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Pendleton, SC Commercial Real Estate for Lease

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Historic Pendleton Bank Retail Space
$3,500 / Mo

Historic Pendleton Bank Retail Space

104 Exchange St, Pendleton, SC 29670

Renovated retail space in historic Pendleton Town Square.

  • Located on the charming Pendleton Town Square, near Clemson University.
  • Historic 1910 building, formerly the Pendleton Bank, undergoing complete renovation.
  • Approximately 1,550 sq ft of space including an extended annex.
  • Historic renovation to restore authenticity while incorporating modern standards.
  • Opportunity to take advantage of historic tax credits for upfit with early commitment.
Updated: Feb 18
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Historic Building in Pendleton Square
$3,100 / Mo

Historic Building in Pendleton Square

102 Exchange St, Pendleton, SC 29670

Iconic building in vibrant Pendleton, SC, near Clemson University.

  • Prominent location on the vibrant Town Square in Pendleton, SC.
  • Historic building with planned authentic restoration and modern updates.
  • Currently leased to retail and professional office businesses, providing immediate income.
  • Close proximity to Clemson University.
  • Located in a charming town business district with restaurants, art galleries, bakeries, and gift shops.
Updated: Dec 26, 2025
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Industrial Building Near I-85
$3 SF/Yr
420,000 SF

Industrial Building Near I-85

Industrial building with heavy power, multiple docks, and ample parking.

290 Old Anderson Rd, Pendleton, SC 29670
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Industrial Property in Pendleton, SC
Contact for pricing
196,560 SF

Industrial Property in Pendleton, SC

Industrial property available for lease in Pendleton, South Carolina.

4601 Liberty Hwy, Pendleton, SC 29670
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Pendleton Industrial Warehouse Space
$3 SF/Yr
420,000 SF

Pendleton Industrial Warehouse Space

Large warehouse space available for lease or sale.

290 Old Anderson Rd, Pendleton, SC 29670
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Based on your search, we've compiled 21 Potential Opportunities for your consideration. Besides 5 Active listings in Pendleton, SC, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities, and Similar 12 Properties for Sales.

Explore Commercial real estate for Lease in Nearby Cities

Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

Commercial Space Near Pendleton High
$3,000 / Mo

Commercial Space Near Pendleton High

Commercial space available for lease near Pendleton High.

411 Bickford Cir, Anderson, SC 29625
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New Warehouse Space in Anderson
$8 SF/Yr

New Warehouse Space in Anderson

New warehouse space for lease near I-85, Exit 19.

00 Vanguard Rd, Anderson, SC 29625
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Prime Retail Space, Pickens County
Contact for pricing
76,566 SF

Prime Retail Space, Pickens County

High-traffic location, multiple units available

500 Old Greenville Hwy, Clemson, SC 29631
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Clemson Retail Space: 15,214 SF Available
Contact for pricing
44,128 SF

Clemson Retail Space: 15,214 SF Available

High-traffic Clemson retail space, ideal for multiple tenants.

107 Canoy Ln, Clemson, SC 29631
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Explore Similar Spaces for Sale in Pendleton, SC

Consider Similar Space for Sale. We found 12 Spaces in Nearby Locations matching your search parameters.

Office Space with Garage Bays
$429,900

Office Space with Garage Bays

Two-room office with three-bay garage near Highway 76.

103 Welpine Rd, Pendleton, SC 29670
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Unrestricted Land Near Highway 76
$30,000
0.25 Acres

Unrestricted Land Near Highway 76

Unrestricted 0.25 acre lot near Clemson University.

Highway 76, Pendleton, SC 29670
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Expansive Acreage in Pendleton, SC
$949,900
27.03 Acres

Expansive Acreage in Pendleton, SC

27-acre property perfect for building, retreat, or mini-farm.

00 Jolly Wingo Rd, Pendleton, SC 29670
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Industrial Building Near I-85
Contact for pricing
420,000 SF

Industrial Building Near I-85

Industrial building with heavy power, multiple docks, and ample parking.

290 Old Anderson Rd, Pendleton, SC 29670
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Industrial Land Near Michelin
$975,000
5.18 Acres

Industrial Land Near Michelin

5.18-acre industrial parcel across from Michelin on Hwy 76.

6223 Hwy 28 S, Pendleton, SC 29670
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Commercial Property Near Clemson Boulevard
$874,999

Commercial Property Near Clemson Boulevard

Commercial property for sale near Clemson Boulevard, Anderson, SC.

99 Welpine Rd, Pendleton, SC 29670
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Prime Pendleton Commercial Land Opportunity
$1,190,000

Prime Pendleton Commercial Land Opportunity

1.85-acre commercial land with high visibility and development potential.

7202-7210 Highway 76, Pendleton, SC 29670
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Pendleton Commercial Land - I-85 Visibility
$324,900
1.93 Acres

Pendleton Commercial Land - I-85 Visibility

High-traffic location, almost 2 acres, many uses.

650 Welpine Rd, Pendleton, SC 29670
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Pendleton Commercial Property - High Traffic Area
$180,000
0.47 Acres

Pendleton Commercial Property - High Traffic Area

Prime Commercial Space, High Visibility, 0.47 Acres

6219 Clemson Blvd, Pendleton, SC 29670
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Pendleton Investment Opportunity: Prime 0.73 Acres
$210,000
0.73 Acres

Pendleton Investment Opportunity: Prime 0.73 Acres

Former club, huge potential, near Clemson.

1305 Lebanon Rd, Pendleton, SC 29670
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High-Visibility Pendleton Corner Lot
$275,000
0.30 Acres

High-Visibility Pendleton Corner Lot

Prime commercial land, high traffic, Clemson proximity.

And Millwee Crk Rd, Pendleton, SC 29670
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Hwy 76 Industrial Land, Pendleton, SC
$1,600,000
5.18 Acres

Hwy 76 Industrial Land, Pendleton, SC

5.18-acre industrial lot near Michelin.

6223 Hwy 28, Pendleton, SC 29670
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Pendleton, SC Commercial real estate Leasing Opportunities Market Analysis

Explore Commercial real estate leasing options in Pendleton, SC with 17 listings featured on our commercial real estate exchange. The current inventory includes 36,590,400,000 square feet of properties with an estimated lease value of $7 SF/Yr.

Estimated lease rates for Commercial real estate in Pendleton, SC begin at $3 SF/Yr, with an average of $3 SF/Yr and extend to $3 SF/Yr.
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