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    High Springs, FL
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    High Springs, FL Commercial Real Estate for Lease

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    Alachua, FL Gainesville, FL Newberry, FL
    10 listings
    New Warehouse/Office on US Highway
    $16 SF/Yr
    1,200 SF
    New Warehouse/Office on US Highway

    17804 NW US HWY 441, High Springs, FL 32643

    New 4000 SF office/warehouse on US Highway 441.
    • High‑traffic location directly on US Highway 441, offering excellent visibility.
    • Brand new construction (completion July 2026) with 4000sf of office/warehouse space.
    • Flexible space with 1200sf of office area (4 offices, reception, etc.) and 2800sf of clear‑span warehouse.
    • Easy access to I‑75, facilitating regional transportation.
    • Warehouse features include two 10'x12' overhead doors and 14' eave heights.
    Updated: May 14
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    Retail Space on US Highway
    $64,000 SF/Yr
    1,200 SF
    Retail Space on US Highway

    17804 NW US HWY 441, High Springs, FL 32643

    Retail space available on a high-traffic US Highway.
    • New construction built in 2026
    • Central air conditioning
    • Electric heating
    • Heat pump
    • Located in Alachua County
    Updated: May 14
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    High Springs Commercial Property Rental
    $10,200/Mo
    3,600 SF
    High Springs Commercial Property Rental

    Commercial property available for rent in High Springs, Florida.

    18634 NW 231ST STREET, High Springs, FL 32643

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    Retail Space in High Springs
    Contact for pricing
    3,614 SF
    Retail Space in High Springs

    Anchor and former liquor store space available for lease.

    20303 US Hwy 441, High Springs, FL 32643

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    High Springs Retail/Office Space
    $15 SF/Yr
    8,775 SF
    High Springs Retail/Office Space

    Retail and office spaces available in High Springs, Florida.

    18646 High Springs Main St, High Springs, FL

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    Warehouse Space Near Highway 441
    Contact for pricing
    480 SF
    Warehouse Space Near Highway 441

    Warehouse space available near US Highway 441 in High Springs.

    19808 N US HIGHWAY 441, High Springs, FL 32643

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    High Springs Retail Space Available
    $15 SF/Yr
    1,403 SF
    High Springs Retail Space Available

    Retail suites available for buildout in High Springs, Florida.

    18646-18670 High Springs Main St, High Springs, FL

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    Highway Frontage Land For Lease
    Contact for pricing
    Highway Frontage Land For Lease

    Up to 5.62 acres available on Highway 441.

    16958 NW US Hwy 441, High Springs, FL

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    High Springs Retail/Office Space Available
    $15 SF/Yr
    High Springs Retail/Office Space Available

    Prime location suitable for restaurant, office, or retail buildout.

    18646 High Springs Main St, High Springs, FL 32643

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    Retail Space Available For Rent
    Contact for pricing
    13,280 SF
    Retail Space Available For Rent

    Retail spaces available, ranging from 900 to 13,280 square feet.

    20303 US-441, High Springs, FL 32643

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    Based on your search, we've compiled 28 Potential Opportunities for your consideration. Besides 10 Active listings in High Springs, FL, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities, and Similar 14 Properties for Sales.

    Commercial real estate for Lease in Nearby Cities

    Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

    Restaurant Space Available in Alachua
    $46,980 SF/Yr
    1,620 SF
    Restaurant Space Available in Alachua

    Second generation restaurant space for lease near Gainesville and I-75.

    15634 NW US HIGHWAY 441 #F, Alachua, FL 32615

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    Drive-Thru Restaurant Opportunity
    Contact for pricing
    1,880 SF
    Drive-Thru Restaurant Opportunity

    1,880 SF building with drive-thru on 1.15 AC.

    15655 Northwest US Highway 441, Alachua, FL 32615

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    Retail Space Near US Highway
    $25 SF/Yr
    1,300 SF
    Retail Space Near US Highway

    Retail space with high visibility near major transportation routes.

    16181 NW US Hwy 441, Alachua, FL

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    Retail Space on US Highway
    $23,940 SF/Yr
    1,260 SF
    Retail Space on US Highway

    Retail space available for lease on US Highway 441.

    15634 NW US HIGHWAY 441 E, Alachua, FL 32615

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    Similar Spaces for Sale in High Springs, FL

    Consider Similar Space for Sale. We found 14 Spaces matching your search parameters.

    Versatile Commercial Property in High Springs
    $349,900
    1,860 SF
    Versatile Commercial Property in High Springs

    Two-building commercial property with C2 zoning and value-add potential.

    18573 NW 246TH STREET, High Springs, FL 32643

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    Equestrian Property with Renovated Home
    $385,000
    1,352 SF
    Equestrian Property with Renovated Home

    Move-in ready 5-acre equestrian property with renovated 3-bedroom home.

    26707 NW 84TH PLACE, High Springs, FL 32643

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    C2 Zoned Development Land
    $174,900
    1.47 Acres
    C2 Zoned Development Land

    1.47-acre C2-zoned parcel offering flexible commercial and residential development uses.

    US HIGHWAY 27, High Springs, FL 32643

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    High Springs Commercial Property
    $349,900
    3,036 SF
    High Springs Commercial Property

    Two-building commercial property with fenced yard and flexible zoning.

    18573 NW 246TH St, High Springs, FL 32643

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    19-Room Hotel with Manager Apartment
    $2,000,000
    1.96 Acres
    19-Room Hotel with Manager Apartment

    Hotel with 19 guest rooms plus on-site manager housing and a separate two-bedroom cottage for flexible occupancy.

    19663 NW US Highway 441, High Springs, FL 32643

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    High Springs Office Building For Sale
    $272,000
    1,159 SF
    High Springs Office Building For Sale

    Office building with highway visibility, suitable for many businesses.

    18245 NW US HIGHWAY 441, High Springs, FL 32643

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    10-Acre Estate with Income Potential
    $638,808
    1,000 SF
    10-Acre Estate with Income Potential

    Dual-parcel estate near High Springs with pool and rental income.

    7650 NE 40TH St, High Springs, FL 32643

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    6.35 Acres Between Newberry and High Springs
    $194,000
    6.53 Acres
    6.35 Acres Between Newberry and High Springs

    6.35 acres with mature trees, flexible use, excellent access.

    7818 NW STATE ROAD 45, High Springs, FL 32643

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    Historic Medical Office Building
    $364,000
    2,212 SF
    Historic Medical Office Building

    Iconic medical office building on HWY 441 in High Springs.

    18635 NW US Hwy 441, High Springs, FL

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    Exclusive Land Parcel Opportunity
    $300,000
    10.00 Acres
    Exclusive Land Parcel Opportunity

    10-acre land parcel in a private, gated community.

    Lot 11 NW 165TH Ave, High Springs, FL 32643

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    Land For Sale
    $599,900
    0.24 Acres
    Land For Sale

    Commercial land available for sale.

    18493 HIGH SPRINGS MAIN St, High Springs, FL 32643

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    36.69 AC Commercial Land
    $2,500,000
    36.69 Acres
    36.69 AC Commercial Land

    36.69 acres of commercial land for sale.

    17825 NW US Hwy 441, High Springs, FL 32643

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    High Springs Industrial Investment Opportunity
    $1,300,000
    11,992 SF
    High Springs Industrial Investment Opportunity

    11,992 SF industrial building fully leased to national tenant.

    25845 W U.S. Hwy 27, High Springs, FL 32643

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    High Springs Agricultural Land Opportunity
    $79,000
    High Springs Agricultural Land Opportunity

    Cleared, partially fenced land near Oleano State Park.

    20548 Highway 441, High Springs, FL 32643

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    High Springs, FL Commercial real estate Leasing Opportunities Market Analysis

    Explore Commercial real estate leasing options in High Springs, FL with 10 listings featured on our commercial real estate exchange. The current inventory includes 16,178 square feet of properties with an estimated lease value of $64,080.

    Estimated lease rates for Commercial real estate in High Springs, FL begin at $15 SF/Yr, with an average of $12,816 /Mo and extend to $64,000.
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