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    Hesperia, CA Medical Office Space for Lease

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    Main Street Professional Center Unit
    $2,500 / Mo

    Main Street Professional Center Unit

    17450 Main St E, Hesperia, CA 92345

    Professional center unit with exam rooms, kitchenette, and private office.

    • Convenient location on Main Street with easy access to I Ave and I‑15.
    • Features ±1,440 square feet including a front area, 3 bathrooms, exam rooms, kitchenette, and a private office.
    • Front and rear doors offer separate access for patients and staff.
    • Located in a mixed‑use area, walk to food, shopping, and bus stops.
    • Part of the Main Street Professional Center with mixed medical uses.
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    Retail Shell Building For Lease
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    Retail Shell Building For Lease

    15634 Main St, Hesperia, CA 92345

    Under construction retail shell building with multiple units for lease.

    • New construction retail shell building, estimated completion July‑Aug 2025
    • Total of 6403 Sq ft rentable area with 5 units
    • Units suitable for retail, office, or medical spaces
    • Units A (1692 Sq ft) and E (1770 Sq ft) are ideal for restaurants
    • Variety of unit sizes available: 1692, 1770, 992, 1009, and 940 Sq ft
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    Medical Office Space Available
    Contact for pricing

    Medical Office Space Available

    Private office space in medical building with exterior access.

    15462 Main St, Hesperia, CA 92345
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    Medical Office Space Available
    Contact for pricing

    Medical Office Space Available

    Private office space in medical building with exterior access.

    15462 Main St, Hesperia, CA 92345
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    Based on your search, we've compiled 10 Potential Opportunities for your consideration. Besides 4 Active listings in Hesperia, CA, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities, and Similar 2 Properties for Sales.

    Explore Medical Office Space for Lease in Nearby Cities

    Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

    Victorville Commercial Multi-Use Property
    Contact for pricing
    211,190 SF

    Victorville Commercial Multi-Use Property

    Prime Victorville location, large spaces available.

    0 2Nd Ave, Victorville, CA 92395
    View details
    Wimbledon Village Office Space
    Contact for pricing
    1,728 SF

    Wimbledon Village Office Space

    Victorville Office Suites - 1,728 SF Available

    12380 Hesperia Rd, Victorville, CA 92395
    View details
    Versatile Space for Healthcare Providers
    $1.00 SF/Yr

    Versatile Space for Healthcare Providers

    Well-maintained 3,000 SF suite ideal for healthcare or professional offices.

    18031 Us Highway 18, Apple Valley, CA 92307
    View details
    Medical Office Space with Veranda
    Contact for pricing

    Medical Office Space with Veranda

    Second floor medical office space with a large private veranda.

    15099 Kamana Rd, Apple Valley, CA 92307
    View details

    Explore Similar Spaces for Sale in Hesperia, CA

    Consider Similar Space for Sale. We found 2 Spaces in Nearby Locations matching your search parameters.

    Hesperia Office Investment
    $2,626,000
    9,135 SF

    Hesperia Office Investment

    Prime location, high occupancy, strong tenant.

    15255 Bear Valley Rd, Hesperia, CA 92345
    View details
    Hesperia Medical Office Building
    $1,280,000
    6,000 SF

    Hesperia Medical Office Building

    6,000 SF Medical Office, High NOI

    17151 Main St, Hesperia, CA 92345
    View details

    Hesperia, CA Medical Office Space Leasing Opportunities Market Analysis

    Explore Medical Office Space leasing options in Hesperia, CA with 6 listings featured on our commercial real estate exchange. The current inventory includes 0 square feet of properties with an estimated lease value of $0.00 SF/Yr.

    Estimated lease rates for Medical Office Space in Hesperia, CA begin at $0.00 SF/Yr, with an average of $0.00 SF/Yr and extend to $0.00 SF/Yr.
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