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    San Luis Obispo County, CA Medical Office Space for Lease

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    Los Angeles, CA San Diego, CA San Francisco, CA
    14 results
    Turn Key Medical Suite
    Contact for pricing

    Turn Key Medical Suite

    628 California Blvd D-1, San Luis Obispo, CA 93401

    Medical suite with exam rooms, physician's office, and nurse's station.

    • Turn‑key medical suite ready for immediate occupancy.
    • Convenient location with easy access and visibility from Highway 101.
    • Includes 3 exam rooms, 1 physician's office, nurse's station, and private restroom.
    • Sublease available starting July 1, 2026.
    • Potential for a long‑term lease with a qualified tenant.
    Updated: Apr 14
    View details
    Remodeled Office Suite For Rent
    $2,250 /Mo
    930 SF

    Remodeled Office Suite For Rent

    1250 Peach St, San Luis Obispo, CA

    Remodeled office suite with mountain views in Fremont Medical Center.

    • Remodeled suite in the coveted Fremont Medical Center
    • Two offices with separate entrances
    • Deck with views of San Luis Mountain
    • Kitchenette and bathroom included
    • Ample parking available
    Updated: Sep 29, 2025
    View details
    Medical Office Near Sierra Vista
    $3 SF/Yr
    1,300 SF

    Medical Office Near Sierra Vista

    Ground floor medical office space available near Sierra Vista Hospital.

    100 Casa St, San Luis Obispo, CA
    View details
    Downtown Paso Robles Office Building
    $2.00 SF/Yr

    Downtown Paso Robles Office Building

    Office building in Paso Robles' downtown district, suitable for professional/medical uses.

    1030 Vine St |, Paso Robles, CA 93446
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    Downtown San Luis Obispo Office Space
    $1.05 SF/Yr

    Downtown San Luis Obispo Office Space

    First floor office suite suitable for medical or professional use.

    990 Pacific Street |, San Luis Obispo, CA 93401
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    Class A Office Space Available
    $1.85 SF/Yr
    7,197 SF

    Class A Office Space Available

    Ground floor office suite with upgraded finishes and private patios.

    895 Aerovista Pl, San Luis Obispo, CA
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    Prime Nipomo Retail/Service Space
    Contact for pricing
    900 SF

    Prime Nipomo Retail/Service Space

    900 SF retail/service space in Nipomo's commercial corridor.

    541 W Tefft St, Nipomo, CA 93444
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    Medical Office Space Available
    $2 SF/Yr
    1,877 SF

    Medical Office Space Available

    Medical office condo for rent in established medical hub.

    325 Posada Ln, Templeton, CA
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    Arroyo Grande Office Space Available
    $1.75 SF/Yr
    1,748 SF

    Arroyo Grande Office Space Available

    Office suite with exam rooms, private restroom, and patio.

    200 Station Way, Arroyo Grande, CA
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    Renovated Medical/Dental Office Space
    $2 SF/Yr
    1,010 SF

    Renovated Medical/Dental Office Space

    Recently renovated medical/dental office space available for immediate occupancy.

    1223 Higuera St, San Luis Obispo, CA
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    Medical Office Condo Near Hospital
    Contact for pricing
    1,272 SF

    Medical Office Condo Near Hospital

    Medical office condo for lease near Twin Cities Hospital.

    1105 Las Tablas Road, Templeton, CA 93465
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    1288 Morro St, Suite 100
    $1.85 SF/Yr

    1288 Morro St, Suite 100

    Medical Office | San Luis Obispo, CA

    1288 Morro Street, Suite 100 | San Luis Obispo, CA 93401, San Luis Obispo, CA 93401
    View details
    1288 Morro St, Suite 100
    $1.85 SF/Yr

    1288 Morro St, Suite 100

    Medical Office | San Luis Obispo, CA

    1288 Morro Street, Suite 100 | San Luis Obispo, CA 93401, San Luis Obispo, CA 93401
    View details
    Prime Commercial Parcels for Lease
    Contact for pricing

    Prime Commercial Parcels for Lease

    Six improved parcels available for lease in San Luis Obispo.

    250 Tank Farm Rd, San Luis Obispo, CA 93401
    View details
    Based on your search, we've compiled 22 Potential Opportunities for your consideration. Besides 14 Active listings in San Luis Obispo County, CA, we suggest exploring alternatives. Similar 4 Properties for Sales.

    Explore Similar Spaces for Sale in San Luis Obispo County, CA

    Consider Similar Space for Sale. We found 4 Spaces matching your search parameters.

    Downtown Paso Robles Office Building
    $695,000
    1,345 SF

    Downtown Paso Robles Office Building

    Charming office building in downtown Paso Robles with parking.

    1115 Vine Street, Paso Robles, CA 93446
    View details
    Turn-Key Medical Building on Vine
    $900,000

    Turn-Key Medical Building on Vine

    Medical building near downtown Paso Robles, suitable for office uses.

    1036 Vine St, Paso Robles, CA 93446
    View details
    Downtown Paso Robles Office Building
    $920,000

    Downtown Paso Robles Office Building

    Office building in Paso Robles' downtown district, suitable for professional/medical uses.

    1030 Vine St |, Paso Robles, CA 93446
    View details
    Medical Office Condo Near Hospital
    Contact for pricing
    1,272 SF

    Medical Office Condo Near Hospital

    Medical office condo with backup power system near Twin Cities Hospital.

    1105 Road Unit E Unit E, Templeton, CA 93465
    View details

    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

    Grand Junction Commercial Land Lease
    $9,656 /Mo

    Grand Junction Commercial Land Lease

    0.74 acre commercial land for lease in Grand Junction.

    Highway 6&50, Grand Junction, CO 81505
    View details
    Grand Junction Commercial Land Opportunity
    $17,728 /Mo

    Grand Junction Commercial Land Opportunity

    1.36 acre commercial land for lease in Grand Junction.

    Sanford Drive, Grand Junction, CO 81505
    View details
    El Paso Commercial Land Lease
    $3,600 /Mo

    El Paso Commercial Land Lease

    Commercial land for lease in a strategic El Paso location.

    5538 E Paisano Drive, El Paso, TX 79905
    View details
    Highway 72 Corner Lot
    $6,500 /Mo
    1,875 SF

    Highway 72 Corner Lot

    1.6 acre commercial lot for rent on Highway 72.

    30472 Highway 72, Madison, AL 35756
    View details

    San Luis Obispo County, CA Medical Office Space Leasing Opportunities Market Analysis

    Explore Medical Office Space leasing options in San Luis Obispo County, CA with 14 listings featured on our commercial real estate exchange. The current inventory includes 383,850,720 square feet of properties with an estimated lease value of $39 SF/Yr.

    Estimated lease rates for Medical Office Space in San Luis Obispo County, CA begin at $1.85 SF/Yr, with an average of $7 SF/Yr and extend to $29 SF/Yr.
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    Browse Medical Office Space for Lease Near San Luis Obispo, CA

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