, MO Commercial real estate Market Trends and Statistics

Explore Commercial real estate leasing options in Lafayette County, MO with 3 listings featured on our commercial real estate exchange. The current inventory includes 216,401 square feet of properties.
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