Wytheville, VA Commercial Real Estate for Sale

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Two-Story Multi-Purpose Office Building
Updated: Feb 13
Two-Story Multi-Purpose Office Building

195 S 1st Street, Wytheville, VA 24382

$399,000
4,949 sqft
2‑story multi‑purpose building at 195 S 1st Street in downtown Wytheville
Over 2,000 SF of second‑floor space available, with current tenants occupying the main level
Block construction with rubber roof
Central HVAC with central air and heating via heat pump and natural gas
Public restrooms and exterior lighting
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Commercial Land Lot with High Visibility
Updated: May 27
Commercial Land Lot with High Visibility

1.36 AC N 4th St., Wytheville, VA 24382

$199,000
1.36 AC lot
1.36‑acre commercial lot in Wytheville, VA
B‑2 zoning
Great visibility with high elevation
Between O'Reilly's Auto Parts and Atlantic Union Bank on Wytheville's busiest street
Within sight of I‑81
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Expansive Land Parcel in Wytheville
Expansive Land Parcel in Wytheville

Community Blvd lot: 131, Wytheville, VA 24382

$2,950,000
87.66 AC lot

87+ acre parcel ideal for commercial or residential development.

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Grocery-Anchored Shopping Center
Grocery-Anchored Shopping Center

1380 E Main St, Wytheville, VA 24382

$8,060,550
87,964 sqft 9.20 AC lot

Grocery-anchored shopping center offering 87,964 square feet on 9.196 acres at the I-81/I-77 intersection.

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B2 Zoned Commercial Land
B2 Zoned Commercial Land

1160 W Lee Highway, Wytheville, VA 24382

$169,000
12.50 AC lot

B2-zoned commercial land with water available, mature trees, and an older structure for potential rehab.

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Industrial-Zoned Property in Wytheville, VA
Industrial-Zoned Property in Wytheville, VA

N 4th Street, Wytheville, VA 24382

$299,000
2.58 AC lot

2.58-acre industrial-zoned property near industrial park in Wytheville, VA.

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Wytheville Land with B-2 Zoning
Wytheville Land with B-2 Zoning

W Main Street lot: 2A & 2A1, Wytheville, VA 24382

$55,000
0.70 AC lot

Vacant lot in Wytheville, VA, zoned B-2.

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Owner-Occupant Office with Parking
Owner-Occupant Office with Parking

170 S 16th St, Wytheville, VA 24382

$170,000
1,080 sqft

Office property in Wytheville with its own parking lot and storage building, suited for owner-occupants or investors.

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Industrial Land Development Site
Industrial Land Development Site

Stafford Umberger Drive, Wytheville, VA 24382

$2,600,000
35.00 AC lot

Nearly level industrial land with road frontage on Stafford Umberger Drive, US Hwy 52/N 4th St, and Fairview Road.

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Grocery-Anchored Retail Center
Grocery-Anchored Retail Center

1370-1380 E Main St, Wytheville, VA 24382

Contact for pricing
87,964 sqft

100% occupied grocery-anchored center with contractual rent growth and national credit tenants across grocery, pharmacy, and lifestyle retail.

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Retail Property at Interstate Convergence
Retail Property at Interstate Convergence

145 Commonwealth Drive, Wytheville, VA 24382

Contact for pricing
4,696 sqft

Retail building positioned at the I-77 and I-81 convergence with visibility to more than 30,000 vehicles daily.

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Car Wash with Automatic and Self-Serve Bays
Car Wash with Automatic and Self-Serve Bays

425 E Main St, Wytheville, VA 24382

$280,000
2,400 sqft

Car wash offering one automatic bay and two self-serve bays, plus a dog wash amenity.

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Chipotle Drive-Through Restaurant
Chipotle Drive-Through Restaurant

1245 Tazewell Street, Wytheville, VA 24382

Contact for pricing
2,325 sqft

Corporate-leased quick-service restaurant near US Route 21 and the I-81/I-77 interchange.

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Mixed-Use Building with Open Layout
Mixed-Use Building with Open Layout

1340 W Main St, Wytheville, VA 24382

Contact for pricing
14,519 sqft

Mixed-use building offering office and storefront space with an open floor plan and potential upstairs apartment conversion.

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Mattress Firm Retail Investment Opportunity
Mattress Firm Retail Investment Opportunity

230 Commonwealth Dr, Wytheville, VA 24382

Contact for pricing
4,400 sqft

Freestanding Mattress Firm at I-81 & I-77 crossroads.

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Historic Mixed-Use Main Street Property
Historic Mixed-Use Main Street Property

515 E Main St, Wytheville, VA 24382

Contact for pricing
2,340 sqft

Mixed-use building with a former grocery storefront on the lower level and an apartment above, offering flexible restoration options.

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Retail Space on 1.26 Acres
Retail Space on 1.26 Acres

190 Lithia Rd, Wytheville, VA 24382

Contact for pricing
6,064 sqft 1.26 AC lot

6,064 SF retail space in I-81/I-77 Crossroads development.

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Commercial Land with Long-Range Views
Commercial Land with Long-Range Views

1160 W Lee Highway, Wytheville, VA 24382

Contact for pricing

B2-zoned acreage includes mature trees and an existing older structure with possible rehabilitation potential.

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Interstate-Fronting Development Land
Interstate-Fronting Development Land

2220 E Lee Highway, Wytheville, VA 24382

Contact for pricing

8.838-acre parcel on the I-81/I-77 concurrency with convenient access for logistics, truck services, and travel-oriented development.

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Net Leased Captain D's Restaurant
Net Leased Captain D's Restaurant

215 E. Commonwealth Dr., Wytheville, VA 24382

Contact for pricing

Single-tenant Captain D’s restaurant offered with an absolute net long-term lease structure requiring zero landlord responsibilities.

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Corner 8-Room Office Building
Corner 8-Room Office Building

105 W Pine St, Wytheville, VA 24382

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An 8-room office building on a corner with reception area and multiple office and bathroom spaces across two levels.

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Based on your search, we've compiled Potential Opportunities for your consideration. Besides 21 Active Listings in Wytheville, VA, we suggest to view alternatives - similar 51 Off-Market properties to explore as potential leads.

Off-Market Properties in Wytheville, VA

Consider similar Off-Market properties in Wytheville, VA. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

610 Lee Hwy
COMMERCIAL (GENERAL)

610 Lee Hwy, Wytheville, VA 24382-1708

Value Estimation by Request
5,394 sqft 0.99 AC lot
View details
225 Sandrel Ln
COMMERCIAL (GENERAL)

225 Sandrel Ln, Wytheville, VA 24382-9605

Value Estimation by Request
2,032 sqft 1.25 AC lot
View details
110 Spiller St
COMMERCIAL (GENERAL)

110 Spiller St, Wytheville, VA 24382-1952

Value Estimation by Request
4,500 sqft 1.10 AC lot
View details

Wytheville, VA Commercial Real Estate Market Trends and Statistics

Explore 72 commercial real estate for sale in Wytheville, VA, showcased through 21 active listings on our real estate platform. These investment opportunities span a total of 218,701 square feet of properties for sale, with an estimated market value of $15,181,550.

Sale prices for business properties in Wytheville, VA start at $55,000, averaging $1,518,155, and reaching up to $8,060,550 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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Demographics Overview

Population 15K
Population Growth (5Y) +9.9%
Median Household Income $52,234
College Educated 33.1%

High-Yield Neighborhoods for Investment

Identify Wytheville submarkets with the highest inventory density on the market and evaluate the average listing prices of real estate assets

Neighborhood Average Price
24382 $1.5M

Taxes & Financing

Tax Rate (average for all types) 2.50%
Property Tax per SF $47.10 per SF
Average Loan-to-Value 65.0%

Listings Trend

New vs delisted commercial listings in Wythe County

New Delisted

Total CRE Inventory on Market (SF)

Average Property Price per SF

For-sale pricing trends across core commercial property types in Wythe County

Retail

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