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    Defiance, OH Commercial Real Estate for Lease

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    Columbus, OH Cincinnati, OH Cleveland, OH
    13 results
    Retail Space in Defiance, OH
    $20 SF/Yr
    12,850 SF

    Retail Space in Defiance, OH

    8959 State Route 66 N, Defiance, OH 43512

    3,150 SF retail space available in neighborhood retail center.

    • Prime location at the signalized intersection of State Route 66 and Elliott Rd, near State Route 24 interchange.
    • High visibility with 147 ft of frontage on State Route 66.
    • Located in a strong retail corridor near Walmart, Meijer, Kohls, and other national retailers.
    • Marquee and facade signage opportunities available.
    • Ample paved parking.
    Updated: Nov 21, 2025
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    Historic Downtown Building Renovation
    Contact for pricing

    Historic Downtown Building Renovation

    300 Clinton Street, Defiance, OH 43512

    Renovated historic building with restaurant and office space.

    • Prime "Main and Main" location at the busiest intersection in downtown Defiance.
    • Major historic renovation of the building.
    • Main floor restaurant space available to be built out.
    • Potential for outdoor dining area.
    • Second and third floor office suites available to be built out.
    Updated: Mar 6
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    Historic Downtown Building Renovation
    Contact for pricing
    13,200 SF

    Historic Downtown Building Renovation

    Prime location for restaurant or office space in Defiance, OH.

    300 Clinton Street, Defiance, OH 43512
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    Free Standing Building For Rent
    Contact for pricing
    14,564 SF

    Free Standing Building For Rent

    14,564 SF building with mezzanine and drive-up window.

    618 North Clinton Street, Defiance, OH 43512
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    Industrial Facility in Defiance, Ohio
    Contact for pricing
    70,000 SF

    Industrial Facility in Defiance, Ohio

    70,000 SF industrial facility, expandable to 100,000 SF.

    25490 Commerce Drive (Spec Building), Defiance, OH 43512
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    Retail Space with High Visibility
    $20 SF/Yr
    3,150 SF

    Retail Space with High Visibility

    Retail space with frontage on State Route 66.

    8959 OH-66, Defiance, OH
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    Retail Space Near Kroger
    $8 SF/Yr
    9,217 SF

    Retail Space Near Kroger

    Retail space available in shadow-anchored shopping center.

    1838-1858 E 2nd St, Defiance, OH
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    Defiance Office Space Available
    $8 SF/Yr
    6,000 SF

    Defiance Office Space Available

    6,000 square feet of office space for rent.

    24862 Elliott Rd, Defiance, OH
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    Defiance Retail Space For Lease
    Contact for pricing
    5,250 SF

    Defiance Retail Space For Lease

    Retail or office space with high visibility and ample parking.

    319 E 2 St, Defiance, OH
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    Historic Building in Downtown Defiance
    Contact for pricing

    Historic Building in Downtown Defiance

    Renovated historic building with restaurant and office space.

    300 Clinton Street, Defiance, OH 43512
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    Retail Space in Prime Location
    Contact for pricing
    3,150 SF

    Retail Space in Prime Location

    3,150 SF retail space in well-maintained strip center.

    8959 OH-66, Defiance, OH 43512
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    Modern Retail/Office Center For Rent
    Contact for pricing
    20,056 SF

    Modern Retail/Office Center For Rent

    20,056 SF retail/office center constructed in 2013.

    100 Stadium Drive, Defiance, OH 43512
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    Defiance Retail Space Available
    Contact for pricing

    Defiance Retail Space Available

    Retail spaces for rent at 1838 & 1858 E. Second Street.

    1838 & 1858 E. Second Street, Defiance, OH 43512
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    Based on your search, we've compiled 30 Potential Opportunities for your consideration. Besides 13 Active listings in Defiance, OH, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities, and Similar 13 Properties for Sales.

    Explore Commercial real estate for Lease in Nearby Cities

    Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

    Industrial Building in Napoleon, Ohio
    $3 SF/Yr
    49,409 SF

    Industrial Building in Napoleon, Ohio

    49,409 SF industrial building available for lease or sale.

    600 Fillmore St, Napoleon, OH 43545
    View details
    Wauseon Industrial Property for Lease
    $4 SF/Yr
    135,000 SF

    Wauseon Industrial Property for Lease

    135,000 SF industrial property featuring office and lab space.

    535 W Linfoot St, Wauseon, OH
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    Retail Space Near Walmart
    Contact for pricing
    1,200 SF

    Retail Space Near Walmart

    Retail space available near Walmart Supercenter.

    470 Airport Hwy, Wauseon, OH
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    Retail Spaces Available For Rent
    Contact for pricing
    11,424 SF

    Retail Spaces Available For Rent

    Retail spaces available, ranging from 1,200 to 11,424 sq. ft.

    1247 Scott St, Napoleon, OH 43545
    View details

    Explore Similar Spaces for Sale in Defiance, OH

    Consider Similar Space for Sale. We found 13 Spaces matching your search parameters.

    Commercial Site on Stadium Drive
    $225,000

    Commercial Site on Stadium Drive

    Commercial land suitable for QSR or retail development.

    57 Stadium Drive, Defiance, OH 43512
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    In-Line Shopping Center For Sale
    Contact for pricing
    20,056 SF

    In-Line Shopping Center For Sale

    20,056 SF shopping center with move-in ready suites.

    100 Stadium Dr, Defiance, OH 43512
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    Commercial Site on Stadium Drive
    $225,000

    Commercial Site on Stadium Drive

    Prime commercial land suitable for QSR, retail, and drive-thru concepts.

    57 Stadium Drive, Defiance, OH 43512
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    Industrial Land Parcels Available
    Contact for pricing

    Industrial Land Parcels Available

    45-acre industrial land with M-2 and M-3 zoning.

    East Commerce Dr, Defiance, OH 43512
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    Highway Exposure Industrial Land
    $181,320
    3.02 Acres

    Highway Exposure Industrial Land

    Fully developed industrial land ready for construction with highway exposure.

    167 Fox Run Dr, Defiance, OH
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    Industrial Land in Northwest Ohio
    Contact for pricing
    45.00 Acres

    Industrial Land in Northwest Ohio

    Industrial land for sale in Defiance, Ohio.

    East Commerce Dr, Defiance, OH
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    Industrial Land with Highway Exposure
    $120,000
    2.00 Acres

    Industrial Land with Highway Exposure

    Highway-exposed, fully developed industrial land ready for construction.

    83 Fox Run Dr, Defiance, OH
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    Prime Commercial Land Opportunity
    $250,000
    2.12 Acres

    Prime Commercial Land Opportunity

    2.12 acre commercial land for sale in Defiance, OH.

    575 Cleveland Ave, Defiance, OH
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    Commercial Land Next to Kohl's
    $500,000

    Commercial Land Next to Kohl's

    1.02 acres of commercial land for sale.

    8683 N Clinton St, Defiance, OH 43512
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    Industrial Land Parcels Available
    Contact for pricing

    Industrial Land Parcels Available

    Industrial land for sale with build-to-suit options.

    East Commerce Dr, Defiance, OH 43512
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    Industrial Land Ready For Construction
    Contact for pricing

    Industrial Land Ready For Construction

    Fully developed industrial land with highway exposure and all utilities.

    83 Fox Run Dr, Defiance, OH 43512
    View details

    Defiance, OH Commercial real estate Leasing Opportunities Market Analysis

    Explore Commercial real estate leasing options in Defiance, OH with 13 listings featured on our commercial real estate exchange. The current inventory includes 800,066,520 square feet of properties with an estimated lease value of $36 SF/Yr.

    Estimated lease rates for Commercial real estate in Defiance, OH begin at $8 SF/Yr, with an average of $12 SF/Yr and extend to $20 SF/Yr.
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