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    Anderson, SC Commercial Real Estate for Lease

    79 results
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    Downtown Anderson Commercial Space For Rent
    $1,150 / Mo
    2,614 SF

    Downtown Anderson Commercial Space For Rent

    122 W Whitner St, Anderson, SC 29624

    Versatile 1,300 SF space in historic downtown Anderson.

    • Prime location in historic downtown Anderson, across from the Anderson County Courthouse.
    • Versatile 1,300 square‑foot upper‑level space suitable for office, retail, or studio.
    • Adjacent to the City Parking Garage with ample street parking available.
    • Wood flooring throughout.
    • Adaptable floor plan.
    Updated: Feb 25
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    Class A Office Space
    $3,400 / Mo

    Class A Office Space

    2315 N Main St, Anderson, SC 29621

    Professional office suite for rent in Anderson, SC.

    • Prime Main Street location ideal for high‑visibility professional business.
    • Class A office building with included maintenance, electric, and water.
    • Versatile 2,800 sq ft suite suitable for medical or professional use.
    • Functional layout with five private offices, open floor plan, two restrooms, and a kitchen area.
    • Includes a welcoming reception area and large parking space.
    Updated: Dec 9, 2025
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    Industrial Building in Anderson, SC
    $5,500 / Mo

    Industrial Building in Anderson, SC

    Industrial building suitable for wholesale distribution in Anderson, SC.

    1821 S Mcduffie St, Anderson, SC 29624
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    Retail Space Near Major Anchors
    Contact for pricing

    Retail Space Near Major Anchors

    Retail space for lease near Publix, Burlington, Walmart, Best Buy.

    3801 Clemson Blvd, Anderson, SC 29621
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    Downtown Anderson Flex Space Available
    $1,800 / Mo

    Downtown Anderson Flex Space Available

    Flex space for lease in downtown Anderson near redevelopments.

    114-118 Tribble St, Anderson, SC 29625
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    Downtown Anderson Retail Space Available
    $5,000 / Mo

    Downtown Anderson Retail Space Available

    Retail space available for lease in downtown Anderson, SC.

    151 E Church St, Anderson, SC 29624
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    Downtown Anderson Retail Space
    $2,333 / Mo

    Downtown Anderson Retail Space

    Retail space available for lease in downtown Anderson, SC.

    213 West Whitner St, Anderson, SC 29624
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    Office Space Available for Lease
    $2,500 / Mo

    Office Space Available for Lease

    Office space for lease in Anderson, South Carolina.

    100 Electric City Blvd, Anderson, SC 29621
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    Modern Office Space Available
    $500 / Mo

    Modern Office Space Available

    Updated office space with 9 offices, conference room, and breakroom.

    521 N Mcduffie St, Anderson, SC 29621
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    Renovated Office Building For Rent
    $1,300 / Mo

    Renovated Office Building For Rent

    Renovated office building with versatile space for rent.

    1311 South Murray Avenue Ext, Anderson, SC 29624
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    Office Space Near Downtown Anderson
    $1,300 / Mo

    Office Space Near Downtown Anderson

    Office suite with three private offices, reception, and kitchenette.

    1214 North Main Street Ext, Anderson, SC 29621
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    Retail Space Available for Lease
    $1,810 / Mo

    Retail Space Available for Lease

    Retail space available for lease in Anderson, South Carolina.

    2507 Whitehall Ave, Anderson, SC 29621
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    Flex Building with Office, Warehouse
    $4,000 / Mo

    Flex Building with Office, Warehouse

    Flex building with office and warehouse space for lease.

    109 Old Denver Rd, Anderson, SC 29625
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    Versatile Office/Retail Space Available
    $2,250 / Mo

    Versatile Office/Retail Space Available

    Adaptable commercial space in high-traffic Anderson corridor.

    1107 N Fant St, Anderson, SC 29621
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    Flex Building with Office/Warehouse Space
    $4,000 / Mo

    Flex Building with Office/Warehouse Space

    Flex building with office and warehouse space for lease.

    113 Old Denver Rd, Anderson, SC 29625
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    Office Spaces Available For Lease
    $500 / Mo

    Office Spaces Available For Lease

    Office spaces available for lease in Anderson, South Carolina.

    210 N Mcduffie St, Anderson, SC 29621
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    Office Space on Hwy 81
    $15 SF/Yr
    2,683 SF

    Office Space on Hwy 81

    Office space for lease near downtown Anderson and Anderson University.

    1704 E Greenville St, Anderson, SC 29621
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    Office Space Near Clemson Blvd
    $5,000 / Mo

    Office Space Near Clemson Blvd

    Strategically located office space off Anderson's premier commercial corridor.

    120 East West Pkwy, Anderson, SC 29621
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    Commercial Building Near I-85
    Contact for pricing

    Commercial Building Near I-85

    Commercial building for lease near I-85 in Anderson, SC.

    107 Hurricane Rd, Anderson, SC 29621
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    Retail Space on Clemson Blvd
    $25 SF/Yr

    Retail Space on Clemson Blvd

    5,336 SF retail building for lease on Clemson Blvd.

    4022 Clemson Blvd, Anderson, SC 29621
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    Retail Space Available For Lease
    $18 SF/Yr

    Retail Space Available For Lease

    Retail space available for lease on Clemson Blvd.

    3182 North Main Street Ext, Anderson, SC 29621
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    Industrial Building Near I-85
    $10 SF/Yr

    Industrial Building Near I-85

    8,850 SF industrial building with fenced yard near I-85.

    1046 Watkins Road Ext, Anderson, SC 29625
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    Clemson Boulevard Retail Opportunity
    $35 SF/Yr

    Clemson Boulevard Retail Opportunity

    Retail spaces available in Clemson Common Development, Anderson, SC.

    4629 Clemson Blvd, Anderson, SC 29621
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    Well-Finished Office Space Available
    $18 SF/Yr

    Well-Finished Office Space Available

    High-visibility office space with ample parking in Anderson, SC.

    1801 N Main St, Anderson, SC 29621
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    Anderson, SC Commercial real estate Leasing Opportunities Market Analysis

    Explore Commercial real estate leasing options in Anderson, SC with 243 listings featured on our commercial real estate exchange. The current inventory includes 20,262,613,540 square feet of properties with an estimated lease value of $174 SF/Yr.

    Estimated lease rates for Commercial real estate in Anderson, SC begin at $1.00 SF/Yr, with an average of $11 SF/Yr and extend to $25 SF/Yr.
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    Browse Commercial real estate for Lease Near Anderson, SC

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