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    Middlesex County, MA Medical Office Space for Lease

    54 results
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    Medical Office Space Near Hospital
    $2,200 /Mo
    2,518 SF

    Medical Office Space Near Hospital

    140 Lincoln St., Framingham, MA 1702

    Move-in ready medical office space near Metrowest Medical Center.

    • Prime location next to Metrowest Medical Center, ideal for medical practices.
    • Move‑in ready medical office space with existing reception, waiting area, 4 offices, kitchenette, and bathroom.
    • Established medical building within a healthcare ecosystem.
    • Convenient location near Route 135.
    • ± 1,000 SF of first‑floor space in a 2,518 SF building.
    Updated: Nov 21, 2025
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    Medical & Professional Suites Available
    Contact for pricing
    1,352 SF

    Medical & Professional Suites Available

    411 Massachusetts Ave, Acton, MA 1720

    Medical and professional suites for lease in Acton, Massachusetts.

    • Prime location directly off Route 2 at the intersection of Route 27 and Route 111, providing convenient regional access.
    • Ample on‑site parking for employees, patients, and visitors.
    • Amenity‑rich surroundings with an adjacent shopping plaza anchored by Roche Bros., TJ Maxx, HomeGoods, and Not Your Average Joe’s.
    • Well‑maintained building occupied by a network of medical and professional users.
    • Suites available on multiple floors (2nd and 3rd) with varying square footage options.
    Updated: Mar 6
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    Woburn Flex Space For Lease
    Contact for pricing
    11,573 SF

    Woburn Flex Space For Lease

    11,573 SF flex space with drive-in door near I-93.

    4 Presidential Way, Woburn, MA 1801
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    Brookline Village Office/Commercial Suite
    $35 SF/Yr
    8,047 SF

    Brookline Village Office/Commercial Suite

    8047 SF office suite in Brookline Village for lease.

    60-62 Harvard #2A, Brookline, MA 2445
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    Natick Office/Medical Space Available
    Contact for pricing
    2,275 SF

    Natick Office/Medical Space Available

    Office/medical space for lease in Natick, Massachusetts.

    67 Union Street, Natick, MA 1760
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    Medical Office Space in Billerica
    Contact for pricing
    7,750 SF

    Medical Office Space in Billerica

    Highly visible medical/office space with existing buildout and easy highway access.

    790 Boston Road, Billerica, MA 1821
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    Prime Somerville Retail Space Available
    $53 SF/Yr

    Prime Somerville Retail Space Available

    High-traffic retail space near Whole Foods and MBTA Red Line.

    70 Beacon #2, Somerville, MA 2143
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    Lowell Office Space For Lease
    $20 SF/Yr
    4,800 SF

    Lowell Office Space For Lease

    4,700 SF unfinished space with custom build-out opportunity.

    595 Pawtucket Blvd, Lowell, MA
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    Retail, Medical, Office Space Available
    Contact for pricing
    8,920 SF

    Retail, Medical, Office Space Available

    First floor retail, medical, and office space for lease.

    69 East Central Street, Natick, MA 1760
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    Flex Office Space in Winchester
    Contact for pricing
    46,313 SF

    Flex Office Space in Winchester

    5,200 SF flex office space for lease in Winchester.

    Winchester, MA 01890
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    Everett Broadway Versatile Office Space
    $1,600 /Mo
    550 SF

    Everett Broadway Versatile Office Space

    Street-level office suite suitable for various professional uses.

    563 Broadway #B2, Everett, MA 2149
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    Medical Office Space Available
    Contact for pricing
    1,375 SF

    Medical Office Space Available

    Class A medical office suites for lease in Marlborough, MA.

    340 Maple St, Marlborough, MA
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    Medical Office Suite For Rent
    $1,100 /Mo

    Medical Office Suite For Rent

    Medical office suite in Mass Eye and Ear and Tufts medical building.

    578 Main Street #104, Malden, MA 2148
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    Medical Office Space Available
    $2,750 /Mo

    Medical Office Space Available

    Professional building with flexible layout, ideal for medical or office.

    521 Mount Auburn #209, Watertown, MA 2474
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    Medical Office Space Available
    Contact for pricing
    8,857 SF

    Medical Office Space Available

    Medical office space for lease in Marlborough, Massachusetts.

    640 Bolton Street, Marlborough, MA 1752
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    Natick Medical Office Space
    Contact for pricing

    Natick Medical Office Space

    Medical office space available in downtown Natick.

    12 West Central Street, Natick, MA 1760
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    Move-in Ready Sudbury Commercial Condo
    $2,200 /Mo

    Move-in Ready Sudbury Commercial Condo

    First-floor commercial condo in Sudbury, suitable for various professional services.

    323 Boston Post Rd #2A, Sudbury, MA 1776
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    Medical Office Space Available
    Contact for pricing
    10,800 SF

    Medical Office Space Available

    Highly visible medical/office space with existing exam rooms.

    790 Boston Rd, Billerica, MA 1821
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    Brookline Office Space on Beacon
    $7,000 /Mo
    165,000 SF

    Brookline Office Space on Beacon

    Second-floor office suite in Brookline's Washington Square district.

    1560 Beacon St #2nd Floor, Brookline, MA 2446
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    Washington Square Office Suite
    $7,500 /Mo
    150,383 SF

    Washington Square Office Suite

    2,200 SF office suite in Brookline's Washington Square.

    1560 Beacon St #3rd Floor, Brookline, MA 2446
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    Malden Center Commercial Suite
    $3,500 /Mo
    1,510 SF

    Malden Center Commercial Suite

    1,510 sq ft commercial suite in Malden Center.

    599 Main St, Malden, MA 2148
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    Bright Corner Office Suite
    Contact for pricing
    1,496 SF

    Bright Corner Office Suite

    Well-appointed office suite with abundant natural light, near Boston.

    2-100 Tower Office Park, Woburn, MA
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    Retail Space in Ashland, MA
    Contact for pricing
    200,000 SF

    Retail Space in Ashland, MA

    Ground-level retail opportunity in a vibrant, convenient Ashland location.

    100 Chestnut Street, Ashland, MA 1721
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    Natick Medical Office Space Available
    Contact for pricing
    4,449 SF

    Natick Medical Office Space Available

    First floor medical office space for lease in Natick.

    12 West Central Street, Natick, MA 1760
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    Middlesex County, MA Medical Office Space Leasing Opportunities Market Analysis

    Explore Medical Office Space leasing options in Middlesex County, MA with 54 listings featured on our commercial real estate exchange. The current inventory includes 148,496,040 square feet of properties with an estimated lease value of $172 SF/Yr.

    Estimated lease rates for Medical Office Space in Middlesex County, MA begin at $23 SF/Yr, with an average of $34 SF/Yr and extend to $45 SF/Yr.
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    Browse Medical Office Space for Lease Near Middlesex, MA

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