Commercial Real Estate Market in Santee, SC
Updated monthly: sale, lease, property records, location trend, and more… · Last update: August 31
31 active listings and 250 off-market properties in Santee, SC.
Market Trends
Santee, SC spans 50.9 square miles in Orangeburg County, South Carolina. Figures below refresh monthly; last updated 31 August 2026.
Office
Office vacancy in Santee, SC runs 20.2% across the South region in 2025, up from 14.4% in 2019.
Retail
Retail vacancy in Santee, SC runs 5.4% across the South region in 2025, down from 7% in 2020.
Industrial
Industrial vacancy in Santee, SC runs 7.9% across the South region in 2025, up from 6% in 2019. Nearly 2.3x the 2022 low of 3.5%.
Multifamily
Multifamily vacancy in Santee, SC runs 11.3% across the South region in 2025, up from 8.5% in 2022.
Zoning & Land Use
Land Use Mix share of zoned land by category
- Residential 58.6%
- Commercial 35.7%
- Planned_development 3.6%
- Industrial 2.1%
Largest Zones share of zoned land by district
Santee, SC zones 1,351 acres across 8 districts. Commercial zoning covers 35.7% of zoned land, residential 58.6% and industrial 2.1%. The largest single district is General Commercial District at 29%. For commercial buyers the practical constraint is that only 37.8% of land carries a commercial or industrial designation.
The purpose of the GC District is to provide for areas within the town where a variety of commercial developments and residential uses may take place
Market overview
Demographics & Economy
Santee, SC has 4,432 residents in 2,083 households. Density runs 87 people per square mile. Median household income here is $50,673 and median gross rent $944 a month.
Tools
Nearby Markets
| Market | Average Sale Price, $/SF | Average Lease Price, $/SF/Yr |
|---|---|---|
| Parlers | — | — |
| Vance | — | — |
| Felderville | — | — |
| Elloree | — | — |
Commercial property in Santee, SC asks $22/SF.
Frequently Asked Questions
What is the average price per square foot for commercial property in Santee?
What zoning applies to commercial property in Santee?
Where does Realmo's Santee market data come from?
Methodology & data sources
- Asking prices and averages
- Computed from 31 active for-sale and 0 active for-lease listings in Santee, SC. These are ASKING figures from live listings, not closed-transaction prices, and a segment carried by a handful of listings reads as indicative rather than an average.
- Vacancy rates
- Published per-sector market series, taken at the metro level where one exists and otherwise at the Census-region level — a chart reading "in <region> region" is a regional number, not this city's.
- Zoning and land use
- The current municipal zoning release: 1,351 zoned acres across 8 districts. Shares are of zoned land, so parcels the release leaves unclassified are excluded from the mix.
- Refresh
- The monthly aggregates close at the end of the previous month, so 31 August 2026 — not today — is the honest last update.
- Known limitations
- office vacancy is reported at South region level, retail vacancy is reported at South region level and industrial vacancy is reported at South region level.
- Coverage
- Metrics below the 10-observation threshold fall back one geographic level. The geography used is named on each figure.
Compiled by the Realmo Data team · reviewed 31 August 2026 · report a data issue