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San Mateo County, CA Flex Space for Lease

136 results
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San Mateo Commercial Warehouses
$12,900 / Mo
5,470 SF

San Mateo Commercial Warehouses

929-931 N Amphlett Blvd, San Mateo, CA 94401

Versatile warehouses ideal for logistics, office, or light industrial uses.

  • Prime visibility from Highway 101, offering significant brand exposure.
  • Strategic location with easy access to major freeways.
  • Versatile space suitable for logistics, office, or light industrial use.
  • Functional two‑story layout with multiple commercial roll‑up doors.
  • High ceilings and open work concept design.
Updated: Dec 18, 2025
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South San Francisco Warehouse Space
$21 SF/Yr
50,000 SF

South San Francisco Warehouse Space

274 Wattis Way, South San Francisco, CA 94080

Large warehouse, flexible lease options.

  • Five dock‑high doors.
  • Two ground‑level doors.
  • 16' clear ceiling height.
  • 16' high roll‑up doors.
  • Includes office space.
Updated: Dec 11, 2024
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ReadySpaces South San Francisco
$26 SF/Yr
60,000 SF

ReadySpaces South San Francisco

60,000 SF Industrial Space Available

233 Harris Ave, South San Francisco, CA 94080
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245 Spruce Ave
$25 SF/Yr
559,605 SF

245 Spruce Ave

Life science properties • 559,605 SF

245 Spruce Ave, South San Francisco, CA 94080
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Harrison Street Office/Flex Building
$27 SF/Yr
16,150 SF

Harrison Street Office/Flex Building

Two-story office/flex space with parking, high power, and amenities.

1177 Harrison St, San Francisco, CA 94103
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San Carlos Flex/Industrial Space
Contact for pricing
230,691 SF

San Carlos Flex/Industrial Space

Flex/industrial space in life science cluster, near Downtown San Carlos.

150 Industrial Rd, San Carlos, CA 94070
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Versatile Office/Medical/Flex Space Available
Contact for pricing
3,995 SF

Versatile Office/Medical/Flex Space Available

Adaptable 3,995 SF space suitable for office, medical, or flex use.

1750 Cesar Chavez St, San Francisco, CA 94107
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Modern Flex Facility in SoMA
$25 SF/Yr
8,000 SF

Modern Flex Facility in SoMA

15,500 SF flex suite in thriving San Francisco neighborhood.

361 Brannan St, San Francisco, CA 94107
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San Carlos Office/R&D Space
$45 SF/Yr
2,494 SF

San Carlos Office/R&D Space

Ground floor office/R&D space with expansion potential.

985 Industrial Rd, San Carlos, CA 94070
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San Francisco Flex/Industrial Space
$48 SF/Yr
10,000 SF

San Francisco Flex/Industrial Space

10,000 SF flex/industrial space available for lease.

1040 Mariposa St, San Francisco, CA 94107
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Flex/Industrial Space for Lease
$2 SF/Yr
6,915 SF

Flex/Industrial Space for Lease

Flex/industrial space available for lease, 6,915 square feet.

1251-1255 Howard St, San Francisco, CA 94103
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San Carlos Flex/Industrial Space
Contact for pricing
7,154 SF

San Carlos Flex/Industrial Space

Flex/Industrial space available for lease in San Carlos, CA.

1541-1549 Industrial Rd, San Carlos, CA 94070
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Redwood City Flex/Industrial Space
$6 SF/Yr
26,000 SF

Redwood City Flex/Industrial Space

Flex/Industrial space available for lease in Redwood City, CA.

501 Island Pkwy, Redwood City, CA 94065
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San Francisco Flex/Industrial Space
$24 SF/Yr
3,323 SF

San Francisco Flex/Industrial Space

Flex/Industrial space available for lease in San Francisco, CA.

590 10Th St, San Francisco, CA 94103
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San Mateo Flex / Industrial Space
Contact for pricing
6,559 SF

San Mateo Flex / Industrial Space

Flex / industrial space available for rent in San Mateo.

333-345 S B St, San Mateo, CA 94401
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San Francisco Flex/Industrial Space
$6,000,000
3,700 SF

San Francisco Flex/Industrial Space

3,700 SF flex/industrial space with highway visible signage.

189 13Th St, San Francisco, CA 94103
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Class A Office/Laboratory Space
Contact for pricing
15,617 SF

Class A Office/Laboratory Space

Office and laboratory space with amenities and shuttle service.

1900 Alameda De Las Pulgas, San Mateo, CA 94403
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Class A Flex Sublease
Contact for pricing
30,140 SF

Class A Flex Sublease

Flexible sublease with modern amenities and highway access.

333 Oyster Point Blvd, South San Francisco, CA 94080
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Furnished Flex Space in Mission
Contact for pricing
3,700 SF

Furnished Flex Space in Mission

3,700 SF flex space with mezzanine and flexible lease.

400-424 Treat Ave, San Francisco, CA 94110
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Redwood City Flex/Industrial/Office Space
$5 SF/Yr
15,121 SF

Redwood City Flex/Industrial/Office Space

15,121 SF flex, industrial, and office space for lease.

600-640 Galveston Dr, Redwood City, CA 94063
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San Mateo Creative/R&D Space
$1.99 SF/Yr
1,500 SF

San Mateo Creative/R&D Space

Newly remodeled 1,500 SF creative/R&D space for lease.

938 S Amphlett Blvd, San Mateo, CA 94402
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South San Francisco Flex Space
Contact for pricing
29,745 SF

South San Francisco Flex Space

Scalable flex space campus for life science companies.

450 E Jamie Ct, South San Francisco, CA 94080
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South San Francisco Flex Space
$1.15 SF/Yr
11,760 SF

South San Francisco Flex Space

11,760 SF flex space with office and warehouse areas.

300-332 Littlefield Ave, South San Francisco, CA 94080
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South San Francisco Lab Space
Contact for pricing
41,077 SF

South San Francisco Lab Space

Equipped lab space available for lease in South San Francisco.

951 Gateway Blvd, South San Francisco, CA 94080
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San Mateo County, CA Flex space Leasing Opportunities Market Analysis

Explore Flex space leasing options in San Mateo County, CA with 158 listings featured on our commercial real estate exchange. The current inventory includes 70,580,834,280 square feet of properties with an estimated lease value of $1,664 /Mo.

Estimated lease rates for Flex space in San Mateo County, CA begin at $0.99 SF/Yr, with an average of $21 SF/Yr and extend to $100 SF/Yr.
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