High Springs, FL Commercial real estate for sale

Updated: Aug 7

High-Clearance Warehouse With Yard

22429 S US HIGHWAY 441, High Springs, FL 32643

$885,000

6,627 sqft 4.00 AC lot

Approximately 4 acres with direct US Highway 441 frontage
Warehouse with approximately 20‑foot eave height
Five 14‑foot‑by‑12‑foot grade‑level roll‑up doors
Four‑bay covered carport and more than 30 parking spaces
Three‑bedroom, two‑bath house configured for office use

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Updated: Nov 17, 2025

Agricultural Land with Mature Pines

7818 NW STATE ROAD 45, High Springs, FL 32643

$194,000

6.53 AC lot

Mature sand pines reach 50–60 feet high
1,420 feet of frontage along NW 78th Avenue
203 feet of frontage along US Highway 41
A zoning designation
Septic system and well pump included

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Manufacturing Property with Highway Frontage

26509 W US Highway 27, High Springs, FL 32643

$1,100,000

9,000 sqft 1.90 AC lot

Functional industrial space includes warehouse, office, and showroom areas.

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Historic High Springs Commercial Building

18493 High Springs Main St, High Springs, FL 32643

$599,900

7,620 sqft 0.25 AC lot

7,620 SF commercial building in High Springs, Florida.

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Flex Space with Fenced Yard

18573 NW 246th St, High Springs, FL 32643

$349,900

1,860 sqft

Two concrete block buildings offer adaptable commercial space, parking, equipment, and C2 zoning in High Springs.

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10-Acre Estate with Income Potential

7650 NE 40TH St, High Springs, FL 32643

$638,808

1,000 sqft 5.51 AC lot

Dual-parcel estate near High Springs with pool and rental income.

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Warehouse with Four Bay Doors

26509 W US Highway 27, High Springs, FL 32643

$1,250,000

1.90 AC lot

Warehouse offers four 12’ x 14’ bay doors, 3-phase power, and an 18’ clear height with turn-key cabinetry setup.

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19-Room Hotel with Manager Apartment

19663 NW US Highway 441, High Springs, FL 32643

$2,000,000

1.96 AC lot

Hotel with 19 guest rooms plus on-site manager housing and a separate two-bedroom cottage for flexible occupancy.

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Wooded Timberland With Road Frontage

7818 NW STATE ROAD 45, High Springs, FL 32643

$194,000

6.35 AC lot

6.35-acre parcel planted with mature sand pines and improved with a septic system, well pump, and available power.

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Commercial Land with C-3 Zoning

20412 US HWY 441, High Springs, FL 32643

$399,000

C-3 zoning and available utilities support a range of potential commercial development options.

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Agricultural Land with Peanut Base

227 Th Dr, High Springs, FL 32643

$1,750,000

Contiguous agricultural acreage supports hay and grass seed production without HOA or deed restrictions.

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Medical Office Building with Five Exam Rooms

18635 NW US Hwy 441, High Springs, FL 32643

Contact for pricing

2,212 sqft 0.61 AC lot

Historic medical office on a C-3 zoned 0.61-acre lot with five exam rooms, reception, and waiting area.

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Farm With Horse Barn

3120 NE 78TH TERRACE, High Springs, FL 32643

$555,000

2,280 sqft

Upgraded mobile home with fenced pastures, equestrian improvements, and wooded recreational trails.

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C-3 Commercial Land Along US Highway

16958 Northwest US Highway 441, High Springs, FL 32643

Contact for pricing

C-3-zoned commercial land with highway frontage and multiple stated retail, food, office, and multifamily uses.

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Land

NE 32 PL, High Springs, FL 32643

$125,000

Agricultural land / Farmland

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Land

1 Northwest 222nd Street, High Springs, FL 32643

$240,000

Residential land & home lots

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Commercial Land with Highway Frontage

16817 NW HWY 441, High Springs, FL 32643

Contact for pricing

13.00 AC lot

Commercial land offering about 1,230 linear feet of frontage on US HWY 441.

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Based on your search, we've compiled Potential Opportunities for your consideration. Besides 17 Active Listings in High Springs, FL, we suggest to view alternatives - similar 55 Off-Market properties to explore as potential leads.

Off-Market Properties in High Springs, FL

Consider similar Off-Market properties in High Springs, FL. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

PARKING GARAGE, PARKING STRUCTURE

High Springs, FL 32643

Estimated value:

$440,000

20.01 AC lot

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RETAIL STORES (PERSONAL SERVICES)

18490 High Spgs Main St, High Springs, FL 32643-0521

Estimated value:

$220,000

3,636 sqft 0.30 AC lot

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NIGHTCLUB (COCKTAIL LOUNGE)

23731 Us Hwy 441, High Springs, FL 32643-1489

Estimated value:

$270,000

5,139 sqft 1.00 AC lot

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SERVICE STATION (FULL SERVICE)

18788 High Spgs Main St, High Springs, FL 32643-0094

Estimated value:

$195,000

4,560 sqft 0.48 AC lot

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OFFICE BUILDING (MULTI-STORY)

23476 186th Ave, High Springs, FL 32643-0673

Estimated value:

$485,000

2,032 sqft 0.34 AC lot

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VACANT COMMERCIAL LAND

High Springs, FL 32643

Estimated value:

$190,000

2.62 AC lot

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VACANT COMMERCIAL LAND

High Springs, FL 32643

Estimated value:

No data

0.34 AC lot

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High Springs, FL Commercial Real Estate Market Trends and Statistics

Explore 72 commercial real estate for sale in High Springs, FL, showcased through 17 active listings on our real estate platform. These investment opportunities span a total of 30,599 square feet of properties for sale, with an estimated market value of $10,280,608.

Sale prices for business properties in High Springs, FL start at $125,000, averaging $734,329, and reaching up to $2,000,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

Neighborhood	Average Price
32643	$704.6K

Neighborhood

Average Price

32643

$704.6K