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    Winston Salem, NC

    Winston Salem, NC Commercial Real Estate for Lease

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    Winston-Salem, NC Kernersville, NC Walkertown, NC Rural Hall, NC Clemmons, NC High Point, NC Lewisville, NC Greensboro, NC
    8 properties
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    Two-Floor Flex Retail Gym Space
    Updated: Mar 23
    Two-Floor Flex Retail Gym Space

    610 N. Liberty Street, Winston Salem, NC 27101

    $12 SF/Yr
    8,374 sqft
    8,374 SF downtown Winston‑Salem building built in 1922
    Renovated in 2014 with a current two‑floor gym configuration
    Drive‑in door provides direct access for gym equipment and deliveries
    Men’s and women’s restrooms with dual showers (two showers each)
    Open, flexible interior layout adaptable for retail, fitness, or creative uses
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    Renovated Office and Lab Flex Buildings
    Updated: Jun 2
    Renovated Office and Lab Flex Buildings

    3041-3051 TRENWEST DRIVE WINSTON SALEM NC 27103, Winston Salem, NC 27103

    Contact for pricing
    6,430 sqft
    Two buildings with updated HVAC, plumbing, electrical, and roof (3041 Trenwest Dr and 3051 Trenwest Dr).
    3041 Trenwest Dr: 3,416 +/- SF professional office, renovated in 2025.
    3051 Trenwest Dr: 6,430 +/- SF lab/production with staff support, renovated in 2018.
    Prime location just off S Stratford Rd and within 2 miles of Novant Health Forsyth Med. Center (9,320 employees).
    Within 2 miles of Wake Forest Baptist Med. Center (14,000 employees).
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    Flex Office and Lab Buildings
    Flex Office and Lab Buildings

    3041-3051 Trenwest Dr, Winston Salem, NC 27103

    Contact for pricing
    9,846 sqft

    Two renovated flex buildings offer professional office space and lab/production with staff support uses.

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    Specialty Property For Lease
    Specialty Property For Lease

    1315 S Main St, Winston Salem, NC 27101

    $1,500/Mo

    Specialty property available for rent at 1315 S Main St, Winston-Salem, NC 27101.

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    Retail Space with Existing Shelving
    Retail Space with Existing Shelving

    528-520 N Martin Luther King Jr Dr, Winston Salem, NC 27101

    Contact for pricing

    Ready for immediate occupancy in a high-visibility corridor, with an established retail layout and existing shelving.

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    Commercial Land Near Home Depot
    Commercial Land Near Home Depot

    5713 University Pkwy, Winston Salem, NC 27105

    Contact for pricing

    Commercial land with access from multiple streets and a connection to a signalized intersection.

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    Industrial Space in Whitaker Park
    Industrial Space in Whitaker Park

    4015 Reynolds Ct, Winston Salem, NC

    Contact for pricing
    20,000 sqft 2.86 AC lot

    Industrial space for lease in North Winston, available Q3 2026.

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    Flex Industrial Space with Offices
    Flex Industrial Space with Offices

    6206 Hacker Bend Ct, Winston Salem, NC 27103

    Contact for pricing

    Single-level industrial-zoned space with reception, offices, open work/storage area, and two drive-in doors.

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    Based on your search, we've compiled 35 Potential Opportunities for your consideration. Besides 8 Active listings in Winston Salem, NC, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities, and Similar 23 Properties for Sales.

    Commercial real estate for Lease in Nearby Cities

    Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

    NC, Winston-Salem - W Third St
    NC, Winston-Salem - W Third St

    102 3Rd St, Winston-salem, NC 27101

    11 available spaces from 11 to 1,292 sqft
    $129-$4,498/Mo per office

    Flexible workspace in NC, Winston-Salem - W Third St. Book a tour & get info

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    Move-in Ready Medical Office Space
    Move-in Ready Medical Office Space

    725 Highland Oaks Dr, Winston-salem, NC

    Contact for pricing
    3,864 sqft 2.32 AC lot

    First floor medical office in convenient location near I-40.

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    Retail Space Near Medical Centers
    Retail Space Near Medical Centers

    55 Miller Street, Winston-salem, NC 27104

    Contact for pricing

    Retail space near hospitals and Whole Foods.

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    Suburban Office Space Available
    Suburban Office Space Available

    3410 Healy Dr, Winston-salem, NC

    Contact for pricing
    521 sqft 1.93 AC lot

    Office space for rent in convenient location near I-40.

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    Similar Spaces for Sale in Winston Salem, NC

    Consider Similar Space for Sale. We found 23 Spaces matching your search parameters.

    Mixed-Use Storefront with Upper Suites
    Mixed-Use Storefront with Upper Suites

    418-420 N. Liberty Street, Winston Salem, NC 27101

    $795,000
    8,150 sqft

    Two-level commercial property with display windows, street access, and renovated upper-floor suites.

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    Restaurant Property on Acreage
    Restaurant Property on Acreage

    3870 Bethania Station Rd, Winston Salem, NC 27106

    $975,000
    3,200 sqft 35.00 AC lot

    Two tax parcels comprise an approximately 35-acre offering, subject to survey and current zoning and restrictions.

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    Two-Story Flex Space with Bay Door
    Two-Story Flex Space with Bay Door

    610 N. Liberty Street, Winston Salem, NC 27101

    $1,250,000
    8,374 sqft

    Renovated two-level commercial space configured for gym operations with on-site parking and shower-equipped restrooms.

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    First-Floor Office Condominium
    First-Floor Office Condominium

    J-1-1365 Westgate Center Dr, Winston Salem, NC 27103

    $189,900
    1,000 sqft

    First-floor office suite with reception, open workspace, two private offices, and two bathrooms in a condo building.

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    Commercial Land with Subdivision Potential
    Commercial Land with Subdivision Potential

    3196 Peters Creek Parkway, Winston Salem, NC 27127

    $1,900,000
    2.80 AC lot

    Commercial parcel offering public sewer service and the ability to be divided into smaller sites.

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    NNN Retail Investment
    NNN Retail Investment

    920 HANES MALL BLVD, Winston Salem, NC 27103

    Contact for pricing
    6,000 sqft

    Single-tenant NNN retail property leased to Mattress Firm in Winston-Salem.

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    Retail Parcel Near US-52
    Retail Parcel Near US-52

    200 Fred Sink Road, Winston Salem, NC 27107

    $705,675
    2 sqft

    2.16 acre retail parcel off US-52 in Midway, NC.

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    Renovated Office/Retail Space with Parking
    Renovated Office/Retail Space with Parking

    361 W End Blvd, Winston Salem, NC 27101

    $450,000
    1,752 sqft 0.15 AC lot

    361 W End Blvd

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    1.49 Acre Commercial Land Parcel
    1.49 Acre Commercial Land Parcel

    2495 Hickory Tree Road, Winston Salem, NC 27127

    $139,500
    1 sqft

    1.49 acre commercial land with 279' frontage and 10,500 ADT.

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    Renovated Office Buildings Campus
    Renovated Office Buildings Campus

    3041-3051 Trenwest Dr, Winston Salem, NC 27103

    Contact for pricing
    9,846 sqft

    Two recently renovated office buildings with new HVAC, plumbing, electrical, and roof systems, offering professional and medical use options.

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    Retail Property in West End
    Retail Property in West End

    212 N Broad St, Winston Salem, NC 27101

    Contact for pricing
    13,493 sqft 0.49 AC lot

    Retail property in Winston-Salem's West End District for sale.

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    Industrial Land with Site Plans
    Industrial Land with Site Plans

    2601 Hope Church Rd, Winston Salem, NC 27103

    Contact for pricing
    4 sqft 4.10 AC lot

    Industrial-zoned land with engineered plans supporting evaluation of a future building project.

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    Historic Mixed-Use Building
    Historic Mixed-Use Building

    131 W. 4th Street, Winston Salem, NC 27101

    $1,950,000

    Street-level corner retail space is paired with unfinished upper-level areas for office or creative use.

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    Commercial Land with Subdivision Potential
    Commercial Land with Subdivision Potential

    3196 Peters Creek Parkway, Winston Salem, NC 27127

    $1,900,000

    Commercial land along Peters Creek Parkway with the ability to be divided into smaller parcels.

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    Commercial Land with Road Frontage
    Commercial Land with Road Frontage

    2288 Old Salisbury Rd, Winston Salem, NC 27127

    Contact for pricing
    0.76 AC lot

    The parcel sits across from Cagney’s Kitchen and beside DME Racing Motorcycle.

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    Commercial Land with Road Frontage
    Commercial Land with Road Frontage

    5455 University Pkwy, Winston Salem, NC 27105

    Contact for pricing

    New HB-C zoning provides flexibility for commercial development.

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    Winston Salem, NC Commercial real estate Market Trends and Statistics

    Explore Commercial real estate leasing options in Winston Salem, NC with 8 listings featured on our commercial real estate exchange. The current inventory includes 44,650 square feet of properties with an estimated lease value of $12.

    Estimated lease rates for Commercial real estate in Winston Salem, NC average $12 SF/Yr.
    Winston Salem, NC CRE market trends — vacancy, lease rates and price per SF, updated monthly
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    Most Searched ZIP Codes in Winston Salem, NC

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    • 27103
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