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    Perryville, MO Commercial Real Estate for Sale

    10 results
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    Historic Brick Office Building
    $215,000
    1,980 SF

    Historic Brick Office Building

    17 E Saint Joseph St, Perryville, MO 63775

    Turn-key office building in flourishing downtown Perryville.

    • Turn‑key, income‑generating property with five separate office rentals.
    • Shared meeting room/workspace provides potential for additional revenue.
    • Located in a flourishing downtown area.
    • Includes some equipment, furniture, and business amenities.
    • Charming curb appeal with professional landscaping and signage.
    Updated: Sep 15, 2025
    View details
    Mixed-Use Property in Downtown Perryville
    $3,030,000
    20,600 SF

    Mixed-Use Property in Downtown Perryville

    104-110 N Jackson St, Perryville, MO 63775

    Multi-tenant property with residential and commercial units in downtown Perryville.

    • Prime downtown location on the square in Perryville.
    • Diversified income streams from eight residential units and four fully leased commercial units.
    • Substantial size: over 20,000 square feet.
    • Major structural improvements to commercial units, including electrical and HVAC systems.
    • Established cash flow and long‑term upside potential.
    Updated: Dec 17, 2025
    View details
    Downtown Perryville Commercial Building
    $325,000
    0.23 Acres

    Downtown Perryville Commercial Building

    Mixed-use commercial building with income potential in downtown Perryville, MO.

    19 S Jackson St, Perryville, MO 63775
    View details
    Turnkey Day Care Facility
    $131,000
    0.23 Acres

    Turnkey Day Care Facility

    Ready-to-go day care with playground and equipment included.

    500 W North St, Perryville, MO 63775
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    Downtown Perryville Commercial Property
    $550,000
    0.72 Acres

    Downtown Perryville Commercial Property

    Established commercial property with tenant in place in downtown Perryville.

    304 W South St, Perryville, MO 63775
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    Turnkey Perryville Hospitality Property
    $560,000
    3,143 SF

    Turnkey Perryville Hospitality Property

    Fully operational venue suitable for Airbnb, B&B, or events.

    221 W Saint Joseph St, Perryville, MO 63775
    View details
    221 Saint Joseph St, Perryville, MO 63775
    $474,900
    0.36 Acres

    221 Saint Joseph St, Perryville, MO 63775

    Commercial real estate • 0.36 Acres

    221 Saint Joseph St, Perryville, MO 63775
    View details
    Prime Perryville Commercial Land
    $649,900
    17.38 Acres

    Prime Perryville Commercial Land

    17 Acres, Highway 55 Visibility

    1100 Cinque Hommes Dr, Perryville, MO 63775
    View details
    Perryville Commercial Land Development
    $611,500
    5.61 Acres

    Perryville Commercial Land Development

    Prime 5.61-acre commercial lot, 15 buildable lots.

    Redbud Ct, Perryville, MO 63775
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    New Starbucks with Drive-Thru
    $2,803,000
    2,443 SF

    New Starbucks with Drive-Thru

    New construction Starbucks with drive-thru and outdoor patio.

    1111 S Perryville Blvd, Perryville, MO 63775
    View details
    Based on your search, we've compiled 611 Potential Opportunities for your consideration. Besides 10 Active listings in Perryville, MO, we suggest exploring several alternatives: 4 properties in Nearby Cities, and similar 595 Off-Market properties to explore as potential leads, plus 2 Land Listings that present a potential for development.

    Explore Opportunities in Nearby Cities

    Here are 4 Similar properties we found in Nearby Locations for your consideration.

    Downtown Vacant Corner Lot
    $45,000

    Downtown Vacant Corner Lot

    Vacant commercial lot in downtown area with high traffic.

    651 State St, Chester, IL 62233
    View details
    Historic Mixed-Use Building in Chester
    $180,000
    5,720 SF

    Historic Mixed-Use Building in Chester

    Historic mixed-use building with retail and residential income potential.

    104-106 W Stacey St, Chester, IL 62233
    View details
    Multi-Use Land Tract For Sale
    $429,000
    40.00 Acres

    Multi-Use Land Tract For Sale

    40-acre tract near Oak Ridge, MO, suitable for farming, recreation.

    State Hwye, Oak Ridge, MO 63769
    View details
    Turn-Key Restaurant Business Opportunity
    $200,000
    2,760 SF

    Turn-Key Restaurant Business Opportunity

    Fully operational restaurant, ready for new owner in Oak Ridge.

    4053 State Hwy E, Oak Ridge, MO 63769
    View details

    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

    Prime Commercial Land, Perryville, MO
    $972,000
    0.94 Acres

    Prime Commercial Land, Perryville, MO

    0.94 acre commercial land with high traffic and development potential.

    1324 W Saint Joseph St, Perryville, MO 63775
    View details
    Highway 51 Commercial Land Available
    $980,000

    Highway 51 Commercial Land Available

    10 acres of commercial land with high visibility.

    Highway 51, Perryville, MO 63775
    View details

    Explore Off-Market Properties in Perryville, MO

    Consider similar Off-Market properties in Perryville, MO. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

    Veterans Memorial Pkwy

    Veterans Memorial Pkwy

    Commercial real estate • 9.45 Acres
    Value Estimation by Request
    Veterans Memorial Pkwy, Perryville, MO 63775
    View details
    221 Saint Joseph St

    221 Saint Joseph St

    Commercial real estate • 0.36 Acres
    Value Estimation by Request
    221 Saint Joseph St, Perryville, MO 63775
    View details
    1 Cinque Hommes Dr

    1 Cinque Hommes Dr

    Commercial real estate • 5.12 Acres
    Value Estimation by Request
    1 Cinque Hommes Dr, Perryville, MO 63775
    View details
    Corporate Park

    Corporate Park

    Commercial real estate • 2.44 Acres
    Value Estimation by Request
    Corporate Park, Perryville, MO 63775
    View details
    Redbud Ct

    Redbud Ct

    Commercial real estate • 5.61 Acres
    Value Estimation by Request
    Redbud Ct, Perryville, MO 63775
    View details
    Highway 51

    Highway 51

    Commercial real estate • 5.81 Acres
    Value Estimation by Request
    Highway 51, Perryville, MO 63775
    View details
    2015-2021 Jefferson St

    2015-2021 Jefferson St

    Neighborhood centers • 9,714 SF
    Value Estimation by Request
    2015-2021 Jefferson St, Perryville, MO 63775
    View details
    Main St

    Main St

    Commercial real estate • 2.39 Acres
    Value Estimation by Request
    Main St, Perryville, MO 63775
    View details
    1501 Alma Ave

    1501 Alma Ave

    Commercial real estate • 18.44 Acres
    Value Estimation by Request
    1501 Alma Ave, Perryville, MO 63775
    View details
    875 Pcr 500

    875 Pcr 500

    Office Properties & Spaces • 6,854 SF
    Value Estimation by Request
    875 Pcr 500, Perryville, MO 63775
    View details
    1100 Cinque Hommes Dr

    1100 Cinque Hommes Dr

    Commercial real estate • 17.38 Acres
    Value Estimation by Request
    1100 Cinque Hommes Dr, Perryville, MO 63775
    View details
    1120 Star St

    1120 Star St

    RECYCLING (METAL, PAPER, GLASS) • 2,920 SF
    Value Estimation by Request
    1120 Star St, Perryville, MO 63775-1571
    View details
    3478 Hwy T T

    3478 Hwy T T

    WAREHOUSE, STORAGE • 1,740 SF
    Value Estimation by Request
    3478 Hwy T T, Perryville, MO 63775-6503
    View details
    340 Jackson St

    340 Jackson St

    WAREHOUSE, STORAGE • 1,176 SF
    Value Estimation by Request
    340 Jackson St, Perryville, MO 63775-2521
    View details

    Perryville, MO Commercial Real Estate Investment Opportunities Market Analysis

    Explore 507 commercial real estate investment opportunities in Perryville, MO with 10 listings featured on our commercial real estate marketplace. The current inventory includes 70,373,960 square feet of properties with an estimated value of $81,909,658.

    Estimated prices for commercial real estate in Perryville, MO begin at $30,000, with an average of $347,074 and extend to $3,030,000.

    In Perryville, MO, current investment values show:

    • Industrial properties positioned at $338,802
    • Retail properties measuring $368,870
    • Other warehouses assessed at $292,553
    • Warehouses calculated at $292,553
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    Browse Commercial real estate for Sale Near Perryville, MO

    Popular Searches in Perryville, MO

    Most Searched ZIP Codes in Perryville, MO

    • 63775
    • 63673
    • 63776

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