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Santee, SC Commercial Real Estate for Sale

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Highway Commercial Property with Storage
$1,900,000
3,282 SF

Highway Commercial Property with Storage

9158 Old Number Six Hwy, Santee, SC 29142

Commercial building with storage units near I-95 in Santee.

  • High visibility location near Highway 6 and I‑95.
  • Commercial property designed for two separate businesses.
  • 22 storage units at the rear of the property currently rented.
  • Second story suitable for offices or storage.
  • Located near Somerset homes and across from Santee‑Cooper Resort entrance.
Updated: Nov 13, 2025
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Lakefront Condo with Balcony
$225,500
1,251 SF

Lakefront Condo with Balcony

161 Ballard Ln, Santee, SC 29142

Two-bedroom, two-bathroom condo with lake views and balcony.

  • Stunning lakefront views of Lake Marion.
  • Direct access to Lake Marion's boating, fishing, and recreational activities.
  • Private balcony perfect for relaxation and enjoying lake views.
  • Updated kitchen and open floor plan with spacious living and dining areas.
  • Convenient location just off I95, 1 hour drive to Charleston and Columbia.
Updated: Jan 20, 2025
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Freestanding Retail Property For Sale
$1,394,000
9,993 SF

Freestanding Retail Property For Sale

Freestanding retail property with investment-grade tenant Dollar Tree.

100 Bass Dr, Santee, SC 29142
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Based on your search, we've compiled 261 Potential Opportunities for your consideration. Besides 3 Active listings in Santee, SC, we suggest exploring several alternatives: 4 properties in Nearby Cities, and similar 250 Off-Market properties to explore as potential leads, plus 4 Land Listings that present a potential for development.

Explore Opportunities in Nearby Cities

Here are 4 Similar properties we found in Nearby Locations for your consideration.

Residential Land Near Santee State
Contact for pricing
0.69 Acres

Residential Land Near Santee State

Partially cleared 0.69 acre lot near Santee State Park.

Sorin Cir, Elloree, SC 29047
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Entitled RV Park Land
$900,000
10.97 Acres

Entitled RV Park Land

10+ acre entitled RV park near lakes and Santee State Park.

Tee Vee Rd, Elloree, SC 29047
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Cottage-Style Duplex Near Lake Marion
$290,000
1,664 SF

Cottage-Style Duplex Near Lake Marion

Charming duplex with income potential near Lake Marion.

1201 Crescent St, Summerton, SC 29148
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Lakefront Land on Lake Marion
$699,000
2.20 Acres

Lakefront Land on Lake Marion

2.2 acres with 487 feet of pristine waterfront.

3226 Francis Marion Blvd, Summerton, SC 29148
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Potential Development Sites for Consideration

Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

Commercial Land Near I-95
$705,000

Commercial Land Near I-95

Shovel-ready commercial land in high-traffic area near I-95.

301 Bass Drive/Hwy, Santee, SC
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Prime Commercial Land Near I-95
$339,000

Prime Commercial Land Near I-95

Shovel-ready land near I-95, ideal for retail development.

676 Bass Dr, Santee, SC 29142
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Santee Commercial Land Near I-95
$339,000
4 SF

Santee Commercial Land Near I-95

4.65 acres of commercial land near I-95 in Santee, SC.

656 Bass Dr, Santee, SC 29142
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Corner Lot with High Visibility
$1,416,000
16.66 Acres

Corner Lot with High Visibility

Located at I-95 Exit 97, highly visible corner lot.

15 And 301, Santee, SC 29142
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Explore Off-Market Properties in Santee, SC

Consider similar Off-Market properties in Santee, SC. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

123 Mall St

123 Mall St

Hotels • 52,000 SF
Value Estimation by Request
123 Mall St, Santee, SC 29142
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Empire Ln

Empire Ln

Residential income homes
Value Estimation by Request
0 Empire Ln, Santee, SC 29142
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514 Bass Dr

514 Bass Dr

Specialty properties
Value Estimation by Request
514 Bass Dr, Santee, SC 29142
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6 Off Hwy

6 Off Hwy

MINI-WAREHOUSE, STORAGE • 0.77 Acres
Value Estimation
$130,000
6 Off Hwy, Santee, SC 29142
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Hwy 30115

Hwy 30115

MINI-WAREHOUSE, STORAGE • 1,250 SF
Value Estimation by Request
Hwy 30115, Santee, SC 29142
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204 John Lawson Ave

204 John Lawson Ave

DISTRIBUTION WAREHOUSE • 55,297 SF
Value Estimation
$575,000
204 John Lawson Ave, Santee, SC 29142
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Int Hwy 301

Int Hwy 301

LUMBERYARD, BUILDING MATERIALS • 4.00 Acres
Value Estimation
$120,000
Int Hwy 301, Santee, SC 29142
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Hwy 6th 6

Hwy 6th 6

MINI-WAREHOUSE, STORAGE • 5,376 SF
Value Estimation
$215,000
Hwy 6th 6, Santee, SC 29142
View details
1915 Bass Dr

1915 Bass Dr

MINI-WAREHOUSE, STORAGE • 2,400 SF
Value Estimation by Request
1915 Bass Dr, Santee, SC 29142-8987
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758 Bass Dr

758 Bass Dr

DISTRIBUTION WAREHOUSE • 9,000 SF
Value Estimation
$150,000
758 Bass Dr, Santee, SC 29142-8941
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736 Bass Dr

736 Bass Dr

MINI-WAREHOUSE, STORAGE • 2,005 SF
Value Estimation
$150,000
736 Bass Dr, Santee, SC 29142-8941
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9158 Hwy 6th 6

9158 Hwy 6th 6

MINI-WAREHOUSE, STORAGE • 2,592 SF
Value Estimation
$180,000
9158 Hwy 6th 6, Santee, SC 29142
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9183 Old Number 6th Hwy

9183 Old Number 6th Hwy

MANUFACTURING (LIGHT) • 6,300 SF
Value Estimation
$120,000
9183 Old Number 6th Hwy, Santee, SC 29142-8899
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5 Chop Rd

5 Chop Rd

MANUFACTURING (LIGHT) • 3.90 Acres
Value Estimation
$215,000
5 Chop Rd, Santee, SC 29142
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5 Chop Rd

5 Chop Rd

MANUFACTURING (LIGHT) • 8.30 Acres
Value Estimation
$195,000
5 Chop Rd, Santee, SC 29142
View details
8921 Old Number 6th Hwy

8921 Old Number 6th Hwy

DRIVE-THRU RESTAURANT, FAST FOOD • 2,808 SF
Value Estimation
$195,000
8921 Old Number 6th Hwy, Santee, SC 29142
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Hwy 6th 6

Hwy 6th 6

RETAIL STORES (PERSONAL SERVICES) • 5,820 SF
Value Estimation
$185,000
Hwy 6th 6, Santee, SC 29142
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8909 Old Number 6th Hwy

8909 Old Number 6th Hwy

CONVENIENCE STORE • 5,880 SF
Value Estimation
$245,000
8909 Old Number 6th Hwy, Santee, SC 29142-8606
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Hwy 6th 6

Hwy 6th 6

CONVENIENCE STORE • 7,587 SF
Value Estimation
$220,000
Hwy 6th 6, Santee, SC 29142
View details
8949 Old Number 6th Hwy

8949 Old Number 6th Hwy

CONVENIENCE STORE • 1,248 SF
Value Estimation
$140,000
8949 Old Number 6th Hwy, Santee, SC 29142-8606
View details
Hwy 6th 6

Hwy 6th 6

COUNTRY CLUB • 9.00 Acres
Value Estimation
$180,000
Hwy 6th 6, Santee, SC 29142
View details

Santee, SC Commercial Real Estate Investment Opportunities Market Analysis

Explore 194 commercial real estate investment opportunities in Santee, SC on our commercial real estate marketplace. The current inventory includes 11,739,289 square feet of properties with an estimated value of $37,348,100.

Estimated prices for commercial real estate in Santee, SC begin at $50,000, with an average of $718,232 and extend to $8,770,000.

In Santee, SC, current investment values show:

  • Retail properties positioned at $577,045
  • Land measuring $552,364
  • Restaurants assessed at $505,000
  • Individual retail properties calculated at $629,375
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