Saint Matthews, KY Medical Office Space for Lease

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Lyndon, KY Hurstbourne, KY Hurstbourne Acres, KY Jeffersonville, IN Jeffersontown, KY Prospect, KY Jeff, IN Middletown, KY

18 properties

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Updated: May 14

Second-Floor Office Condo Suite

800 Stone Creek Pkwy, Louisville, KY 40223

$1,100/Mo

1,100 sqft

1,100 SF second‑floor office condo suite with a large waiting/reception area
Includes four oversized private offices with abundant natural light
Two private offices have sink hookups for added flexibility
Kitchenette and private restroom included in the suite
Located in the Stone Creek Parkway office corridor in east Louisville near Hurstbourne Pkwy and I‑64

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Updated: Jun 25

Medical Office Building with Exam Rooms

6500 Preston Hwy, Unit: 1, Louisville, KY 40219

$19,500/Mo

12,009 sqft

12,009 SF medical office building at 6500 Preston Hwy near Fern Valley Rd
Multiple patient/exam rooms designed for efficient workflow and patient accessibility
Ample on‑site parking for patients and staff
Elevator access to basement level, with a large basement for storage or additional operational use
Functional layout supporting medical, dental, and specialty healthcare uses

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Office Space Near Holiday Manor

4912 U.S. 42, Louisville, KY 40222

$25 SF/Yr

8,385 sqft

Medical and traditional office space with excellent visibility and access.

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Medical Office Suite in Office Building

4036 Dutchmans Lane, Louisville, KY 40207

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1,800 sqft

1,800 SF office space behind Pro Scan Imaging, formerly a home health agency, across from Norton Women’s and Children’s.

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Medical Office Suites with Surface Parking

4912 US Hwy 42, Louisville, KY 40222

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1,449 sqft

Medical and traditional office suites offer excellent visibility and access with ample surface parking.

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Medical Office Building

6500 Preston Hwy, Louisville, KY 40219

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12,009 sqft

Well-equipped medical office building with numerous exam rooms, offering visibility along a busy Preston Highway corridor.

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Medical Office Space with Signage

205 Moser Rd, Louisville, KY 40243

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2,200 sqft

C-1 Commercial zoning, monument signage, and nearby retail and service anchors support a visible Middletown submarket location.

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Medical Office Suite with Monument Signage

205 Moser Road, Louisville, KY 40223

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2,200 sqft

For-lease medical office space featuring monument signage and C-1 commercial zoning.

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Free-Standing Medical Office Building

3130 Portland Ave, Louisville, KY 40212

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9,258 sqft

Free-standing building totaling 9,258 SF with prominent Portland Avenue frontage and signage opportunities.

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Turnkey Two-Story Medical Office Building

1915 Bishop Lane, Louisville, KY 40218

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Turnkey two-floor medical office building with exam rooms and existing patient-flow infrastructure.

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Walmart-Anchored Shopping Center

161 Outer Loop, Louisville, KY 40214

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Retail and medical office vacancies include a 2,000 SF inline suite with shared customer and employee parking.

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Multi-Tenant Retail Center Lease Space

5240 Dixie Hwy, Louisville, KY 40216

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44,283 sqft 3.44 AC lot

5,283 SF retail suite available within Dixie Center, an established multi-tenant center with prominent Dixie Highway frontage and onsite parking.

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Downtown Louisville Medical Office Space

645 Roy Wilkins Ave, Louisville, KY 40203

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Medical office space in Downtown Louisville's Central Business District.

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Eight-Story Medical Office Space

100 E Liberty St, Louisville, KY 40202

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68,344 sqft

Outpatient medical space with surface parking, nearby retail and restaurants, and convenient access to I-65.

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Renovated Office Units

1169 Eastern Pkwy, Louisville, KY 40204

$18 SF/Yr

155,000 sqft

Flexible suites support medically oriented practices and business offices within a recently upgraded, ADA-compatible building.

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Medical Clinic & Office Building

9616 Dixie Hwy, Louisville, KY 40272

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10,500 sqft 2.76 AC lot

Medical clinic and office building in high-traffic area.

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Medical Office Suites on Healthcare Campus

9702 Stonestreet Rd, Louisville, KY 40272

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52,302 sqft

Medical office suites on an established healthcare campus with patient parking, imaging, diagnostic services, and emergency care nearby.

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Eight-Story Medical Office Building

3999 Dutchmans Lane, Saint Matthews, KY 40207

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111,246 sqft

Physician suites can be custom configured within a renovated building on a hospital campus with surface parking.

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Based on your search, we've compiled 40 Potential Opportunities for your consideration. Besides 18 Active listings in Saint Matthews, KY, we suggest exploring alternatives. Similar 22 Properties for Sales.

Similar Spaces for Sale in Saint Matthews, KY

Consider Similar Space for Sale. We found 22 Spaces matching your search parameters.

Two-Story Office Condominium Building

3401 Stony Spring Circle, Louisville, KY 40220

$800,000

5,600 sqft 52.90 AC lot

All-brick, two-story office condominium features four separate units with ample parking in the Louisville area.

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Freestanding Medical Office

4516 Outer Loop, Louisville, KY 40219

$377,656

2,417 sqft 0.28 AC lot

Existing clinical configuration includes treatment, laboratory, consultation, and patient-support areas.

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Two-Story Dentist Office Building

4213 N. Church Way, Louisville, KY 40207

$499,000

2,984 sqft

Two-story dentist office with an unfinished basement and ample parking, offered for sale in OR-3 zoning.

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Turnkey Medical Office Building

10300 Dixie Hwy, Louisville, KY 40272

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5,250 sqft

Turnkey medical office building with seven exam rooms, dedicated X-ray room, and 22 on-site parking spaces.

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Medical Office Space with Covered Patio

2009 Frankfort Ave, Louisville, KY 40206

$399,000

800 sqft

Updated commercial building with a flexible layout, outdoor amenity, and established mixed-use surroundings near downtown Louisville.

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Office Building with Monument Sign

827 East Broadway, Louisville, KY 40204

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5,208 sqft

C-2 zoning, dedicated off-street parking, and a monument sign serve this Louisville office property.

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Saint Matthews, KY Medical Office Space Lease Rates & Market Statistics

Browse 18 Medical Office Space listings for lease in Saint Matthews, KY on Realmo, a commercial real estate marketplace serving the Saint Matthews area. The current inventory totals 492,085 square feet of properties — an average of ~27,350 SF per listing.

Asking lease rates for Medical Office Space in Saint Matthews start at $12 SF/Yr, average $18.62 SF/Yr, and reach $25 SF/Yr at the top of the market. Pricing across the market is relatively uniform, which simplifies like-for-like comparison between listings. At $18.62 SF/Yr, the local average runs 18% above Kentucky's state average of $15.74 SF/Yr.

Saint Matthews accounts for 100% of the 18 medical office space listings currently available across Jefferson County, where a nearby market includes Louisville. Medical Office Space listings make up 9% of the 190 Office Spaces currently for lease in Saint Matthews, with asking rates averaging $18.62 SF/Yr — 11% above the citywide Office Spaces average of $16.79 SF/Yr. Tenants comparing options may also consider Office Units (119 listings) and Office buildings (60 listings) elsewhere in the Saint Matthews market.

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