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    Wythe County, VA Commercial Real Estate for Sale

    92 results
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    Commercial Building in Wytheville, VA
    $150,000
    5,394 SF

    Commercial Building in Wytheville, VA

    610 W Lee Hwy, Wytheville, VA 24382

    5300 sq ft commercial building with long-term tenant.

    • 5300 sq ft commercial building offers substantial space.
    • Half of the building is currently rented to a long‑term auto repair tenant, providing immediate income.
    • Multi‑use space allows for flexible business operations.
    • Adequate parking available for customers and employees.
    • High visibility location attracts potential clients.
    Updated: Nov 13, 2025
    View details
    Downtown Wytheville Multi-Purpose Commercial Building
    $399,000
    4,949 SF

    Downtown Wytheville Multi-Purpose Commercial Building

    195 S 1St St, Wytheville, VA 24382

    Two-story commercial building with income potential in downtown Wytheville.

    • Prime downtown location on a busy corner.
    • Multi‑purpose, two‑story building with existing tenants.
    • Over 2,000 SF of available space on the second floor.
    • Well‑maintained building with a history of successful businesses.
    • Additional income potential from existing tenants.
    Updated: Nov 18, 2025
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    8.29 Acres with Income Potential
    $525,000
    8.29 Acres

    8.29 Acres with Income Potential

    Unique property with mobile homes, house, and income potential.

    134/190 Galilee Church Rd, Wytheville, VA 24382
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    Historic Office Space in Wytheville
    Contact for pricing

    Historic Office Space in Wytheville

    Furnished, move-in-ready office space in a recognizable historic building.

    150 W Main St, Wytheville, VA 24382
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    Mountain Home with Wooded Acreage
    $139,900
    1,568 SF

    Mountain Home with Wooded Acreage

    Secluded mountain home on 5.7 acres near Wytheville, Virginia.

    176 Dry Gulch Rd, Wytheville, VA 24382
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    Prime Wytheville Restaurant Opportunity
    $985,000
    6,064 SF

    Prime Wytheville Restaurant Opportunity

    6,064 SF Restaurant, $985,000

    190 Lithia Rd, Wytheville, VA 24382
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    Wytheville Commercial Building - High Visibility
    $179,000
    1.10 Acres

    Wytheville Commercial Building - High Visibility

    Prime Commercial Space, High Visibility, 5300 sq ft

    610 Lee Hwy, Wytheville, VA 24382
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    Prime Wytheville Car Wash Business
    $395,000
    2,400 SF

    Prime Wytheville Car Wash Business

    Profitable Car Wash - High Visibility

    425 Main St, Wytheville, VA 24382
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    Prime Wytheville Retail Investment
    $1,810,000
    4,400 SF

    Prime Wytheville Retail Investment

    High-cap rate, corporate-guaranteed Mattress Firm

    230 Commonwealth Dr, Wytheville, VA 24382
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    Fort Chiswell Mansion & Estate
    $3,900,000

    Fort Chiswell Mansion & Estate

    Versatile 38-acre estate with mansion, restaurant, and event venue.

    325 Factory Outlet Dr, Fort Chiswell, VA 24360
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    Fort Chiswell Mansion & Estate
    $2,900,000

    Fort Chiswell Mansion & Estate

    Versatile 5-acre estate with mansion, restaurant, and event venue.

    325B Factory Outlet Dr, Fort Chiswell, VA 24360
    View details

    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

    Industrial-Zoned Property in Wytheville, VA
    $299,000
    2.58 Acres

    Industrial-Zoned Property in Wytheville, VA

    2.58-acre industrial-zoned property near industrial park in Wytheville, VA.

    N 4Th St, Wytheville, VA 24382
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    Commercial Lot Near Interstate Exit
    $124,900
    39,630 SF

    Commercial Lot Near Interstate Exit

    Commercial land near I-81 exit with high traffic volume.

    Holston Rd, Wytheville, VA 24382
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    Commercial Lot Near Interstate Exit
    $124,900
    0.91 Acres

    Commercial Lot Near Interstate Exit

    Commercial lot near I-81 exit with high traffic volume.

    Holston Rd, Wytheville, VA 24382
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    Wytheville Land with B-2 Zoning
    $55,000
    0.70 Acres

    Wytheville Land with B-2 Zoning

    Vacant lot in Wytheville, VA, zoned B-2.

    lot 2A & 2A1 W Main St, Wytheville, VA 24382
    View details

    Explore Off-Market Properties in Wythe County, VA

    Consider similar Off-Market properties in Wythe County, VA. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

    610 North St

    610 North St

    Multifamily properties • 0.40 Acres
    Value Estimation by Request
    610 North St, Wytheville, VA 24382
    View details
    775 Franklin St

    775 Franklin St

    Multifamily properties • 0.50 Acres
    Value Estimation by Request
    775 Franklin St, Wytheville, VA 24382
    View details
    3553 Foster Falls Rd

    3553 Foster Falls Rd

    Individual retail properties • 8,320 SF
    Value Estimation by Request
    3553 Foster Falls Rd, Barren Springs, VA 24313
    View details
    800 Main St

    800 Main St

    Lifestyle centers • 99,745 SF
    Value Estimation by Request
    800 Main St, Wytheville, VA 24382
    View details
    800 Main St

    800 Main St

    Lifestyle centers • 99,854 SF
    Value Estimation by Request
    800 Main St, Wytheville, VA 24382
    View details
    205 Fairfield Ln

    205 Fairfield Ln

    Commercial real estate • 0.38 Acres
    Value Estimation by Request
    205 Fairfield Ln, Wytheville, VA 24382
    View details
    205 Fairfield Ln

    205 Fairfield Ln

    Multifamily properties • 4,696 SF
    Value Estimation by Request
    205 Fairfield Ln, Wytheville, VA 24382
    View details
    Tbd George James Dr

    Tbd George James Dr

    Commercial real estate • 29.93 Acres
    Value Estimation by Request
    Tbd George James Dr, Wytheville, VA 24382
    View details
    175 Tazewell St

    175 Tazewell St

    Commercial real estate • 0.13 Acres
    Value Estimation by Request
    175 Tazewell St, Wytheville, VA 24382
    View details
    3153 Chapman Rd

    3153 Chapman Rd

    Restaurants • 2,500 SF
    Value Estimation by Request
    3153 Chapman Rd, Wytheville, VA 24382
    View details
    142 George James Dr

    142 George James Dr

    Distribution properties • 42,750 SF
    Value Estimation by Request
    142 George James Dr, Wytheville, VA 24382
    View details
    1380 Main St

    1380 Main St

    Retail properties
    Value Estimation by Request
    1380 Main St, Wytheville, VA 24382
    View details
    198 Commonwealth Dr

    198 Commonwealth Dr

    Restaurants • 8,000 SF
    Value Estimation by Request
    198 Commonwealth Dr, Wytheville, VA 24382
    View details

    Wythe County, VA Commercial Real Estate Investment Opportunities Market Analysis

    Explore 627 commercial real estate investment opportunities in Wythe County, VA with 92 listings featured on our commercial real estate marketplace. The current inventory includes 290,865,715 square feet of properties with an estimated value of $259,701,300.

    Estimated prices for commercial real estate in Wythe County, VA begin at $32,500, with an average of $630,342 and extend to $8,695,000.

    In Wythe County, VA, current investment values show:

    • Other commercial real estate positioned at $707,808
    • Land measuring $291,536
    • Residential land & home lots assessed at $143,779
    • Commercial land calculated at $1,003,900
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    Commercial real estate by market

    Browse Commercial real estate for Sale Near Wythe, VA

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