Medical Building on Hilton
For Lease
$17 SF/Yr
4101 Main St Suites E & F, Hilton Head Island, SC 29926
Stand-alone medical building for lease on Hilton Head Island.
Space Size1,286 SF - 3,600 SF
Days on Market171
Property Features for 4101 Main St Suites E & F
General Information
Standard status
Active
Size
1,286 SF - 3,600 SF
Class
A
Property subtype
Medical & Office Building
Lease Term
NNN
Building Details
Building Size
3,600 SF
Year Built
2001
Spaces For Lease
at 4101 Main St Suites E & F Contact us- Size
- 1,286 SF
- Type
- Office Building
- Term
- Negotiable
4101 Main Street $17/SF/Yr
- Size
- 2,314 SF
- Type
- Medical
- Term
- Negotiable
4101 Main Street $19/SF/Yr
- Size
- 3,600 SF
- Term
- Negotiable
4101 Main Street $19/SF/Yr
Listing Agency:
NAI Carolina Chapter
(843) 247-2470
Listed By:
Baker Wilkins · License #31069
(843) 247-2470
Source:
Naicarolinacharter
Added: Mar 5
Changed: Aug 8
Last Checked: Aug 22 at 5:03AM
Displayed information is deemed reliable but is not guaranteed and should be independently verified. All listing content including descriptions, pricing, images are the copyrighted material of NAI Carolina Chapter
Investment Insights
Based on property information with market context.
This stand-alone medical office building is located on Main Street on the north end of Hilton Head Island, just off Highway 278. The property offers convenient access to Hilton Head Hospital, the surrounding professional area, and nearby Bluffton. The ground-floor layout features multiple exam rooms, a waiting area, and private offices. Plumbing is in place to support additional exam or treatment rooms. Recently vacated, the building is ready for immediate tenant improvements or occupancy, making it suitable for medical or wellness users seeking a professional island location. The intended use of the property is for medical purposes.
Key Highlights
- Stand‑alone medical building, ideal for medical or wellness users.
- Prime location on Main Street, North End of Hilton Head Island, with easy access to Highway 278.
- Convenient access to Hilton Head Hospital and surrounding professional area.
Property Analytics
Property Profile
Current Use
Lease Details
NNN (Triple Net)
Lease Type
$2.55 /SF/Yr
CAM
Location Intelligence
Trade Area within ½ mile
829
Businesses Nearby
Balanced
Demand for This Use
Explore this area
Business Placement
Demographics for 29926, SC
24,832
Population
12,642
Households
2
Avg Household Size
56
Median Age
52%
College-Educated
91%
High-School Grad
28.7 sq mi
ZIP Area
865
Density / Sq Mi
$101,573
Median Household Income
$44,019
Median Earnings
$1,448
Median Rent
$600,300
Median Home Value
Market
Vacancy Rate% for Office in South region
Questions? Ask Rey
Realmo’s AI knows this listing — price, zoning, demand, history. Ask anything.
Frequently Asked Questions
What type of property is this?
Medical Office Space - Stand-alone medical building for lease on Hilton Head Island.
Where is this medical office space located?
The property is located at 4101 Main St Suites E & F Hilton Head Island, SC.
What is the lease rate?
The lease rate is $17 SF/Yr.
What are key features of this property?
This property features: Stand‑alone medical building, ideal for medical or wellness users.; Prime location on Main Street, North End of Hilton Head Island, with easy access to Highway 278.; Convenient access to Hilton Head Hospital and surrounding professional area.
