101 North Main Street, Greenville, SC 29601

Listing office CBRE | Greenville c***@cbre.com Show Phone

Listing date Mar 25, 2026

Source Cbre

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Overview

Located on ONE City Plaza in the heart of Greenville's downtown, this 16-story building offers approximately 195,907 square feet of total space. The property is pedestrian-friendly, providing convenient access to over 120 restaurants, 100 retailers, more than six hotels, and downtown attractions such as Falls Park and the Swamp Rabbit Trail. Amenities include a fitness center equipped with locker rooms and showers, and an on-site coffee shop. Parking is available in adjacent city garages, with direct access to the garages from the third floor. This building was one of the first in South Carolina to receive a WIRED Certification.

Suggested Use

Law Firm Big Box & Wholesale Store Garden Center Department Store Building Supply HVAC Service Discount Store Furniture & Home Goods Bed & Breakfast Cafe & Coffee Shop

Zoning and permitted uses should be independently verified with local authorities.

Location Insight

• Map
• Local Demand

City

Greenville

County

Greenville

State

South Carolina

Longitude

-82.255668

Latitude

34.7375573

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FAQs

What type of property is this?

Office building - Office space for rent in downtown Greenville with amenities.

Where is this office building located?

The property is located at 101 North Main Street Greenville, SC.

What is the lease rate?

The lease rate is $36 SF/Yr.

What are key features of this property?

This property features: Located in the heart of Greenville's award‑winning downtown with pedestrian access to numerous restaurants, retailers, hotels, and attractions.; Boasting ±195,907 SF Total Building with 16 Floors.; Direct access to parking garages from the third floor.