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South San Francisco Office Space
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4000 Shoreline Court, South San Francisco, CA 94080

Office and medical space available for lease in South San Francisco.

Space SizeContact for details
Days on Market274

Property Features for 4000 Shoreline Court

General Information

Standard status Active
Property subtype LifeSciences
Listing Agency: CBRE | San Francisco
Listed By: Dino Perazzo · License #01220613
Source: Cbre
Added: Nov 22, 2025 Changed: Aug 23 Last Checked: Aug 22 at 8:08AM

Displayed information is deemed reliable but is not guaranteed and should be independently verified. All listing content including descriptions, pricing, images are the copyrighted material of CBRE | San Francisco

Investment Insights

Based on property information with market context.

This property offers office and medical space for rent, encompassing a total area of 24581 square feet. It is located in South San Francisco, California.

Key Highlights

  • Office and medical space available
  • Located in South San Francisco

Property Analytics

Current Use

Capgemini (Bike/Boat/Book/etc) Store Kezar Life Sciences Corporate Office Tizona Therapeutics Corporate Office PC Gamer Publishing House

Suggested Use

Top Pick Real Estate Agency Building Supply Auto Repair Shop HVAC Service Pharmacy Garden Center

Score = modeled unmet demand for each use within ~1 mi (higher = bigger opportunity). Zoning and permitted uses should be independently verified with local authorities.

Lease Details

NNN (Triple Net)
Lease Type

Location Intelligence

Trade Area within ½ mile

585
Businesses Nearby

Demographics for 94080, CA

66,592
Population
23,364
Households
2.9
Avg Household Size
40
Median Age
40%
College-Educated
86%
High-School Grad
10.2 sq mi
ZIP Area
6,529
Density / Sq Mi
$135,966
Median Household Income
$61,138
Median Earnings
$2,840
Median Rent
$1,159,500
Median Home Value

Market

Vacancy Rate% for Office in West region

11% 2019
14.1% 2020
15.5% 2021
17.2% 2022
19.9% 2023
21% 2024
20.8% 2025
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Frequently Asked Questions

What type of property is this?
Office units - Office and medical space available for lease in South San Francisco.
Where is this office units located?
The property is located at 4000 Shoreline Court South San Francisco, CA.
What are key features of this property?
This property features: Office and medical space available; Located in South San Francisco
More about this property
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