St Charles County, MO Commercial Real Estate for Sale

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Saint Charles Office/Flex Building
Saint Charles Office/Flex Building

500 Fountain Lakes Blvd, Saint Charles, MO 63301

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53,932 sqft

Class A office/flex building in a prime Saint Charles location.

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Flex Space Building with Drive-In Doors
Flex Space Building with Drive-In Doors

4524 S Saint Peters Parkway, St Peters, MO 63304

$1,600,000
0.91 AC lot

Flex space building zoned C-3 with climate-controlled office/showroom and warehouse areas plus ADA access and drive-in doors.

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Commercial Land with Highway Frontage
Commercial Land with Highway Frontage

O Fallon, MO 63366

$223,240
1.28 AC lot

Zoned C-2 and positioned for visibility near I-70 access off Veterans Memorial Parkway in O’Fallon.

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O'Fallon Leased Office Investment
O'Fallon Leased Office Investment

O Fallon, MO 63366

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5,208 sqft 0.62 AC lot

Leased office building in O'Fallon, Missouri, with stable income.

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Office Building with Power Backup
Office Building with Power Backup

2070 Little Hills Expy, Saint Charles, MO 63301

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41,125 sqft 4.75 AC lot

Office building offering a drive-in door, UPS and generator support, and extensive on-site parking.

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Modern Office Space Available
Modern Office Space Available

11400 Veterans Memorial Pkwy, Lake Saint Louis, MO 63367

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8,012 sqft

Modern office space with flexible layouts and state-of-the-art amenities.

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Retail Suite with 5,600 SF
Retail Suite with 5,600 SF

St Peters, MO 63376

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5,600 sqft

Retail suite available for sale, totaling 5,600 SF.

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Restaurant, Bar & Patio on Main
Restaurant, Bar & Patio on Main

515 South main Street, Saint Charles, MO 63301

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1,900 sqft

Fully operational restaurant, bar, and patio on Historic Main Street.

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Commercial Development Land Parcel
Commercial Development Land Parcel

6219 S Highway 94, Weldon Spring, MO 63304

$579,348
1.90 AC lot

1.9-acre parcel with utilities and strong highway frontage, positioned for future commercial zoning consideration.

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Freestanding Retail Building with Monument Signage
Freestanding Retail Building with Monument Signage

O Fallon, MO 63366

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11,058 sqft 1.44 AC lot

Freestanding retail building zoned C-2 in the Downtown Overlay District with 71 parking spaces and a new roof (Oct. 2025).

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Vacant Car Wash with Equipment
Vacant Car Wash with Equipment

1525 Jungermann Road, St Peters, MO 63376

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4,219 sqft

Existing equipment accompanies this vacant automotive facility.

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Jack in the Box QSR Building
Jack in the Box QSR Building

3710 Elm St, Saint Charles, MO 63301

$1,512,000

Quick-service restaurant property operated by Jack in the Box since the building was constructed in 1999.

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Move-In-Ready Flex Industrial Building
Move-In-Ready Flex Industrial Building

140 N Point Prairie Rd, Wentzville, MO 63385

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18,000 sqft 4.78 AC lot

Move-in-ready flex/industrial building with pre-engineered steel construction, parking for 95 cars, and 380 feet of frontage.

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Industrial Warehouse with Outside Storage
Industrial Warehouse with Outside Storage

3080 Elm Point Industrial Dr, Saint Charles, MO 63301

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30,240 sqft 3.04 AC lot

Warehouse offers 18’ clear heights, dock-high and grade-level doors, and fenced outside storage on 3+ acres.

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Historic Tavern and Restaurant
Historic Tavern and Restaurant

Saint Charles, MO 63301

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1,900 sqft

Income-producing hospitality operation offered for sale within a historically significant main-street structure with private showings by appointment.

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Corner Commercial Land
Corner Commercial Land

6312 Weldon Springs Road, Weldon Spring, MO 63304

$262,234
0.86 AC lot

Commercially zoned corner parcel with public water and sewer available.

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Leased Multi-Tenant Office Building
Leased Multi-Tenant Office Building

St Peters, MO 63376

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4,000 sqft

Multi-tenant office building is 100% leased and offered with a reported 7.5% cap rate.

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Free-Standing Medical Office Building
Free-Standing Medical Office Building

11 Garvey Pkwy, Saint Charles, MO 63303

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6,676 sqft

Free-standing brick medical office building built in 2005 with 32 parking spaces and 100% occupied long-term medical lease.

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C-1 Commercial Land
C-1 Commercial Land

O Fallon, MO 63366

$219,900
0.76 AC lot

C-1-zoned parcel with on-site utilities near established professional office buildings.

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Gated Flex Space with Outdoor Storage
Gated Flex Space with Outdoor Storage

Saint Charles, MO 63301

$650,000
1.33 AC lot

Flexible office, warehouse, and shop configuration with secured outdoor areas and direct access for industrial operations.

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Furnished Bar and Restaurant Building
Furnished Bar and Restaurant Building

1565 River View St, Portage Des Sioux, MO 63373

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3,600 sqft 1.00 AC lot

Turnkey furnished bar and restaurant with hood, coolers, and walk-in storage on 1 acre.

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Multi-Tenant Industrial Property For Sale
Multi-Tenant Industrial Property For Sale

O Fallon, MO 63366

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31,568 sqft 2.32 AC lot

31,568 SF industrial property with 100% occupancy and highway frontage.

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Retail Center on Highway 94
Retail Center on Highway 94

1030-1120 Wolfrum, Weldon Spring, MO 63304

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51,474 sqft

Retail center with high visibility and easy highway access.

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Farm Property with Creek
Farm Property with Creek

2701 Freymuth Rd, O Fallon, MO

$4,224,000
2,576 sqft

Large agricultural tract with two road access points, available utilities, a central creek, and an existing residence conveyed as-is.

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