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    Hillsboro, MO Commercial Real Estate for Sale

    7 results
    List
    Map
    Hillsboro Retail with Highway Frontage
    Pending
    $299,000
    0.27 Acres

    Hillsboro Retail with Highway Frontage

    10550 Business 21, Hillsboro, MO 63050

    Retail property in Hillsboro with highway frontage and recent updates.

    • High‑traffic corner location with highway frontage
    • New roof installed in 2022
    • New furnace and AC
    • Updated flooring and fresh paint in 2019
    • Three offices (or two offices and a conference room)
    Updated: Apr 29, 2025
    View details
    Hillsboro Retail Center Investment
    Pending
    $950,000
    19,936 SF

    Hillsboro Retail Center Investment

    10814 Business 21, Hillsboro, MO 63050

    Fully occupied retail center in Hillsboro, MO with 10% cap rate.

    • 10% Cap Rate: Provides a significant return on investment
    • 100% Occupied: Ensures immediate cash flow
    • Well‑Established Anchor Tenant: Local favorite Mexican restaurant occupies 50% of the main level
    • Recent Improvements: Seller added marquee signs and paved/striped the lower parking lot
    • Fully Accessible Lower Level: Adds significant usable space to the 9968 sq ft main level
    Updated: Dec 29, 2025
    View details
    Hillsboro Commercial Property - Main Street
    $437,000
    0.51 Acres

    Hillsboro Commercial Property - Main Street

    Versatile Property, Prime Location, High Visibility

    114 Main St, Hillsboro, MO 63050
    View details
    Hillsboro Commercial Investment Opportunity
    $399,900
    0.25 Acres

    Hillsboro Commercial Investment Opportunity

    Fully Leased, Multi-Tenant Building, Great ROI

    304 Locust St, Hillsboro, MO 63050
    View details
    Historic Hillsboro Commercial Gem
    $330,000
    0.30 Acres

    Historic Hillsboro Commercial Gem

    Multi-use building, prime downtown location.

    411 Maple St, Hillsboro, MO 63050
    View details
    Prime Hillsboro Office Building
    $437,000
    2,772 SF

    Prime Hillsboro Office Building

    Historic Charm, Modern Updates, High Visibility

    114 Main St, Hillsboro, MO 63050
    View details
    Hillsboro Retail Property for Sale
    $2,200,000
    9,641 SF

    Hillsboro Retail Property for Sale

    9,641 SF retail property available in Hillsboro, Missouri.

    10333 Business 21, Hillsboro, MO 63050
    View details
    Based on your search, we've compiled 225 Potential Opportunities for your consideration. Besides 7 Active listings in Hillsboro, MO, we suggest exploring several alternatives: 4 properties in Nearby Cities, and similar 213 Off-Market properties to explore as potential leads, plus 1 Land Listings that present a potential for development.

    Explore Opportunities in Nearby Cities

    Here are 4 Similar properties we found in Nearby Locations for your consideration.

    Spacious Multi-Home Property on 5.4 Acres
    $425,000
    2,588 SF

    Spacious Multi-Home Property on 5.4 Acres

    Three homes on 5.4 acres, ideal for homesteading or rental income.

    1818 Hunter Rd, Festus, MO 63028
    View details
    De Soto Church Building on 5+ Acres
    $399,900
    3,739 SF

    De Soto Church Building on 5+ Acres

    Church building with spacious sanctuary and high-visibility location.

    4041 Maple Downs Ct, De Soto, MO 63020
    View details
    Festus Multi-Tenant Property For Sale
    Pending
    $1,150,000
    3,420 SF

    Festus Multi-Tenant Property For Sale

    Multi-tenant property on 12 acres near Hwy 67.

    3041 Meyer Rd, Festus, MO 63028
    View details
    De Soto Retail Business Opportunity
    $850,000
    15,500 SF

    De Soto Retail Business Opportunity

    Own a business and a piece of history!

    400 S Main St, De Soto, MO 63020
    View details

    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

    Hillsboro Land Near City Hall
    Pending
    $426,900
    0.51 Acres

    Hillsboro Land Near City Hall

    Versatile half-acre lot in prime Hillsboro location.

    114 Main St, Hillsboro, MO 63050
    View details

    Explore Off-Market Properties in Hillsboro, MO

    Consider similar Off-Market properties in Hillsboro, MO. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

    21 Old Rte

    21 Old Rte

    Commercial real estate • 7.13 Acres
    Value Estimation by Request
    21 Old Rte, Hillsboro, MO 63050
    View details
    10616 Business 21

    10616 Business 21

    Commercial real estate • 1.34 Acres
    Value Estimation by Request
    10616 Business 21, Hillsboro, MO 63050
    View details
    411 Maple St

    411 Maple St

    Commercial real estate • 0.30 Acres
    Value Estimation by Request
    411 Maple St, Hillsboro, MO 63050
    View details
    8719 Old State Route 21

    8719 Old State Route 21

    Commercial real estate • 43.00 Acres
    Value Estimation by Request
    8719 Old State Route 21, Hillsboro, MO 63050
    View details
    10430 Business 21

    10430 Business 21

    Commercial real estate • 2.04 Acres
    Value Estimation by Request
    10430 Business 21, Hillsboro, MO 63050
    View details
    Karen Dr

    Karen Dr

    Commercial real estate • 0.41 Acres
    Value Estimation by Request
    Karen Dr, Hillsboro, MO 63050
    View details
    10303 Business 21

    10303 Business 21

    DISTRIBUTION WAREHOUSE • 0.80 Acres
    Value Estimation by Request
    10303 Business 21, Hillsboro, MO 63050-3587
    View details
    Hillsboro, MO 63050

    Hillsboro, MO 63050

    MANUFACTURING (LIGHT) • 1,920 SF
    Value Estimation by Request
    Hillsboro, MO 63050
    View details
    11200 State Rte 21

    11200 State Rte 21

    DISTRIBUTION WAREHOUSE • 3,200 SF
    Value Estimation by Request
    11200 State Rte 21, Hillsboro, MO 63050-5011
    View details
    11356 State Rte 21

    11356 State Rte 21

    MINI-WAREHOUSE, STORAGE • 0.93 Acres
    Value Estimation by Request
    11356 State Rte 21, Hillsboro, MO 63050-5012
    View details
    10662 Business 21

    10662 Business 21

    MINI-WAREHOUSE, STORAGE • 1,800 SF
    Value Estimation by Request
    10662 Business 21, Hillsboro, MO 63050
    View details
    Hillsboro, MO 63050

    Hillsboro, MO 63050

    MINI-WAREHOUSE, STORAGE • 36,030 SF
    Value Estimation
    $1,170,000
    Hillsboro, MO 63050
    View details
    9601 Old State Rte 21

    9601 Old State Rte 21

    MINI-WAREHOUSE, STORAGE • 7,080 SF
    Value Estimation by Request
    9601 Old State Rte 21, Hillsboro, MO 63050-5703
    View details
    9334 State Rd Bb

    9334 State Rd Bb

    MANUFACTURING (LIGHT) • 25,514 SF
    Value Estimation
    $620,000
    9334 State Rd Bb, Hillsboro, MO 63050-2308
    View details
    8811 Old State Rte 21

    8811 Old State Rte 21

    MINI-WAREHOUSE, STORAGE • 4.55 Acres
    Value Estimation by Request
    8811 Old State Rte 21, Hillsboro, MO 63050-2054
    View details
    6867 State Rd Y Y

    6867 State Rd Y Y

    DISTRIBUTION WAREHOUSE • 3.35 Acres
    Value Estimation by Request
    6867 State Rd Y Y, Hillsboro, MO 63050-4033
    View details
    11383 State Rte 21

    11383 State Rte 21

    MINI-WAREHOUSE, STORAGE • 12,000 SF
    Value Estimation by Request
    11383 State Rte 21, Hillsboro, MO 63050
    View details

    Hillsboro, MO Commercial Real Estate Investment Opportunities Market Analysis

    Explore 199 commercial real estate investment opportunities in Hillsboro, MO with 7 listings featured on our commercial real estate marketplace. The current inventory includes 38,771,952 square feet of properties with an estimated value of $51,689,520.

    Estimated prices for commercial real estate in Hillsboro, MO begin at $34,900, with an average of $321,052 and extend to $1,062,000.

    In Hillsboro, MO, current investment values show:

    • Retail properties positioned at $348,034
    • Office Properties & Spaces measuring $311,763
    • Other office properties assessed at $294,513
    • Individual retail properties calculated at $372,757
    List
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    Browse Commercial real estate for Sale Near Hillsboro, MO

    Popular Searches in Hillsboro, MO

    Most Searched ZIP Codes in Hillsboro, MO

    • 63050
    • 63016

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