Defiance, OH Commercial Real Estate for Lease

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Found 14 commercial real estates for lease in Defiance, OH, averaging $41/sq ft/yr. Use lease type data to compare options faster.
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Office Suite in Brick Building
Updated: Jun 2
Office Suite in Brick Building

1018 Ralston Avenue Suite 108, Defiance, OH 43512

$2,500/Mo
1,800 sqft
Suite 108 available in a brick retail and office building
Suite 108 includes a 1,800 SF office suite
Offered at $2,500/month plus additional CAM charges (base rent plus CAM)
Building is immediately located off US 24, in the heart of Defiance
Adjacent to ProMedica Defiance Regional Hospital campus and Diehl Park across the street
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Expandable Industrial Spec Building
Updated: Jun 2
Expandable Industrial Spec Building

25940 Commerce Drive (Spec Building), Defiance, OH 43512

Contact for pricing
70,000 sqft
70,000 SF industrial spec building ready for occupancy at end of Q2 or Q3 2026
Expandable to 100,000 SF, with additional land available for future development
Includes 2,000 SF of office space, which can also be expanded
Tenant build‑out requests can be accommodated during construction
Can be food‑grade
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Office Suite
Office Suite

1018 Ralston Ave, Defiance, OH 43512

Contact for pricing
1,800 sqft

Office suite in a brick retail and office building with off-highway access in Defiance.

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Freestanding Manufacturing Building
Freestanding Manufacturing Building

1459 Quality Drive, Defiance, OH 43512

Contact for pricing
30,000 sqft 12.86 AC lot

Industrial facility with warehouse capability, rail access, and expansion potential for a rail spur.

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Freestanding Manufacturing Building
Freestanding Manufacturing Building

1459 Quality Drive, Defiance, OH 43512

Contact for pricing
30,000 sqft 12.86 AC lot

The facility has served warehouse and manufacturing functions and sits on a short-line rail line.

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Expandable Food-Grade Industrial Facility
Expandable Food-Grade Industrial Facility

25940 Commerce Dr, Defiance, OH 43512

Contact for pricing
100,000 sqft

A 70,000 SF spec industrial building with 2,000 SF of office space, expandable to 100,000 SF and divisible for flexible use.

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Office/Retail Space with Utilities Included
Office/Retail Space with Utilities Included

912 E 2nd St, Defiance, OH 43512

$350/Mo
64 sqft 0.13 AC lot

Office/retail space with handicap access, kitchenette, restrooms, and parking.

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Remodeled Retail Space for Rent
Remodeled Retail Space for Rent

300 Hopkins St, Defiance, OH 43512

$1,100/Mo
0.08 AC lot

Remodeled retail space with offices, reception, and unfinished basement.

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Defiance Retail Space For Lease
Defiance Retail Space For Lease

319 E 2 St, Defiance, OH

Contact for pricing
5,250 sqft 0.54 AC lot

Retail or office space with high visibility and ample parking.

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Mixed-Use Main and Main Building
Mixed-Use Main and Main Building

300 Clinton St, Defiance, OH 43512

Contact for pricing
13,200 sqft

Restaurant space will be built on the main floor, with new elevator service and office space planned on upper floors.

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Historic Building in Downtown Defiance
Historic Building in Downtown Defiance

300 Clinton Street, Defiance, OH 43512

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Renovated historic building with restaurant and office space.

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Retail Space in Prime Location
Retail Space in Prime Location

8959 OH-66, Defiance, OH 43512

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3,150 sqft

3,150 SF retail space in well-maintained strip center.

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Retail Space for Lease
Retail Space for Lease

1018 Ralston Ave, Defiance, OH 43512

Contact for pricing
1,800 sqft

One retail space is available for lease with approximately 1,800 square feet of space.

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Defiance Retail Space Available
Defiance Retail Space Available

1838 & 1858 E. Second Street, Defiance, OH 43512

Contact for pricing

Retail spaces for rent at 1838 & 1858 E. Second Street.

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Based on your search, we've compiled 42 Potential Opportunities for your consideration. Besides 14 Active listings in Defiance, OH, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities, and Similar 24 Properties for Sales.

Commercial real estate for Lease in Nearby Cities

Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

Retail Space with Pylon Signage
Retail Space with Pylon Signage

1409 S Defiance St, Archbold, OH 43502

Contact for pricing
3,200 sqft

Retail space with pylon signage and ample on-site parking, with options for as-is delivery or built-to-suit improvements.

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Mixed-Use Property with Shop
Mixed-Use Property with Shop

102 Monumental St, Archbold, OH 43502

Contact for pricing
9,600 sqft

Combines an upstairs residential unit with office suites and shop space in a single building.

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In-Line Retail Shops at Center
In-Line Retail Shops at Center

1247 Scott St, Napoleon, OH 43545

Contact for pricing
1,235 sqft

In-line retail shops totaling 16,659 square feet at Napoleon Centre, anchored by Chief Super Market.

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Retail Spaces Available For Rent
Retail Spaces Available For Rent

1247 Scott St, Napoleon, OH 43545

Contact for pricing
11,424 sqft

Retail spaces available, ranging from 1,200 to 11,424 sq. ft.

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Similar Spaces for Sale in Defiance, OH

Consider Similar Space for Sale. We found 24 Spaces matching your search parameters.

Free Standing Building For Rent
Free Standing Building For Rent

618 North Clinton Street, Defiance, OH 43512

Contact for pricing
14,564 sqft 1.79 AC lot

14,564 SF building with mezzanine and drive-up window.

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Shopping Center Building with Kroger Anchor
Shopping Center Building with Kroger Anchor

1836 E 2nd St, Defiance, OH 43512

Contact for pricing
23,000 sqft

Part of a Kroger-anchored shopping center with an adjacent shadow retail center that includes Fresenius.

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Commercial Site on Stadium Drive
Commercial Site on Stadium Drive

57 Stadium Drive, Defiance, OH 43512

$225,000
0.35 AC lot

Commercial land suitable for QSR or retail development.

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Prime Land Off Elliot Road
Prime Land Off Elliot Road

00 Carpenter Road, Defiance, OH 43512

$1,999,200
28.56 AC lot

Land available near high-traffic area, can divide or build.

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Prime Land Near High Traffic
Prime Land Near High Traffic

0 Domersville Road, Defiance, OH 43512

$4,740,000
60.44 AC lot

Divisible land suitable for industrial use near major roads.

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Prime Land Off High Traffic
Prime Land Off High Traffic

0 Carpenter Road, Defiance, OH 43512

$3,538,000
40.00 AC lot

Divisible land suitable for industrial use near Elliot Road.

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Industrial Specialty Property
Industrial Specialty Property

25401 Elliott Road, Defiance, OH 43512

Contact for pricing
100,000 sqft

Industrial specialty property offered for sale with approximately 100,000 SF of space.

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Industrial Specialty Property
Industrial Specialty Property

1459 Quality Drive, Defiance, OH 43512

Contact for pricing
30,000 sqft

Industrial specialty property offered for sale with 30,000 SF of space.

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Industrial Land Parcels Available
Industrial Land Parcels Available

East Commerce Dr, Defiance, OH 43512

Contact for pricing
45 sqft

45-acre industrial land with M-2 and M-3 zoning.

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Office Building With Additional Lot
Office Building With Additional Lot

1137 S Clinton St, Defiance, OH 43512

$205,000

Multiple private offices, client waiting space, staff amenities, and on-site parking support a range of business operations.

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Defiance, OH Commercial real estate Market Trends and Statistics

Explore Commercial real estate leasing options in Defiance, OH with 14 listings featured on our commercial real estate exchange. The current inventory includes 257,064 square feet of properties with an estimated lease value of $82.30.

Estimated lease rates for Commercial real estate in Defiance, OH begin at $16.67 SF/Yr, with an average of $41.15 SF/Yr and extend to $65.63 SF/Yr.
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