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    Murphysboro, IL Commercial Real Estate for Sale

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    Carbondale, IL De Soto, IL Makanda, IL
    Historic Murphysboro Event Center For Sale
    $650,000
    0.18 Acres

    Historic Murphysboro Event Center For Sale

    1329 WALNUT Street, Murphysboro, IL 62966

    Historic building in downtown Murphysboro, ideal for events and more.

    • Historic building: Old Elks Building, built in 1916, a designated local landmark in downtown Murphysboro.
    • Operating as the Murphysboro Event Center with gaming (Rosie's Gaming), full bar, and event spaces.
    • Large capacity: Supports events for up to 500 guests.
    • Includes a lounge, gaming machines, full bar, ballroom, renovated Great Hall, kitchens, lobbies, and elevator.
    • Adaptive reuse potential: suitable for banquet hall, performance venue, gallery, cultural center, conference space, or mixed‑use development.
    Updated: Oct 21, 2025
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    Commercial Lot in Murphysboro, IL
    Contact for pricing
    0.24 Acres

    Commercial Lot in Murphysboro, IL

    112 N 15th Street, Murphysboro, IL 62966

    Vacant commercial lot with storage building for business or investment.

    • Vacant commercial lot suitable for business or investment
    • Includes a storage building
    • Convenient location
    • Water available
    • Development potential
    Updated: May 6
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    Commercial Land on High-Traffic Highway
    $399,000
    5.36 Acres

    Commercial Land on High-Traffic Highway

    Commercial land available on high-traffic highway near Murphysboro Walmart.

    COUNTRY CLUB Road, Murphysboro, IL 62966
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    Versatile Commercial Space in Murphysboro
    $89,900
    1,701 SF

    Versatile Commercial Space in Murphysboro

    Adaptable commercial property suitable for various business or educational purposes.

    507 N 9th, Murphysboro, IL 62966
    View details
    Murphysboro Multifamily Portfolio Investment Opportunity
    $1,190,000
    21,996 SF

    Murphysboro Multifamily Portfolio Investment Opportunity

    27-unit, six-property multifamily portfolio in Murphysboro, Illinois for sale.

    153 Youngman Rd, Murphysboro, IL 62966
    View details
    Based on your search, we've compiled 620 Potential Opportunities for your consideration. Besides 5 Active listings in Murphysboro, IL, we suggest exploring several alternatives: 4 properties in Nearby Cities, and similar 611 Off-Market properties to explore as potential leads

    Opportunities in Nearby Cities

    Here are 4 Similar properties we found in Nearby Locations for your consideration.

    Executive Offices in Cedar Court
    $359,900
    7,786 SF

    Executive Offices in Cedar Court

    Modern, updated executive offices in premier office park.

    1160 CEDAR Court, Carbondale, IL 62901
    View details
    Commercial Lot Near Golf Course
    $100,000

    Commercial Lot Near Golf Course

    Commercial lot with high visibility near Apple Creek Golf Course.

    Lot 27 Virginia Drive, Makanda, IL 62958
    View details
    Carbondale Medical Office Building
    $489,000

    Carbondale Medical Office Building

    Adaptable medical office in premier business park.

    1235 CEDAR Court, Carbondale, IL 62901
    View details
    Remodeled Office Building Near Golf
    $429,900
    6,400 SF

    Remodeled Office Building Near Golf

    Remodeled 6400 sqft office building suitable for business or medical.

    16 Presley Park Dr, Makanda, IL 62958
    View details

    Off-Market Properties in Murphysboro, IL

    Consider similar Off-Market properties in Murphysboro, IL. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

    115 8th St

    115 8th St

    COMMERCIAL (GENERAL)
    Value Estimation by Request
    115 8th St, Murphysboro, IL 62966-2624
    View details
    17th St

    17th St

    VACANT COMMERCIAL LAND • 0.06 Acres
    Value Estimation by Request
    17th St, Murphysboro, IL 62966
    View details
    17th St

    17th St

    VACANT COMMERCIAL LAND • 0.06 Acres
    Value Estimation by Request
    17th St, Murphysboro, IL 62966
    View details
    17th St

    17th St

    VACANT COMMERCIAL LAND • 0.06 Acres
    Value Estimation by Request
    17th St, Murphysboro, IL 62966
    View details
    Murphysboro, IL 62966

    Murphysboro, IL 62966

    COMMERCIAL (GENERAL) • 0.06 Acres
    Value Estimation by Request
    Murphysboro, IL 62966
    View details
    113 12th St

    113 12th St

    COMMERCIAL (GENERAL) • 0.27 Acres
    Value Estimation by Request
    113 12th St, Murphysboro, IL 62966-2106
    View details
    430 11th St

    430 11th St

    COMMERCIAL CONDOMINUIM
    Value Estimation by Request
    430 11th St, Murphysboro, IL 62966-2178
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    110 6th St

    110 6th St

    COMMERCIAL (GENERAL)
    Value Estimation by Request
    110 6th St, Murphysboro, IL 62966-2646
    View details
    Murphysboro, IL 62966

    Murphysboro, IL 62966

    COMMERCIAL (GENERAL) • 0.53 Acres
    Value Estimation by Request
    Murphysboro, IL 62966
    View details
    Murphysboro, IL 62966

    Murphysboro, IL 62966

    VACANT COMMERCIAL LAND • 0.76 Acres
    Value Estimation by Request
    Murphysboro, IL 62966
    View details
    Murphysboro, IL 62966

    Murphysboro, IL 62966

    COMMERCIAL (GENERAL)
    Value Estimation by Request
    Murphysboro, IL 62966
    View details
    223 13th St

    223 13th St

    OFFICE (GENERAL) • 0.50 Acres
    Value Estimation by Request
    223 13th St, Murphysboro, IL 62966-2512
    View details
    Murphysboro, IL 62966

    Murphysboro, IL 62966

    COMMERCIAL (GENERAL) • 0.89 Acres
    Value Estimation by Request
    Murphysboro, IL 62966
    View details
    1106 Locust St

    1106 Locust St

    COMMERCIAL (GENERAL) • 0.04 Acres
    Value Estimation by Request
    1106 Locust St, Murphysboro, IL 62966-2119
    View details
    1904 Walnut St

    1904 Walnut St

    COMMERCIAL (GENERAL) • 0.16 Acres
    Value Estimation by Request
    1904 Walnut St, Murphysboro, IL 62966-1910
    View details
    2036 Spruce St

    2036 Spruce St

    COMMERCIAL (GENERAL) • 1.01 Acres
    Value Estimation by Request
    2036 Spruce St, Murphysboro, IL 62966-2341
    View details
    Murphysboro, IL 62966

    Murphysboro, IL 62966

    VACANT COMMERCIAL LAND
    Value Estimation by Request
    Murphysboro, IL 62966
    View details
    17 Ventura Ln

    17 Ventura Ln

    COMMERCIAL (GENERAL) • 1.79 Acres
    Value Estimation by Request
    17 Ventura Ln, Murphysboro, IL 62966
    View details
    1001 Chestnut St

    1001 Chestnut St

    OFFICE (GENERAL)
    Value Estimation by Request
    1001 Chestnut St, Murphysboro, IL 62966-2654
    View details

    Murphysboro, IL Commercial Real Estate Investment Opportunities Market Analysis

    Explore 616 commercial real estate for sale in Murphysboro, IL, showcased through 5 active listings on our real estate platform. These investment opportunities span a total of 23,697 square feet of properties for sale, with an estimated market value of $1,279,900.

    Sale prices for business properties in Murphysboro, IL start at $89,900, averaging $639,950, and reaching up to $1,190,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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    Demographics Overview

    Population 14K
    Population Growth (5Y) -8.3%
    Median Household Income $54,242
    College Educated 32.5%

    High-Yield Neighborhoods for Strategic Investment

    Identify Murphysboro submarkets with the highest inventory density on the market and evaluate the median listing prices of real estate assets

    Neighborhood Average Price
    62966 $465.8K

    Taxes & Financing

    Average Loan-to-Value 65.0%

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