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    Santa Cruz County, AZ Commercial Real Estate for Sale

    235 results
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    Historical Building Near Border
    $300,000
    7,460 SF

    Historical Building Near Border

    185 N Grand Ave, Nogales, AZ 85621

    Historical building with business opportunities near the border.

    • Prime Location: Steps from the US‑Mexico border in a high‑traffic commercial area.
    • Historical Significance: Unique historical building constructed in 1910.
    • Multi‑Use Potential: Features three lower‑level business spaces and numerous rooms on the second story suitable for offices.
    • Strong Economic Base: Located in Nogales, a city with a diverse economy.
    • High Volume of Trade: Nogales handles a substantial portion of Mexican produce imports into the United States (37%).
    Updated: Nov 18, 2025
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    Nogales Commercial Space For Sale
    $250,000
    1,296 SF

    Nogales Commercial Space For Sale

    754 N Morley Ave, Nogales, AZ 85621

    Adaptable commercial space with high traffic flow in Nogales, Arizona.

    • Strategic location with solid traffic flow.
    • Duplex commercial space offering flexible usage options (two‑tenant, single space, or owner‑occupied with rental income).
    • Two identical offices, each with a private bathroom and step‑in shower.
    • Large covered and open hardscapes suitable for parking, car wash/detail, or open‑air market.
    • Built in 2006 with stucco construction.
    Updated: Jul 3, 2025
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    Established Retail and Office Center
    $2,400,000
    37,482 SF

    Established Retail and Office Center

    Retail and office commercial center in downtown Nogales, Arizona.

    441 N Grand Ave, Nogales, AZ 85621
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    Versatile Commercial Property in Rio Rico
    $350,000
    2,479 SF

    Versatile Commercial Property in Rio Rico

    Commercial property with multiple tenant spaces and excellent freeway visibility.

    1157 Circulo Mercado, Rio Rico, AZ 85648
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    Downtown Nogales Commercial Block Portfolio
    $6,000,000
    24,910 SF

    Downtown Nogales Commercial Block Portfolio

    Prime 1.72-acre commercial property in downtown Nogales, Arizona.

    152 N Terrace Ave, Nogales, AZ 85621
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    Nogales Warehouse For Sale
    $250,000
    4,524 SF

    Nogales Warehouse For Sale

    Warehouse in central Nogales, ideal for logistics business.

    1122 N Bankerd Ave, Nogales, AZ 85621
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    Nogales Commercial Building with Retail
    $899,999
    17,813 SF

    Nogales Commercial Building with Retail

    Commercial building with retail units and development opportunity in Nogales.

    142 N Grand Ave, Nogales, AZ 85621
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    Downtown Nogales Commercial Opportunity
    $249,999
    4,580 SF

    Downtown Nogales Commercial Opportunity

    Prime commercial property in downtown Nogales with high visibility.

    65 N Grand Ave, Nogales, AZ 85621
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    Nogales Retail Property: Prime Investment
    $250,000
    1,825 SF

    Nogales Retail Property: Prime Investment

    High-potential retail space, needs renovation.

    734 Morley Ave, Nogales, AZ 85621
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    Nogales Office Duplex - Prime Location
    $250,000
    1,296 SF

    Nogales Office Duplex - Prime Location

    Dual Office Space, High Traffic Area, Huge Parking

    754 Morley Ave, Nogales, AZ 85621
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    Prime Tubac Retail Opportunity
    $895,000
    2,390 SF

    Prime Tubac Retail Opportunity

    Historic Village, Updated Retail Space

    2 Camino Otero, Tubac, AZ 85646
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    Nogales Retail Center - High Traffic Area
    $899,999
    17,813 SF

    Nogales Retail Center - High Traffic Area

    Prime Retail Space, 6 Units, High Foot Traffic

    142 Grand Ave, Nogales, AZ 85621
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    Prime Tubac Commercial Building
    $649,900
    3,142 SF

    Prime Tubac Commercial Building

    High-Yield Investment, Fully Leased

    25 Tubac Rd, Tubac, AZ 85646
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    Sonoita Retail Space: AZ Highway 83
    $119,000
    96 SF

    Sonoita Retail Space: AZ Highway 83

    Charming Coffee Shop & Land: Prime Sonoita Location

    3115 Az-83, Sonoita, AZ 85637
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    El Alamo Plaza: Nogales Retail Center
    $3,000,000
    37,482 SF

    El Alamo Plaza: Nogales Retail Center

    Prime Nogales retail center, 37,482 sq ft, 2.06 acres.

    441 Grand Ave, Nogales, AZ 85621
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    Amado Retail & Warehouse Opportunity
    $1,500,000
    6,524 SF

    Amado Retail & Warehouse Opportunity

    High-traffic location, ample space, seller financing.

    2957 Frontage Rd, Amado, AZ 85645
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    Historic Tubac Adobe Property
    $290,000
    2,488 SF

    Historic Tubac Adobe Property

    Charming adobe, rich history, prime location.

    10 Calle Iglesia, Tubac, AZ 85646
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    Prime Tubac Plaza Retail & Apartments
    $799,000
    3,764 SF

    Prime Tubac Plaza Retail & Apartments

    Historic Tubac retail, apartments, & extra lot.

    29 Tubac Plz, Tubac, AZ 85646
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    Nogales Commercial Land Opportunity
    $249,000
    1.54 Acres

    Nogales Commercial Land Opportunity

    1.54 Acres, Prime Retail/Office Site

    1950 Congress Dr, Nogales, AZ 85621
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    Prime Nogales Office Space
    $289,900
    4,158 SF

    Prime Nogales Office Space

    Versatile building, 4,158 sq ft, 0.29 acres.

    660 Morley Ave, Nogales, AZ 85621
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    Historic Nogales Retail Building
    $300,000
    7,460 SF

    Historic Nogales Retail Building

    Prime Downtown Location, High Traffic

    185 Grand Ave, Nogales, AZ 85621
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    Downtown Nogales Mixed-Use Investment
    $899,999
    17,813 SF

    Downtown Nogales Mixed-Use Investment

    High-traffic retail building, 6 units.

    142 Grand Ave, Nogales, AZ 85621
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    Retail Location in Nogales, Arizona
    $1,477,000
    2,154 SF

    Retail Location in Nogales, Arizona

    Prime retail location near the US-Mexico border in Nogales.

    208 N Grand Ave, Nogales, AZ 85621
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    Rio Rico Commercial Building
    $325,000
    2,479 SF

    Rio Rico Commercial Building

    2,479 SF commercial building in Rio Rico, Arizona.

    1157 Circulo Mercado, Rio Rico, AZ 85648
    View details

    Santa Cruz County, AZ Commercial Real Estate Investment Opportunities Market Analysis

    Explore 999 commercial real estate investment opportunities in Santa Cruz County, AZ with 235 listings featured on our commercial real estate marketplace. The current inventory includes 428,203,902 square feet of properties with an estimated value of $300,726,787.

    Estimated prices for commercial real estate in Santa Cruz County, AZ begin at $30,000, with an average of $642,578 and extend to $13,330,000.

    In Santa Cruz County, AZ, current investment values show:

    • Industrial properties positioned at $993,423
    • Land measuring $376,280
    • Warehouses assessed at $1,088,047
    • Retail properties calculated at $594,735
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