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    Arapahoe County, CO Medical Office Space for Lease

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    37 properties
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    Renovated Medical Office Suite
    Updated: May 1
    Renovated Medical Office Suite

    8089 S Lincoln St, Littleton, CO 80122

    $2,261/Mo
    Suite 201 contains 1,085 square feet of office space
    Renovated medical and professional office building
    Elevator access and 24‑hour building entry
    Monument signage opportunities available
    Ample on‑site parking for employees and clients
    View details
    Turn-Key Retail/Office Building
    Updated: Jul 13
    Turn-Key Retail/Office Building

    1238-1248 S Broadway, Denver, CO 80210

    $22 SF/Yr
    4,343 sqft
    Bank‑built retail/office property built in 1975 with 4,343 SF total space
    Previously used as a major bank branch and most recently occupied as a physical therapy center
    Updated, modern utilities included
    Approximately one‑third of the building remains unfinished, previously used as back‑of‑house storage for added customization flexibility
    Space offered for immediate lease
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    Ground-Floor Medical Office Suite
    Ground-Floor Medical Office Suite

    384 Inverness Pkwy, Englewood, CO 80112

    $22 SF/Yr
    2,992 sqft

    Remodeled ground-floor suite with free surface parking and built-in nursing station for office or medical use.

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    Medical Office Space with Plumbed Treatment Rooms
    Medical Office Space with Plumbed Treatment Rooms

    5 North Cook Street, Denver, CO 80206

    $43.50 SF/Yr
    2,001 sqft

    Prominent hard-corner medical office with plumbed treatment rooms, patient areas, and covered off-street parking.

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    Commercial Spaces For Lease
    Commercial Spaces For Lease

    340 W Hampden Ave, Englewood, CO 80110

    $25 SF/Yr
    1,400 sqft 0.46 AC lot

    Versatile spaces suitable for retail, office, medical, or flex.

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    Dental Medical Office Suite
    Dental Medical Office Suite

    700 E Speer Blvd, Denver, CO 80203

    $9,400/Mo

    Fresh interior finishes, available signage, and on-site parking support a ready-to-occupy dental practice.

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    Medical Office Condo Suite
    Medical Office Condo Suite

    8751 E Hampden Avenue Unit: A6, Denver, CO 80231

    $3,900/Mo

    Vacant office condo suite previously used as a massage spa within a three-building commercial complex.

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    Englewood Commercial Spaces For Lease
    Englewood Commercial Spaces For Lease

    340 W Hampden Avenue, Englewood, CO 80110

    $25 SF/Yr
    8,684 sqft 0.46 AC lot

    Versatile spaces suitable for retail, office, medical, or flex use.

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    Retail Space Formerly Used as Urgent Care
    Retail Space Formerly Used as Urgent Care

    3890 Quebec St, Denver, CO 80207

    Contact for pricing
    4,428 sqft

    Lease opportunity with access to I-70 and nearby national retail anchors.

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    Turn-Key Medical Spa with Treatment Rooms
    Turn-Key Medical Spa with Treatment Rooms

    7939 East Arapahoe Road, Greenwood Village, CO 80112

    Contact for pricing
    1,606 sqft

    Turn-key medical spa with four dedicated treatment rooms and secure key-code after-hours access.

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    Flexible Office Units with Natural Light
    Flexible Office Units with Natural Light

    1115 W 11th, Denver, CO 80204

    $4,000/Mo

    Professional workspace offers private-office and collaborative configurations near downtown amenities.

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    Light-Filled Office Units
    Light-Filled Office Units

    1115 W 11th Avenue, Denver, CO 80204

    $4,000/Mo

    Flexible layouts support private offices and collaborative work areas for professional, medical, and creative users.

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    Medical Outpatient Building with Rooftop
    Medical Outpatient Building with Rooftop

    1818 North Ogden Street, Denver, CO 80218

    Contact for pricing
    18,366 sqft

    New outpatient medical building featuring a 5th-floor tenant rooftop common area with downtown and mountain views.

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    Updated Office Medical Building
    Updated Office Medical Building

    6979 S Holly Circle, Centennial, CO 80112

    $24 SF/Yr
    29,788 sqft

    29,755 SF office medical building with ample parking.

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    Medical Office Suite with Patio
    Medical Office Suite with Patio

    6650 S Vine St, Centennial, CO 80121

    Contact for pricing
    2,884 sqft

    Move-in-ready suite includes a kitchen and multiple offices, with in-place plumbing and compressed air for medical use.

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    Medical Office Building with Surgery Center
    Medical Office Building with Surgery Center

    8381 Southpark Ln, Littleton, CO 80120

    Contact for pricing
    17,792 sqft

    A zoned BC/PL-O medical office building with multiple suites anchored by a licensed surgery center.

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    Medical Flex Facility with Loading Dock
    Medical Flex Facility with Loading Dock

    618-750 Peoria St, Aurora, CO 80011

    Contact for pricing
    16,308 sqft

    Former plasma center offering multiple offices, large open rooms, and warehouse space with a van-height dock.

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    Move-in Ready Medical Office Suite with Patios
    Move-in Ready Medical Office Suite with Patios

    6650 S Vine St, Centennial, CO 80121

    Contact for pricing
    1,253 sqft

    Move-in ready medical office suite options with in-place utilities for light medical use.

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    Professional Office and Medical Suites
    Professional Office and Medical Suites

    8 West Dry Creek Circle, Littleton, CO 80122

    $22 SF/Yr

    Office and medical-dental space within Highline Professional Center, with convenient access near major roadways and amenities.

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    Medical Office Suites Building
    Medical Office Suites Building

    3955 E Exposition Ave, Denver, CO 80209

    $23 SF/Yr

    Office and medical suites are available with parking on-site and monument signage facing Colorado Blvd.

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    Medical Office Endcap Suite
    Medical Office Endcap Suite

    101 W Hampden Ave Endcap, Englewood, CO 80110

    $25 SF/Yr

    Endcap suite with bright reception, nine private offices/exam rooms, and three restrooms.

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    Aurora Medical Office Space Available
    Aurora Medical Office Space Available

    10680 Del Mar Pkwy, Aurora, CO 80010

    Contact for pricing
    19,400 sqft

    Turn-key medical space in Aurora, available Q1 2026.

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    Centennial Med-Tail Space For Rent
    Centennial Med-Tail Space For Rent

    5657 S Himalaya St 250, Centennial, CO 80015

    $17 SF/Yr
    1.92 AC lot

    Retail frontage space with open layout and private offices.

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    Retail Space in Five-Story Mixed-Use
    Retail Space in Five-Story Mixed-Use

    500 E Hampden Ave, Englewood, CO 80113

    Contact for pricing
    1,958 sqft

    New construction retail space is ready for tenant finishes with dedicated retail parking and prominent on-site signage.

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    Arapahoe County, CO Medical Office Space Market Trends and Statistics

    Explore Medical Office Space leasing options in Arapahoe County, CO with 37 listings featured on our commercial real estate exchange. The current inventory includes 183,334 square feet of properties with an estimated lease value of $268.50.

    Estimated lease rates for Medical Office Space in Arapahoe County, CO begin at $17 SF/Yr, with an average of $24.41 SF/Yr and extend to $43.50 SF/Yr.
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