Winston Salem, NC Industrial properties for Lease: Rent Manufacturing Spaces Near You

Updated: Jun 2

Renovated Office and Lab Flex Buildings

3041-3051 TRENWEST DRIVE WINSTON SALEM NC 27103, Winston Salem, NC 27103

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6,430 sqft

Two buildings with updated HVAC, plumbing, electrical, and roof (3041 Trenwest Dr and 3051 Trenwest Dr).
3041 Trenwest Dr: 3,416 +/- SF professional office, renovated in 2025.
3051 Trenwest Dr: 6,430 +/- SF lab/production with staff support, renovated in 2018.
Prime location just off S Stratford Rd and within 2 miles of Novant Health Forsyth Med. Center (9,320 employees).
Within 2 miles of Wake Forest Baptist Med. Center (14,000 employees).

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Updated: May 20

Flex Office and Lab Buildings

3041-3051 Trenwest Dr, Winston Salem, NC 27103

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9,846 sqft

3041 Trenwest Dr offers 3,416 +/- SF professional office space, renovated in 2025
3051 Trenwest Dr offers 6,430 +/- SF for lab/production with staff support, renovated in 2018
Two renovated flex buildings totaling 9,846 +/- SF with both professional office and lab/production use

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Industrial Space in Whitaker Park

4015 Reynolds Ct, Winston Salem, NC

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20,000 sqft 2.86 AC lot

Industrial space for lease in North Winston, available Q3 2026.

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Based on your search, we've compiled 8 Potential Opportunities for your consideration. Besides 3 Active listings in Winston Salem, NC, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities, and Similar 1 Properties for Sales.

Industrial properties for Lease in Nearby Cities

Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

NC, Winston-Salem - W Third St

102 3Rd St, Winston-salem, NC 27101

11 available spaces from 11 to 1,292 sqft

$129-$4,498/Mo per office

Flexible workspace in NC, Winston-Salem - W Third St. Book a tour & get info

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Modern Industrial/Flex Space Available

340 Forum Parkway, Rural Hall, NC 27045

$12 SF/Yr

Exceptional Industrial/Flex Space units in Rural Hall, NC for rent.

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Modern Industrial/Flex Space Available

320 Forum Parkway, Rural Hall, NC 27045

$12 SF/Yr

Customizable industrial/flex space with ample parking and high ceilings.

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New Construction Flex Space Available

3947 West Point Blvd, Winston-salem, NC

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17,600 sqft 12.16 AC lot

New construction flex space in West Point Business Park.

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Similar Spaces for Sale in Winston Salem, NC

Consider Similar Space for Sale. We found 1 Spaces matching your search parameters.

Two-Story Flex Space with Bay Door

610 N. Liberty Street, Winston Salem, NC 27101

$1,250,000

8,374 sqft

Renovated two-level commercial space configured for gym operations with on-site parking and shower-equipped restrooms.

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Winston Salem, NC Industrial properties Lease Rates & Market Statistics

Explore 3 Industrial properties for lease in Winston Salem, NC on Realmo, a commercial real estate exchange covering the Winston Salem area. The current inventory totals 36,276 square feet of properties.

Winston Salem accounts for 16% of the 19 industrial properties currently available across Forsyth County, where nearby markets include Winston-Salem and Kernersville.

How to lease industrial property in Winston Salem, NC

Define your operational specs. List the requirements that can't be changed later: clear height, dock doors, floor load capacity, column spacing, and 3-phase power for equipment.

Position for your supply chain. Use Location Intelligence to compare Winston Salem, NC submarkets by highway, rail, and port access. Infill sites near urban cores cost more but win last-mile delivery.

Verify zoning and building condition. Confirm your use (manufacturing, distribution, storage) is permitted, and inspect truck court depth (120+ ft. for modern trailers), HVAC, and roof condition.

Order an environmental assessment. Request a Phase I environmental report. Without protective lease language, tenants can inherit liability for contamination left by prior industrial users.

Model the NNN economics. Industrial leases are typically triple net with 2–4% annual escalations. Calculate total occupancy cost, not just base rent, using the Lease Calculator.

Negotiate term, TI, and expansion rights. Standard terms run 3–7 years. Trade a longer commitment for a bigger TI allowance and secure renewal options plus rights on adjacent space. Plan 60–120 days from search to occupancy.

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