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Freestanding Flex Space with Lab Improvements
For Sale
$23,500,000

4650 Overland Ave, San Diego, CA 92123

Highly improved flex facility with laboratories, clean rooms, offices, warehouse areas, and employee support amenities.

Property Size56,159 SF
Price / SF$418.45
Days on Market8

Property Features for 4650 Overland Ave

General Information

Standard status Active
Size 56,159 SF
Property subtype Industrial

Site & Location

Highway Access Yes
Road Access Yes

Building Details

Buildings 1
Building Size 56,159 SF
Listing Agency: San Diego
Listed By: Bob Mooney · License #00836061
Source: Colliers
Added: Aug 23 Changed: Aug 29 Last Checked: Aug 29 at 10:29PM

Displayed information is deemed reliable but is not guaranteed and should be independently verified. All listing content including descriptions, pricing, images are the copyrighted material of San Diego

Investment Insights

Based on property information with market context.

This 56,159-square-foot freestanding flex facility combines specialized work areas with adaptable office and warehouse components. The interior includes laboratories, clean rooms, conference rooms, private offices, open bullpen areas, a kitchen, lunchroom, lounge, patios, and skylights. Warehouse improvements include multiple dock loading doors, substantial clear height, locker rooms, and showers, supporting a range of operational layouts.

The property is located at 4650 Overland Avenue within the Spectrum Center in Kearny Mesa, San Diego. Interstates 15, 8, and 805 are nearby, along with the 163 and 52 freeways. These routes connect to San Diego within a five-minute drive and reach the Inland Empire and Los Angeles in under two hours. San Diego International Airport is 9.2 miles away, while the surrounding area offers walkable access to a broad range of amenities.

Key Highlights

  • 56,159‑square‑foot freestanding flex building at 4650 Overland Avenue
  • Laboratories, clean rooms, conference rooms, offices, bullpen areas, and employee lounge spaces
  • Warehouse areas with multiple dock loading doors and substantial clear height

Financial Insights

Estimated NOI and Cap Rate

NOI = area × lease_rate × (100 − vacancy) / 100 × (1 − expense_ratio). Net Operating Income — what the owner takes home each year before mortgage payments and income tax. Effective rent (asking rent minus vacancy losses) minus operating costs (taxes, insurance, maintenance, management).
NOI / Yr
$814,755
Cap rate = NOI / list price × 100. Capitalization rate — annual return on a fully cash purchase, before financing. NOI divided by price. Higher means more income per dollar invested, but usually also more risk or older condition. 5–8% is typical for stabilized commercial property; double digits often signal distressed deals.
Cap Rate
3.47%
Suggested Prices Based on Cap Rates Cap rates vary significantly by property type, market, and asset quality. Typical U.S. stable-market ranges: Multifamily — 4.5% to 6.5% (Class A in primary markets often sub-5%; Class C in secondary markets 6%+) Industrial / Logistics — 5.0% to 7.0% (compressed heavily in recent years due to e-commerce demand) Office — 6.5% to 9%+ (wide spread post-2020; CBD Class A vs. suburban Class B varies dramatically) Retail — 5.5% to 8.5% (grocery-anchored on the low end, unanchored strip centers higher) Hospitality / Hotels — 7.5% to 10%+ (higher due to operational risk) Self-Storage — 5.5% to 7.5% Medical Office — 6.0% to 7.5% Net Lease (single tenant, credit) — 5.0% to 7.0% depending on tenant credit and lease term Rules of thumb: Primary markets (NYC, SF, LA, Boston, DC) trade at lower cap rates than secondary/tertiary markets, often by 100–200 bps (bps, aka basis points; 1 bp = 0.01%). Class A assets trade ~50–150 bps tighter than Class B, and Class B tighter than Class C. Cap rates move inversely with price — a lower cap rate means a higher price for the same NOI. Spread to the 10-year Treasury is a common benchmark; historically 200–400 bps over the 10-year.
Cap Rate 5%
$16,295,100 $16.3M
Cap Rate 7%
$11,639,357 $11.6M
Cap Rate 9%
$9,052,833 $9.1M
Market Conditions
NOI Build-Up for 56,159 SF Vacancy — income lost from leasable area expected to sit empty during the year, subtracted from gross rent. EGI (Effective Gross Income) — gross rent minus vacancy losses, the realistic income before paying operating costs. OpEx (Operating Expenses) — recurring costs to operate the property (property tax, insurance, utilities, maintenance, management); excludes financing and capital improvements. NOI (Net Operating Income) — income a property generates after operating costs but before financing and taxes.
Gross rent
$1.35M $24.00/SF
− Vacancy
−$94.3K −$1.68/SF
EGI
$1.25M $22.32/SF
− OpEx
−$438.7K −$7.81/SF
NOI
$814.8K $14.51/SF
Area
San Diego, CA
Vacancy
7.00%
Lease Rate
$24.00 /SF/Yr
Expense Ratio
35.00%
Simulate Cap Rate and NOI
Suggested Prices Based on Cap Rates Cap rates vary significantly by property type, market, and asset quality. Typical U.S. stable-market ranges: Multifamily — 4.5% to 6.5% (Class A in primary markets often sub-5%; Class C in secondary markets 6%+) Industrial / Logistics — 5.0% to 7.0% (compressed heavily in recent years due to e-commerce demand) Office — 6.5% to 9%+ (wide spread post-2020; CBD Class A vs. suburban Class B varies dramatically) Retail — 5.5% to 8.5% (grocery-anchored on the low end, unanchored strip centers higher) Hospitality / Hotels — 7.5% to 10%+ (higher due to operational risk) Self-Storage — 5.5% to 7.5% Medical Office — 6.0% to 7.5% Net Lease (single tenant, credit) — 5.0% to 7.0% depending on tenant credit and lease term Rules of thumb: Primary markets (NYC, SF, LA, Boston, DC) trade at lower cap rates than secondary/tertiary markets, often by 100–200 bps (bps, aka basis points; 1 bp = 0.01%). Class A assets trade ~50–150 bps tighter than Class B, and Class B tighter than Class C. Cap rates move inversely with price — a lower cap rate means a higher price for the same NOI. Spread to the 10-year Treasury is a common benchmark; historically 200–400 bps over the 10-year.
Cap Rate 5%
$16,295,100
Cap Rate 7%
$11,639,357
Cap Rate 9%
$9,052,833

Alternative Uses

Best Use
Flex RnD
$11.64M
$10.18M – $13.58M (±1% cap)
NOI $814,755 @ 7.0% cap · market cap 3.47%
Second Best
Warehouse
$11.52M
$10.08M – $13.44M (±1% cap)
NOI $806,476 @ 7.0% cap · market cap 3.43%
Theoretical Best
Specialty Retail
$22.18M
$19.41M – $25.88M (±1% cap)
NOI $1,552,684 @ 7.0% cap · market cap 6.61%
Zoning and permitted uses should be independently verified with authorities.

Property Analytics

Current Use

MabPlex USA, Inc Corporate Office

Suggested Use

Top Pick Grocery & Convenience Store Butcher (Bike/Boat/Book/etc) Store Pet Grooming Service Storage Facility Clothing & Fashion Store

Score = modeled unmet demand for each use within ~1 mi (higher = bigger opportunity). Zoning and permitted uses should be independently verified with local authorities.

Lease Details

Yes
Highway access
Yes
Paved road access

Location Intelligence

Trade Area within ½ mile

1,943
Businesses Nearby
Well-served
Demand for This Use

Demographics for 92123, CA

30,937
Population
13,108
Households
2.4
Avg Household Size
34
Median Age
48%
College-Educated
93%
High-School Grad
8.6 sq mi
ZIP Area
3,597
Density / Sq Mi
$121,856
Median Household Income
$55,111
Median Earnings
$2,798
Median Rent
$799,600
Median Home Value

Market

Vacancy Rate% for Industrial in San Diego, CA

5.1% 2019
5% 2020
2.5% 2021
2.4% 2022
4.4% 2023
6.5% 2024
7.2% 2025
Rey
Questions? Ask Rey
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Frequently Asked Questions

What type of property is this?
Flex space - Highly improved flex facility with laboratories, clean rooms, offices, warehouse areas, and employee support amenities.
Where is this flex space located?
The property is located at 4650 Overland Ave San Diego, CA.
What is the asking price?
The asking price for this property is $23,500,000.
What are key features of this property?
This property features: 56,159‑square‑foot freestanding flex building at 4650 Overland Avenue; Laboratories, clean rooms, conference rooms, offices, bullpen areas, and employee lounge spaces; Warehouse areas with multiple dock loading doors and substantial clear height
More about this property
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