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    Port Saint Lucie, FL Commercial Real Estate for Sale

    176 results
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    Established Smoke Shop For Sale
    $224,000
    1,050 SF

    Established Smoke Shop For Sale

    914 SW Gatlin Blvd, Port Saint Lucie, FL 34953

    Successful smoke shop with inventory in a prime location.

    • Established smoke shop business with a 13+ year history at this location.
    • Full inventory included in the sale.
    • Favorable lease term extending to April 30, 2028.
    • Located in a great location.
    • Central heating and central air conditioning.
    Updated: Nov 13, 2025
    View details
    Port St. Lucie Portfolio Opportunity
    $1,500,000
    0.55 Acres

    Port St. Lucie Portfolio Opportunity

    1892 SW Biltmore St, Port Saint Lucie, FL 34984

    Two adjacent income-producing commercial/residential properties in a high-growth area.

    • Portfolio of two adjacent income‑producing properties in a rapidly growing area of Port St. Lucie.
    • Combined land area of approximately 0.55 acres with excellent frontage and ample parking.
    • Fully usable fenced outdoor space suitable for various commercial or residential purposes.
    • Each property includes a single‑family structure adaptable for residential, office, or business use.
    • High‑visibility location ideal for commercial, contractor, or service‑based operations.
    Updated: Jan 4
    View details
    Turn-Key Commercial Condo in St. Lucie
    $1,300,000
    4,458 SF

    Turn-Key Commercial Condo in St. Lucie

    4500+ SF commercial condo in St. Lucie West.

    266 NW Peacock Blvd, Port Saint Lucie, FL 34986
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    Gas Station, Car Wash, Workshop
    $1,600,000

    Gas Station, Car Wash, Workshop

    Turnkey gas station, car wash, and mechanic shop in Florida.

    2780 SE Morningside Blvd, Port Saint Lucie, FL 34952
    View details
    Established Retail Business Opportunity
    $225,000

    Established Retail Business Opportunity

    Profitable appliance parts business for sale in busy location.

    8025 S Hwy 1 U.S, Port Saint Lucie, FL 34952
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    Established Carpet Cleaning Business Opportunity
    $250,000

    Established Carpet Cleaning Business Opportunity

    Profitable carpet cleaning business with strong market presence in Florida.

    Carpet Cleaning Way, Port Saint Lucie, FL 34987
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    Well-Maintained Property For Sale
    $1,290,000
    13,129 SF

    Well-Maintained Property For Sale

    Well-maintained property with long-term occupants and upside potential.

    7430-7448 S Federal Hwy, Port Saint Lucie, FL
    View details
    Port St. Lucie Flex Space
    $380,000
    2,006 SF

    Port St. Lucie Flex Space

    Industrial/flex space in a growing Port St. Lucie market.

    1556 South Niemeyer Cir, Port Saint Lucie, FL
    View details
    Port Saint Lucie Industrial Property
    $550,000
    3,600 SF

    Port Saint Lucie Industrial Property

    3,600 SF industrial property available for sale.

    12370 Lear Pl, Port Saint Lucie, FL 34987
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    Warehouse with Secure Outdoor Storage
    $1,250,000
    4,500 SF

    Warehouse with Secure Outdoor Storage

    Two-unit warehouse with secure, fenced outdoor storage near US Highway 1.

    6900 Heritage Dr, Port Saint Lucie, FL 34952
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    New 7 Brew Ground Lease
    $1,583,000
    510 SF

    New 7 Brew Ground Lease

    New construction 7 Brew with a 10-year ground lease.

    1907 SW Gatlin Blvd, Port Saint Lucie, FL 34953
    View details
    Turnkey Restaurant Opportunity For Sale
    $280,000
    956 SF

    Turnkey Restaurant Opportunity For Sale

    Fully equipped restaurant with existing inventory and engaged customer base.

    11200 SW Village Pkwy, Port Saint Lucie, FL 34987
    View details
    Baron Shoppes Shopping Plaza
    $21,500,000

    Baron Shoppes Shopping Plaza

    Fully leased shopping plaza in Port St. Lucie.

    10230-10366 S Us Hwy, Port Saint Lucie, FL
    View details
    Retail Property on US Hwy 1
    $1,300,000
    3,044 SF

    Retail Property on US Hwy 1

    Retail property with high traffic count and flexible zoning.

    130 SE Entrada Ave, Port Saint Lucie, FL 34952
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    Freestanding Service Building in Port
    $2,500,000
    11,500 SF

    Freestanding Service Building in Port

    Freestanding service building occupied by two auto-related tenants.

    1601-1607 SE Village Green Dr, Port Saint Lucie, FL 34952
    View details
    Medical Office For Sale
    $499,000
    2,041 SF

    Medical Office For Sale

    Medical office in excellent condition, well-located near major highways.

    433-481 NW Prima Vista Blvd, Port Saint Lucie, FL 34983
    View details
    Retail Property on Port St Lucie
    $2,400,000
    7,100 SF

    Retail Property on Port St Lucie

    Retail property for sale with high traffic and ample parking.

    230 SW Port St Lucie Blvd, Port Saint Lucie, FL 34984
    View details
    New Retail Center in Tradition
    $8,850,000
    14,175 SF

    New Retail Center in Tradition

    New construction retail center in booming Tradition, 100% occupancy.

    10650 Crosstown Pkwy, Port Saint Lucie, FL 34987
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    Retail Plaza & Gas Station
    $8,000,000
    9,838 SF

    Retail Plaza & Gas Station

    Retail plaza with gas station in a dense residential area.

    1293-1293 SW Del Rio Blvd, Port Saint Lucie, FL 34953
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    Port St. Lucie Flex Unit
    $375,000
    1,500 SF

    Port St. Lucie Flex Unit

    Flex unit in West Park Industrial Center for sale.

    585 NW Mercantile Pl, Port Saint Lucie, FL 34986
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    Tilt-Wall Building in Port St. Lucie
    $3,750,000
    23,756 SF

    Tilt-Wall Building in Port St. Lucie

    23,756 SF tilt-wall building on 2.3 acres for sale.

    529 NW Prima Vista Blvd, Port Saint Lucie, FL 34983
    View details
    Leased Multi-Bay Investment Opportunity
    $1,800,000
    7,000 SF

    Leased Multi-Bay Investment Opportunity

    Fully leased multi-bay property on a corner lot.

    1901 SW Biltmore St, Port Saint Lucie, FL 34984
    View details
    Retail Property For Sale
    $2,195,000
    3,856 SF

    Retail Property For Sale

    Retail property with 3,856 square feet of space available.

    10200 S Us Hwy, Port Saint Lucie, FL
    View details
    Air Conditioned Warehouse Space
    $410,000
    1,750 SF

    Air Conditioned Warehouse Space

    Air conditioned warehouse with office, mezzanine, and convenient highway access.

    575-585 NW Mercantile Pl, Port Saint Lucie, FL 34986
    View details

    Port Saint Lucie, FL Commercial Real Estate Investment Opportunities Market Analysis

    Explore 1845 commercial real estate investment opportunities in Port Saint Lucie, FL with 176 listings featured on our commercial real estate marketplace. The current inventory includes 64,528,309 square feet of properties with an estimated value of $1,168,812,861.

    Estimated prices for commercial real estate in Port Saint Lucie, FL begin at $50,000, with an average of $998,985 and extend to $27,600,000.

    In Port Saint Lucie, FL, current investment values show:

    • Industrial properties positioned at $796,112
    • Office Properties & Spaces measuring $543,988
    • Other industrial properties assessed at $437,066
    • Other office properties calculated at $277,593
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    Browse Commercial real estate for Sale Near Port Saint Lucie, FL

    Popular Searches in Port Saint Lucie, FL

    Most Searched ZIP Codes in Port Saint Lucie, FL

    • 34953
    • 34952
    • 34986
    • 34983
    • 34984
    • 34987
    • 34949
    • 34957

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