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    San Luis Obispo County, CA Medical Office Space for Lease

    15 results
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    Class A Medical Office Space
    Contact for pricing
    1,240 SF

    Class A Medical Office Space

    2 James Way, Pismo Beach, CA 93449

    Premier medical office park with highway visibility in Pismo Beach.

    • Premier Class A medical office park
    • Highway 101 visibility offers excellent exposure.
    • Ample parking for staff and patients.
    • Professional setting ideal for medical practices.
    • Located in Pismo Beach.
    Updated: Jan 16
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    San Luis Obispo Office Space
    $1.75 SF/Yr
    2,159 SF

    San Luis Obispo Office Space

    735 Tank Farm Rd, San Luis Obispo, CA 93401

    Professional office building near airport with upscale finishes and furnishings.

    • Convenient location near the airport and Marigold Center.
    • First‑level suite with open space plan and multiple rooms (offices, kitchen, storage, workout/training).
    • Upscale finishes and furnishings with great common areas.
    • Custom control HVAC system and fully wired for data and phone.
    • Suitable for medical tenant (previously used as a dental office).
    Updated: Nov 14, 2025
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    Class A Medical Office Space
    Contact for pricing
    533 SF

    Class A Medical Office Space

    Premier medical office park with highway visibility in Pismo Beach.

    2 James Way, Pismo Beach, CA 93449
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    Class A Office Space Available
    $0.93 SF/Yr
    7,197 SF

    Class A Office Space Available

    Ground floor office suite with upgraded finishes and private patios.

    895 Aerovista Pl, San Luis Obispo, CA 93401
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    Remodeled Office Suite For Rent
    $2,250 / Mo
    930 SF

    Remodeled Office Suite For Rent

    Remodeled office suite with mountain views in Fremont Medical Center.

    1250 Peach St, San Luis Obispo, CA 93401
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    Renovated Medical/Dental Office Space
    $2 SF/Yr
    1,010 SF

    Renovated Medical/Dental Office Space

    Recently renovated medical/dental office space available for immediate occupancy.

    1223 Higuera St, San Luis Obispo, CA 93401
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    Medical Office Space Available
    $2 SF/Yr
    1,877 SF

    Medical Office Space Available

    Medical office condo for rent in established medical hub.

    325 Posada Ln, Templeton, CA 93465
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    Medical Office Space Available
    $1.05 SF/Yr
    1,633 SF

    Medical Office Space Available

    First floor medical office space with examination rooms for rent.

    1288 Morro St, San Luis Obispo, CA 93401
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    Dental Office Space Available
    Contact for pricing

    Dental Office Space Available

    1,332 SF office space suitable for dental practice.

    106 Gateway Center Dr, Paso Robles, CA 93446
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    Medical Office Near Sierra Vista
    $3 SF/Yr
    1,300 SF

    Medical Office Near Sierra Vista

    Ground floor medical office space available near Sierra Vista Hospital.

    100 Casa St, San Luis Obispo, CA 93405
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    Downtown San Luis Obispo Office Space
    $1.05 SF/Yr
    25 SF

    Downtown San Luis Obispo Office Space

    First floor office suite suitable for medical or professional use.

    990 Pacific St, San Luis Obispo, CA 93401
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    Medical Suite Near Highway 101
    Contact for pricing

    Medical Suite Near Highway 101

    Medical suite available for rent near Highway 101.

    620 California G, San Luis Obispo, CA 93401
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    Arroyo Grande Office Space Available
    Contact for pricing
    1,748 SF

    Arroyo Grande Office Space Available

    Office suite with exam rooms, private restroom, and patio.

    200 Station Way, Arroyo Grande, CA 93420
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    Downtown Paso Robles Office Building
    $2.00 SF/Yr
    2 SF

    Downtown Paso Robles Office Building

    Office building in Paso Robles' downtown district, suitable for professional/medical uses.

    1030 Vine St, Paso Robles, CA 93446
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    Medical Office Condo Near Hospital
    Contact for pricing
    1,272 SF

    Medical Office Condo Near Hospital

    Medical office condo for lease near Twin Cities Hospital.

    1105 Las Tablas Rd, Templeton, CA 93465
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    Based on your search, we've compiled 25 Potential Opportunities for your consideration. Besides 15 Active listings in San Luis Obispo County, CA, we suggest exploring alternatives. Similar 10 Properties for Sales.

    Explore Similar Spaces for Sale in San Luis Obispo County, CA

    Consider Similar Space for Sale. We found 10 Spaces in Nearby Locations matching your search parameters.

    Versatile Medical/Professional Office Space
    $749,000
    1,751 SF

    Versatile Medical/Professional Office Space

    Adaptable space for medical or professional office uses.

    1577 El Camino Real, Arroyo Grande, CA 93420
    View details
    Commercial/Residential Opportunity in Paso Robles
    $1,099,000
    1,290 SF

    Commercial/Residential Opportunity in Paso Robles

    Two neighboring parcels in downtown Paso Robles with commercial/residential potential.

    1545 Park St, Paso Robles, CA 93446
    View details
    Downtown Paso Robles Office Building
    $695,000
    1,345 SF

    Downtown Paso Robles Office Building

    Charming office building in downtown Paso Robles with parking.

    1115 Vine St, Paso Robles, CA 93446
    View details
    Medical Office Condos For Sale
    $395,000

    Medical Office Condos For Sale

    Two medical office condos located next to Twin Cities Hospital.

    1050 Las Tablas Rd, Templeton, CA 93465
    View details
    Turn-Key Medical Building on Vine
    $900,000

    Turn-Key Medical Building on Vine

    Medical building near downtown Paso Robles, suitable for office uses.

    1036 Vine St, Paso Robles, CA 93446
    View details
    Santa Rosa Professional Building For Sale
    $2,175,000

    Santa Rosa Professional Building For Sale

    Two-unit medical/general office building constructed in 1962.

    1338 Santa Rosa St, San Luis Obispo, CA 93401
    View details
    Medical/Professional Office Building For Sale
    $1,790,000

    Medical/Professional Office Building For Sale

    Medical/Professional office building with five suites, excellent visibility.

    8655 Morro Rd, Atascadero, CA 93422
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    Medical Office Space Available
    $2,830,000

    Medical Office Space Available

    Prime medical office space with high visibility in San Luis Obispo.

    689 Tank Farm Rd, San Luis Obispo, CA 93401
    View details
    Downtown Paso Robles Office Building
    $920,000
    2 SF

    Downtown Paso Robles Office Building

    Office building in Paso Robles' downtown district, suitable for professional/medical uses.

    1030 Vine St, Paso Robles, CA 93446
    View details

    San Luis Obispo County, CA Medical Office Space Leasing Opportunities Market Analysis

    Explore Medical Office Space leasing options in San Luis Obispo County, CA with 25 listings featured on our commercial real estate exchange. The current inventory includes 702,753,480 square feet of properties with an estimated lease value of $44 SF/Yr.

    Estimated lease rates for Medical Office Space in San Luis Obispo County, CA begin at $0.93 SF/Yr, with an average of $4 SF/Yr and extend to $29 SF/Yr.
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    Medical Office Space by market

    Browse Medical Office Space for Lease Near San Luis Obispo, CA

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