Simi Valley, CA Medical Office Space for Rent & Lease

Ground-Floor Office Suite with Private Entrance

$4,462/Mo

2,125 SF

Ground-Floor Office Suite with Private Entrance

5775 E Los Angeles Avenue, Simi Valley, CA 93063

Ground-floor suite with private exterior entrance, built-out offices, and dedicated tech room in a multi-tenant office building.

Rare ground‑floor commercial suite with private exterior entrance and direct outside access.
Flexible layout with 2,195 SF of fully built‑out space, divisible into two separate units (including a 700 SF front office space).
Includes 5 private offices, dedicated tech/IT room, and spacious kitchen with seating.
Modern open front office with built‑in wrap‑around workstations and integrated power and cable outlets.
Convenient location near the 118 Freeway with easy access to retail, restaurants, and professional services.

Updated: May 8

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$2,041/Mo

970 SF

Simi Valley Office Suite Available

5775 E Los Angeles Avenue, Simi Valley, CA 93063

Built-out office suite with flexible layout in Simi Valley.

Fully built‑out 970 SF office suite with flexible layout, ready for immediate occupancy.
Includes 4 private offices, reception area, waiting room, and file/storage room.
First month free on a 12‑month lease.
Stunning panoramic views.
Convenient location near the 118 Freeway, retail, restaurants, and professional services.

Updated: May 8

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$2 SF/Yr

9,216 SF

Medical Office Condo First Floor

Entire first floor offers exam rooms and treatment space well-suited for a medical practice with immediate availability.

2876 N. Sycamore Drive, Suite 101, Simi Valley, CA 93065

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1,683 SF

Simi Valley Medical Arts Center

Medical and office spaces available for lease in Simi Valley.

2950 Sycamore Dr, Simi Valley, CA 93065

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7,020 SF

Medical Office Space Sublease

Medical office space for sublease in Simi Valley.

2888 Cochran Street, Simi Valley, CA 93065

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$24 SF/Yr

3,170 SF

Retail/Dental Space Available

Retail and dental spaces available for lease.

2315 Kuehner Dr, Simi Valley, CA 93063

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Based on your search, we've compiled 15 Potential Opportunities for your consideration. Besides 6 Active listings in Simi Valley, CA, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities, and Similar 1 Properties for Sales.

Medical Office Space for Lease in Nearby Cities

Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

$2 SF/Yr

Freestanding Office/Medical Buildings Available

Office and medical buildings for lease or sale in Moorpark.

882 Patriot Dr. |, Moorpark, CA 93021

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$1.90 SF/Yr

1,320 SF

Medical Office Space Available

Medical office space for lease with kitchen and private bathroom.

28720 Roadside Dr, Agoura Hills, CA 91301

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Moorpark Freestanding Office/Medical Building

$2 SF/Yr

4,668 SF

Moorpark Freestanding Office/Medical Building

Freestanding office/medical building in Moorpark, no common areas.

820 Patriot Dr, Moorpark, CA

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Agoura Hills Medical Plaza Location

Located in Conejo Valley, Agoura Hills, Southern California.

29525 Canwood St, Agoura Hills, CA 91301

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Similar Spaces for Sale in Simi Valley, CA

Consider Similar Space for Sale. We found 1 Spaces matching your search parameters.

$3,100,000

25,403 SF

Medical Office Condo First Floor

Medical office condo for sale or lease, entire first floor.

2876 N. Sycamore Drive, Suite 101, Simi Valley, CA 93065

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Potential Development Sites for Consideration

Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

$9,656/Mo

Grand Junction Commercial Land Lease

0.74 acre commercial land for lease in Grand Junction.

Highway 6&50, Grand Junction, CO 81505

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$17,728/Mo

Grand Junction Commercial Land Opportunity

1.36 acre commercial land for lease in Grand Junction.

Sanford Drive, Grand Junction, CO 81505

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$3,600/Mo

El Paso Commercial Land Lease

Commercial land for lease in a strategic El Paso location.

5538 E Paisano Drive, El Paso, TX 79905

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4,000 SF

Office Development Land For Lease

2.43 acres for office development with build-to-suit opportunity.

1323 Strawfloor Drive, Jonesboro, AR 72401

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Simi Valley, CA Medical Office Space Leasing Opportunities Market Analysis

Explore Medical Office Space leasing options in Simi Valley, CA with 6 listings featured on our commercial real estate exchange. The current inventory includes 15,481 square feet of properties with an estimated lease value of $76 SF/Yr.

Estimated lease rates for Medical Office Space in Simi Valley, CA begin at $2 SF/Yr, with an average of $19 SF/Yr and extend to $25 SF/Yr.