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    Laclede County, MO Commercial Real Estate for Sale

    172 results
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    Route 66 RV Park
    $1,150,000
    1,776 SF

    Route 66 RV Park

    28820 Us Rte 66, Lebanon, MO 65536

    Premier RV park with cottages on historic Route 66.

    • Impeccably maintained RV Park on Route 66 with 32 spacious pull‑through pad sites, each with full hook‑ups and 30/50 AMP service.
    • Includes 3 charming, rentable cottages.
    • Main building features a lounge, 3 full bathrooms, laundry room, storage, and a private apartment for an onsite manager.
    • Built in 2021 with underground utilities, an overbuilt septic system, and a private well.
    • Significant expansion potential for additional sites, cottages, a c‑store, or a bar.
    Updated: Dec 18, 2025
    View details
    Iconic Restaurant, Lounge, and Distillery
    $2,647,000
    7,564 SF

    Iconic Restaurant, Lounge, and Distillery

    221 Evergreen Pkwy, Lebanon, MO 65536

    Profitable, fully operational restaurant with high I-44 visibility.

    • Prime real estate location with I‑44 visibility.
    • Fully operational and profitable restaurant, lounge, and distillery with established legacy.
    • Large 7,500 sq ft commercial building with versatile layout including two dining areas, bar, kitchen, distillery area, offices, and conference room.
    • Recently installed solar system for enhanced energy efficiency.
    • Includes essential restaurant infrastructure: walk‑in freezer & cooler, large well‑designed kitchen, and drive‑through.
    Updated: Feb 11
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    Established Business on Highway 5
    $2,999,900
    30,000 SF

    Established Business on Highway 5

    Turnkey business opportunity with showroom, storage, and established customer base.

    19850 Houston Rd, Lebanon, MO 65536
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    Versatile Mixed-Use Property, Lebanon, MO
    $645,000
    8,400 SF

    Versatile Mixed-Use Property, Lebanon, MO

    5 acres with I-44 frontage, multiple buildings, and owner financing.

    22472 Highway Mm, Lebanon, MO 65536
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    Historic Joe Knight Building
    $989,900
    0.25 Acres

    Historic Joe Knight Building

    Landmark building in downtown Lebanon, ready for diverse ventures.

    201 W Commercial St, Lebanon, MO 65536
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    Commercial Building with Drive-Thru
    $565,000
    0.34 Acres

    Commercial Building with Drive-Thru

    1,600 SF commercial building with drive-thru and stable tenant.

    489 S Jefferson Ave, Lebanon, MO 65536
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    I-44 Frontage Multi-Use Property
    $645,000
    5.00 Acres

    I-44 Frontage Multi-Use Property

    5 acres with I-44 frontage, multiple buildings, and owner financing.

    22472 Highway Mm, Lebanon, MO 65536
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    Route 66 Commercial/Industrial Property
    $1,000,000
    15.00 Acres

    Route 66 Commercial/Industrial Property

    15+/- acres with frontage on Historic Route 66.

    1127 W Elm St, Lebanon, MO 65536
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    Route 66 Residential/Commercial Property
    $265,000
    1.33 Acres

    Route 66 Residential/Commercial Property

    Spacious property on historic Route 66 with commercial potential.

    120 W Main St, Phillipsburg, MO 65722
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    Lebanon Retail/Auto Shop Opportunity
    $174,900
    2,964 SF

    Lebanon Retail/Auto Shop Opportunity

    Versatile commercial property with garage, office, and retail potential.

    411 E Commercial St, Lebanon, MO 65536
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    Retail Property Near Downtown Lebanon
    $170,000
    4,600 SF

    Retail Property Near Downtown Lebanon

    Retail property with income potential near downtown Lebanon, Missouri.

    210 W 2Nd St, Lebanon, MO 65536
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    Historic Church Building on Two Lots
    $42,500
    0.34 Acres

    Historic Church Building on Two Lots

    Historic church building on two lots in Lebanon, Missouri.

    528 Taylor St, Lebanon, MO 65536
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    Versatile Property in Lebanon, MO
    $589,900
    12,600 SF

    Versatile Property in Lebanon, MO

    9-acre property with buildings suitable for warehousing, offices, manufacturing.

    30841 Old Highway 5, Lebanon, MO 65536
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    Lebanon, MO Investment Opportunity
    $550,000
    2,699 SF

    Lebanon, MO Investment Opportunity

    Gas station, convenience store, and campground near Bennett Springs State Park.

    11448 Highway 64, Lebanon, MO 65536
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    Versatile Commercial Property Near Highway
    $147,500
    1,440 SF

    Versatile Commercial Property Near Highway

    Commercial property suitable for various business opportunities near major highways.

    28961 Highway F, Lebanon, MO 65536
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    High-Traffic Retail/Office Building
    $750,000
    5,400 SF

    High-Traffic Retail/Office Building

    5400 SF building on 0.52 acres with high visibility.

    123 Evergreen Pkwy, Lebanon, MO 65536
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    Versatile Mixed-Use Building in Lebanon
    $244,900
    6,968 SF

    Versatile Mixed-Use Building in Lebanon

    Mixed-use property with income potential in downtown Lebanon, Missouri.

    200 W 2Nd St, Lebanon, MO 65536
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    Prime Corner Lot in Lebanon
    $599,900
    890 SF

    Prime Corner Lot in Lebanon

    Corner lot with high traffic, ideal for retail development.

    751 Lynn St, Lebanon, MO 65536
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    Turnkey Retail Opportunity in Lebanon
    $250,000
    0.54 Acres

    Turnkey Retail Opportunity in Lebanon

    15,000+ sq ft commercial property with inventory included!

    600 West Commercial St, Lebanon, MO 65536
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    Remodeled Retail Space on Route 66
    $389,900
    3,770 SF

    Remodeled Retail Space on Route 66

    3770 SF retail building with parking and income potential.

    951 W Elm St, Lebanon, MO 65536
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    Versatile Property with I-44 Frontage
    Contact for pricing

    Versatile Property with I-44 Frontage

    5 acres with manufacturing, retail, residential, and storage buildings.

    22472 Highway Mm, Lebanon, MO 65536
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    Prime Commercial Real Estate Opportunity
    Contact for pricing

    Prime Commercial Real Estate Opportunity

    Two-story mixed-use building in prime location near Lebanon High School.

    519 N Jefferson Ave, Lebanon, MO 65536
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    Versatile Commercial Property with Garage
    Contact for pricing

    Versatile Commercial Property with Garage

    Commercial property with garage, retail space, and expansion potential.

    411 E Commercial St, Lebanon, MO 65536
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    Lebanon Commercial Land - 20 Acres
    $875,000
    20.00 Acres

    Lebanon Commercial Land - 20 Acres

    Prime 20-acre commercial lot, building included.

    1100 Utah St, Lebanon, MO 65536
    View details

    Laclede County, MO Commercial Real Estate Investment Opportunities Market Analysis

    Explore 937 commercial real estate investment opportunities in Laclede County, MO with 172 listings featured on our commercial real estate marketplace. The current inventory includes 275,267,164 square feet of properties with an estimated value of $279,673,285.

    Estimated prices for commercial real estate in Laclede County, MO begin at $35,000, with an average of $644,408 and extend to $13,900,000.

    In Laclede County, MO, current investment values show:

    • Retail properties positioned at $715,345
    • Land measuring $306,750
    • Industrial properties assessed at $879,379
    • Individual retail properties calculated at $704,239
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