Lafayette County, MO Commercial Real Estate for Lease

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Two-Story Medical Office Suites
Updated: Dec 18, 2025
Two-Story Medical Office Suites

316 W US Hwy 40, Odessa, MO 64076

Contact for pricing
1,750 sqft 1.75 AC lot
11,000 SF, two‑story building on a 1.75‑acre lot
Lower‑level office spaces for rent: 1,750 SF and 2,200 SF
Street level is 100% occupied by a Medical Group and a Nail Salon
Ample on‑site parking plus room to add an additional building
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Warehouse with Drive-In Loading
Updated: Aug 14, 2025
Warehouse with Drive-In Loading

702 E 1st St, Concordia, MO 64020

Contact for pricing
16,151 sqft 4.03 AC lot
16,151± SF warehouse plus 4,500± SF office on B‑2: Highway Business District land
Up to 14’-30’ clear height with 7 drive‑in loading doors
7.50 PSF IG lease rate and $1,600,000 sale price
4.03 AC land with two outbuildings totaling 2,500 SF, each with drive‑in doors
Highway traffic: approximately 56,000 vehicles per day pass by along I‑70
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Based on your search, we've compiled 57 Potential Opportunities for your consideration. Besides 2 Active listings in Lafayette County, MO, we suggest exploring alternatives. Similar 55 Properties for Sales.

Similar Spaces for Sale in Lafayette County, MO

Consider Similar Space for Sale. We found 55 Spaces matching your search parameters.

Automotive Shop with High-Clear Bay
Automotive Shop with High-Clear Bay

120 W Us Highway 40, Odessa, MO 64076

$380,000
3,300 sqft

Configured for automotive operations with office, restrooms, utility hookups, and security equipment.

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Renovated Medical Office Building
Renovated Medical Office Building

1717 N Main Street, Higginsville, MO 64037

$399,000
7,100 sqft

Fully renovated medical office building with multiple exam rooms, reception, staff workspaces, and four bathrooms.

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Log Cabin on Highway 40
Log Cabin on Highway 40

121 W Us Highway 40 N/A, Odessa, MO 64076

$350,000
3,980 sqft 0.41 AC lot

Versatile log cabin suitable for retail, office, or hospitality.

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Versatile Commercial Property For Sale
Versatile Commercial Property For Sale

309 E Park Ln, Odessa, MO 64076

$389,000
8,000 sqft

8,000 SF commercial property with highway visibility in growing area.

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Historic Corner Storefront
Historic Corner Storefront

901 Franklin Avenue, Lexington, MO 64067

$165,000
0.08 AC lot

Single-story commercial space with updated systems, display windows, and a fenced brick courtyard.

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Two-Story Mixed-Use Building
Two-Story Mixed-Use Building

1007 Franklin Avenue, Lexington, MO 64067

$159,000
0.06 AC lot

The ground floor has a commercial kitchen setup, while a separate apartment occupies the upper level.

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Multi-Room Office Units
Multi-Room Office Units

213 S 2nd Street, Odessa, MO 64076

$180,000
0.07 AC lot

Flexible room configuration supports private offices, meetings, and collaborative work.

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Updated Conventional Restaurant
Updated Conventional Restaurant

100 Fairground Avenue, Higginsville, MO 64037

$120,000
0.18 AC lot

Restaurant facility with installed food-service equipment, furnishings, customer parking, and a detached storage shed.

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Mixed-Use Building with Flexible Layout
Mixed-Use Building with Flexible Layout

108 E Kelling Avenue, Waverly, MO 64096

$74,500
0.07 AC lot

As-is property with central air, forced-air heating, and a layout adaptable to retail, office, or service use.

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Rehabilitated Storefront with Kitchen
Rehabilitated Storefront with Kitchen

209 S 2nd St, Odessa, MO 64076

$245,000

Historic-district storefront with commercial kitchen infrastructure, updated systems, and employee parking behind the building.

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Mixed-Use Building with Restroom
Mixed-Use Building with Restroom

108 E Kelling Avenue, Waverly, MO 64096

$74,500
0.07 AC lot

Flexible commercial space with a private restroom, on-street parking, and water available.

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Drug Store Building with Parking
Drug Store Building with Parking

101 S 2nd Street, Odessa, MO 64076

$1,200,000
0.15 AC lot

Retail building occupied by a national tenant in Odessa’s downtown business district with on-site parking.

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Drug Store Building with Parking
Drug Store Building with Parking

1030 Main Street, Lexington, MO 64067

$1,200,000
0.21 AC lot

Freestanding commercial building with a parking lot, water availability, and an established long-term lease structure.

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Commercial Land with Highway Access
Commercial Land with Highway Access

736 S Business Hwy 13, Lexington, MO 64067

$100,000
4.51 AC lot

C2-zoned commercial land positioned off Business Highway 13 near Highway 24.

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Brick Storefront with Storage
Brick Storefront with Storage

211 W Mason St, Odessa, MO 64076

$150,000

Downtown commercial building with finished space, a bath, private work area, and unfinished rear storage.

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Gas Station with Mechanic Bays
Gas Station with Mechanic Bays

101 NW Railroad St, Odessa, MO 64076

$275,000

Corner-site commercial property with service-bay and storage improvements.

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Storefront Building with Storage
Storefront Building with Storage

1007 Franklin Avenue, Lexington, MO 64067

$159,000

Commercial zoning and an in-law floorplan add to the building’s practical configuration.

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Retail Storefront on Main Street
Retail Storefront on Main Street

723 S Main St, Concordia, MO 64020

$169,000

For sale storefront retail property located on the east side of Main Street.

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Updated Creative Space
Updated Creative Space

206 S 12th Street, Lexington, MO 64067

$90,000
0.05 AC lot

Flexible commercial interior with reception, studio, private offices, and courtyard access in Lexington’s downtown business district.

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Industrial Land Near I-70
Industrial Land Near I-70

Lot 12 N Oak Street, Bates City, MO 64011

$163,350
1.39 AC lot

1.39 acre industrial lot with I-70 visibility.

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Steel-Related Flex Warehouse Building
Steel-Related Flex Warehouse Building

110 W Mason St, Odessa, MO 64076

$275,000

Flex warehouse building with signage reading J D Steel and access adjoining a city alley.

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Two-Building Self Storage Property
Two-Building Self Storage Property

116 N 9th St, Lexington, MO 64067

$140,000

Includes an electrically serviced storage building and a second structure configured for mini-storage rentals.

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Lafayette County, MO Commercial real estate Market Trends and Statistics

Explore Commercial real estate leasing options in Lafayette County, MO with 2 listings featured on our commercial real estate exchange. The current inventory includes 17,901 square feet of properties.
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