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Anderson, SC Commercial Real Estate for Lease

38 results
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Downtown Anderson Commercial Space Available
$1,350 / Mo
2,614 SF

Downtown Anderson Commercial Space Available

122 W Whitner St, Anderson, SC 29624

Versatile 1,300 SF space in historic downtown Anderson.

  • Prime location in historic downtown Anderson, across from the Anderson County Courthouse.
  • Versatile 1,300 square‑foot upper‑level space suitable for office, retail, or studio.
  • Adjacent to the City Parking Garage with ample street parking available.
  • Wood flooring throughout.
  • Adaptable floor plan.
Updated: Jan 15
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Class A Office Space
$3,400 / Mo

Class A Office Space

2315 N Main St, Anderson, SC 29621

Professional office suite for rent in Anderson, SC.

  • Prime Main Street location ideal for high‑visibility professional business.
  • Class A office building with included maintenance, electric, and water.
  • Versatile 2,800 sq ft suite suitable for medical or professional use.
  • Functional layout with five private offices, open floor plan, two restrooms, and a kitchen area.
  • Includes a welcoming reception area and large parking space.
Updated: Dec 9, 2025
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Industrial Building in Anderson, SC
$5,500 / Mo

Industrial Building in Anderson, SC

Industrial building suitable for wholesale distribution in Anderson, SC.

1821 S Mcduffie St, Anderson, SC 29624
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Prime Anderson Retail Space Available
$11 SF/Yr
2,000 SF

Prime Anderson Retail Space Available

2,000 SF Retail Building - Excellent Location

1014 Whitehall Road, Anderson, SC 29651
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Market Fair Shopping Center: Prime Retail Space
Contact for pricing
33,000 SF

Market Fair Shopping Center: Prime Retail Space

33,000 SF Retail Space - Anderson County

3795 Clemson Blvd, Anderson, SC 29621
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Main Street Retail Mall Opportunity
$1.00 SF/Yr
190,000 SF

Main Street Retail Mall Opportunity

Anderson, SC Shopping Mall - 190,000 SF

3131 Main St, Anderson, SC 29621
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Schmid Plaza Road Warehouse
$3 SF/Yr
149,555 SF

Schmid Plaza Road Warehouse

Anderson, SC industrial space available

201 Schmid Plaza Rd, Anderson, SC 29624
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Anderson Retail Strip - For Lease
$10 SF/Yr
29,040 SF

Anderson Retail Strip - For Lease

High-visibility retail spaces available

1402 River St, Anderson, SC 29624
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Anderson Mall Retail Space For Lease
Contact for pricing
576,450 SF

Anderson Mall Retail Space For Lease

High-traffic retail space in Anderson, SC.

3131 Main St, Anderson, SC 29621
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Oak Point Plaza Executive Suites
$20 SF/Yr
57,107 SF

Oak Point Plaza Executive Suites

Anderson, SC Office Space Available

4120-4126 Clemson Blvd, Anderson, SC 29621
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Anderson Retail Space - Fritz Drive
Contact for pricing
15,000 SF

Anderson Retail Space - Fritz Drive

Prime Anderson SC Retail Opportunity

128 Fritz Dr, Anderson, SC 29621
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Downtown Anderson Retail Space
$10 SF/Yr
5,300 SF

Downtown Anderson Retail Space

Iconic 5,300 sqft space, prime location.

110 Greenville St, Anderson, SC 29621
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Belvedere Plaza Retail Space For Lease
Contact for pricing
151,985 SF

Belvedere Plaza Retail Space For Lease

Anderson, SC Shopping Center Opportunity

3100 Main St, Anderson, SC 29621
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Anderson SC Shopping Center
Contact for pricing
80,097 SF

Anderson SC Shopping Center

High-traffic retail space available.

3420 Clemson Blvd, Anderson, SC 29621
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Prime Anderson Office Space
$25 SF/Yr
1,212 SF

Prime Anderson Office Space

1,800 sq ft Office in High-Traffic Area

1107 Fant St, Anderson, SC 29621
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Clemson Blvd Retail Center
$15 SF/Yr
8,400 SF

Clemson Blvd Retail Center

Anderson, SC: 1,500 SF Available

4132 Clemson Blvd, Anderson, SC 29621
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Prime Anderson Industrial Space
Contact for pricing
125,000 SF

Prime Anderson Industrial Space

Modern Manufacturing/Warehouse, 125,000 SF

230 Masters Blvd, Anderson, SC 29626
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Retail Space in Power Center
Contact for pricing
1,200 SF

Retail Space in Power Center

Retail space available in a busy power center.

172 Station Dr, Anderson, SC 29621
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Retail Space in Publix Anchored Center
Contact for pricing
2,800 SF

Retail Space in Publix Anchored Center

2,800 SF retail space available in Anderson, SC.

3801 Clemson Blvd, Anderson, SC 29621
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Regional Mall Retail Space
Contact for pricing
90,750 SF

Regional Mall Retail Space

90,750 SF retail space in Anderson's main corridor.

3101-3187 N Main St, Anderson, SC 29621
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Heated Warehouse Near Clemson Boulevard
$7 SF/Yr
7,500 SF

Heated Warehouse Near Clemson Boulevard

5,000 sqft heated warehouse with office space for lease.

107 Control Dr, Anderson, SC 29625
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Office Space on Hwy 81
$15 SF/Yr
2,683 SF

Office Space on Hwy 81

Office space for lease near downtown Anderson and Anderson University.

1704 E Greenville St, Anderson, SC 29621
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121,000 SF Industrial Space Available
Contact for pricing
121,000 SF

121,000 SF Industrial Space Available

Industrial space with interstate access and laydown yard.

2 Green Tree Rd, Anderson, SC 29625
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Explore Similar Spaces for Sale in Anderson, SC

Consider Similar Space for Sale. We found 64 Spaces in Nearby Locations matching your search parameters.

Versatile Mixed-Use Commercial Property
$750,000
0.48 Acres

Versatile Mixed-Use Commercial Property

Over 5,000 sq ft commercial property with residential area.

4327 Old Mill Rd, Anderson, SC 29623
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Anderson, SC Commercial Real Estate Leasing Opportunities Market Analysis

Explore Commercial Real Estate leasing options in Anderson, SC with 102 listings featured on our commercial real estate exchange. The current inventory includes 20,780,977,540 square feet of properties with an estimated lease value of $218 SF/Yr.

Estimated lease rates for Commercial Real Estate in Anderson, SC begin at $1.00 SF/Yr, with an average of $12 SF/Yr and extend to $25 SF/Yr.

In Anderson, SC, current lease rates show:

  • Retail properties positioned at $10
  • Office Properties & Spaces measuring $15
  • Individual retail properties assessed at $12
  • Industrial properties calculated at $9
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