Lancaster, OH Commercial Real Estate for Sale

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Remodeled Medical Office Building
Updated: Apr 3
Remodeled Medical Office Building

435 E Main Street, Lancaster, OH 43130

$475,000
3,445 sqft 0.13 AC lot
Seller financing available
Income‑generating 2‑bedroom apartment currently rented for $750/month
Remodeled interior in 2016
Former medical office layout featuring 5 offices/exam rooms, lab, and conference room
ADA accessibility
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This listing looks promising.

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435 E Main Street, Lancaster, OH 43130

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High Profile Corner Retail Property
Updated: Oct 1, 2025
High Profile Corner Retail Property

1301 E Main Street, Lancaster, OH 43130

$350,000
1,260 sqft 0.30 AC lot
High‑profile corner location on Lancaster's eastside business corridor.
General Commercial zoning permits diverse uses like retail, restaurant, or office.
Easy access via driveways on both East Main Street and Ewing Street.
Adjacent to medical offices and Fairfield Medical Center.
Utilities available: Water and Public Sewer.
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Oil Change Service Center NNN
Oil Change Service Center NNN

2473 North Memorial Drive, Lancaster, OH 43130

$1,666,667
1,683 sqft 0.45 AC lot

Freestanding Take 5 Oil Change property with a new 20-year NNN lease commencing at close of escrow.

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Flex Industrial Property with Office
Flex Industrial Property with Office

432 South Ewing Street, Lancaster, OH 43130

$975,000
1,344 sqft 5.75 AC lot

Multi-building industrial site with office space, drive-through doors, and loading docks across four pole buildings.

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Agricultural Land with Mixed Tillable Ground
Agricultural Land with Mixed Tillable Ground

2145 W Point Road, Lancaster, OH 43130

$649,900
35.00 AC lot

35-acre property with tillable land, woods, pasture, and alfalfa for farming, expansion, or a rural homesite.

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Lancaster Medical Office Investment Opportunity
Lancaster Medical Office Investment Opportunity

1781 Countryside Dr, Lancaster, OH

$2,650,000
9,954 sqft 1.80 AC lot

Single-tenant medical office building leased through 2032.

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Lancaster Mixed-Use Investment Opportunity
Lancaster Mixed-Use Investment Opportunity

530-532 N Columbus Street, Lancaster, OH 43130

$575,000
4,960 sqft

Turnkey mixed-use building with bar and renovated apartments.

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Flat Industrial Land with Rail Exposure
Flat Industrial Land with Rail Exposure

Quarry Road SE, Lancaster, OH 43130

$690,000
8.63 AC lot

8.6+ acres of flat industrial land with 850+ feet of Quarry Road frontage and rail exposure along the southern line.

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Lancaster Commercial Land For Sale
Lancaster Commercial Land For Sale

Slocum Avenue, Lancaster, OH 43130

$230,000
3.15 AC lot

3+ acres of commercial land near a commercial corridor.

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Lancaster Retail Property For Sale
Lancaster Retail Property For Sale

1133-1141 N Memorial Dr, Lancaster, OH

$1,100,000
13,482 sqft 0.11 AC lot

Retail property available for purchase in Lancaster, Ohio.

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Industrial Land on East Main
Industrial Land on East Main

E Main Street, Lancaster, OH 43130

$1,575,000
26.24 AC lot

26+ acres of industrial land with rail exposure.

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Office Building Near Downtown Lancaster
Office Building Near Downtown Lancaster

1941 E Main St, Lancaster, OH

$500,000
3,914 sqft 0.93 AC lot

3,914 SF office building with ample parking and signage.

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Mixed-Use Farm Land Tract
Mixed-Use Farm Land Tract

2145 West Point Road, Lancaster, OH 43130

$649,900

A mixed farmland tract with tillable acres, woods, pasture, and alfalfa for flexible rural ownership.

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Retail Space in High Profile Corridor
Retail Space in High Profile Corridor

1541 River Valley Blvd, Lancaster, OH 43130

$3,522,600
23,484 sqft

Retail space with strong tenancy in a high-profile location.

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Healthcare Property with Ample Parking
Healthcare Property with Ample Parking

1973 East Main Street, Lancaster, OH 43130

$400,000
3,914 sqft

Healthcare property near downtown Lancaster with monument signage and parking.

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Corner Commercial Lot in DORA
Corner Commercial Lot in DORA

301 S Broad Street, Lancaster, OH 43130

$50,000
0.05 AC lot

Corner commercial lot in Lancaster within the DORA district, with utilities available at the road.

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Vacant Land in Northwest Lancaster
Vacant Land in Northwest Lancaster

1631 Hubbard Drive, Lancaster, OH 43130

$139,900
0.99 AC lot

Just under an acre of vacant land with utilities available.

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Lancaster Industrial Land for Sale
Lancaster Industrial Land for Sale

0 Quarry Rd Se, Lancaster, OH 43130

$690,000
8.63 AC lot

8.6 acres of industrial land with rail exposure.

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Versatile Office Building in Lancaster
Versatile Office Building in Lancaster

830 E. Main St., Lancaster, OH 43130

$399,900
1,904 sqft

Adaptable office building in high-traffic location, suitable for various uses.

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Renovated Commercial Building in Lancaster
Renovated Commercial Building in Lancaster

117 E 6th Avenue, Lancaster, OH 43130

$219,900
1,432 sqft

Fully renovated commercial building in high-traffic Lancaster location.

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Land with Basement Walk-Out Potential
Land with Basement Walk-Out Potential

Highland Avenue, Lancaster, OH 43130

$34,900
0.48 AC lot

0.48 acre lot with utilities available in Lancaster, Ohio.

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Vacant Lot in Lancaster, OH
Vacant Lot in Lancaster, OH

157 Cedar Hill Road, Lancaster, OH 43130

Contact for pricing
0.13 AC lot

Vacant 5,719 SF lot with utilities in Lancaster, OH.

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Storefront Property for Sale
Storefront Property for Sale

146 E WINDING ST, Lancaster, OH 43130

Contact for pricing
3,771 sqft

Court-ordered auction sale with strict access limits and an as-is, where-is purchase process.

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Pad Ready Site Near Lowe's
Pad Ready Site Near Lowe's

0 N Columbus St, Lancaster, OH

$550,000
1.25 AC lot

1.25 acre commercial land adjacent to retail and medical.

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Lancaster, OH Commercial Real Estate Market Trends and Statistics

Explore 72 commercial real estate for sale in Lancaster, OH, showcased through 27 active listings on our real estate platform. These investment opportunities span a total of 70,776 square feet of properties for sale, with an estimated market value of $12,834,067.

Sale prices for business properties in Lancaster, OH start at $219,900, averaging $1,069,505, and reaching up to $3,522,600 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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Demographics Overview

Population 62K
Population Growth (5Y) +1.9%
Median Household Income $68,242
College Educated 30.6%

High-Yield Neighborhoods for Investment

Identify Lancaster submarkets with the highest inventory density on the market and evaluate the average listing prices of real estate assets

Neighborhood Average Price
43130 $844.8K

Taxes & Financing

Average Loan-to-Value 65.0%

Listings Trend

New vs delisted commercial listings in Fairfield County

New Delisted

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