Onondaga County, NY Commercial Real Estate for Lease

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Restored Office Building in Syracuse
Restored Office Building in Syracuse

358 W Jefferson St, Syracuse, NY

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15,000 sqft 0.84 AC lot

Restored office building with parking near Armory Square.

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Retail Space with Included Utilities
Retail Space with Included Utilities

4455 East Genesee Street, Syracuse, NY 13214

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Commercial space with taxes, exterior maintenance, electric, and water included.

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Retail Space with Signalized Access
Retail Space with Signalized Access

2803 Brewerton Rd, Syracuse, NY 13211

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631 sqft

Retail space with signalized access from Brewerton Rd, providing convenient connectivity to I-81 and surrounding retailers.

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Available Office Space For Rent
Available Office Space For Rent

103 Commerce Blvd, Liverpool, NY

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18,190 sqft 4.69 AC lot

Office space with open layout and excellent location for rent.

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Medical Office Suites
Medical Office Suites

5100 W Taft Rd, Liverpool, NY 13088

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1,490 sqft

Medical office suites are available with 24-hour access and ample parking.

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Freestanding Office Building
Freestanding Office Building

2401 - 2425 James Street, Syracuse, NY 13206

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Office building for rent on James Street in Syracuse’s Eastwood neighborhood, with access to regional transportation corridors.

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Empire Plaza Retail Space Available
Empire Plaza Retail Space Available

3150 Erie Blvd E, Dewitt, NY

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19,282 sqft 13.08 AC lot

19,282+/- SF in-line space for rent in Empire Plaza.

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Former KFC on Oswego Rd
Former KFC on Oswego Rd

7601 Oswego Rd, Liverpool, NY 13090

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High-traffic location near Wegmans and Target, ideal for retail.

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Retail Space on Brewerton Road
Retail Space on Brewerton Road

3800 Brewerton Rd, Syracuse, NY

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1,500 sqft 1.50 AC lot

Retail space available for lease in Syracuse, NY.

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Warehouse with Fenced Outdoor Storage
Warehouse with Fenced Outdoor Storage

6159 E Molloy Rd, East Syracuse, NY

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5,500 sqft 1.67 AC lot

Warehouse space available January 2026 with ample outdoor storage.

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Furnished Office Space Near Universities
Furnished Office Space Near Universities

18 Arbor Ln, Syracuse, NY

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400 sqft 2.96 AC lot

Furnished office space with private entrance and on-site parking.

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Office Building with Loading Dock
Office Building with Loading Dock

4100 Medical Center Dr, Fayetteville, NY 13066

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901 sqft

Office building with 24-hour access, large common conference/event room, and loading dock with freight elevator.

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Office Spaces in State Tower
Office Spaces in State Tower

109 S Warren St, Syracuse, NY 13202

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1,003 sqft

Contiguous office suites up to 5,285 SF within a mixed-use tower featuring a 24/7 lobby attendant and attached garage.

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Corner Retail or Office Space
Corner Retail or Office Space

4001 South Salina Street, Syracuse, NY 13205

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Corner commercial space on South Salina Street with CM zoning supporting multiple retail, office, and restaurant uses.

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Retail Space
Retail Space

102 3rd Street, East Syracuse, NY 13057

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Retail premises in a building constructed for commercial use.

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Renovated Office Space Available
Renovated Office Space Available

4 Adler Dr, East Syracuse, NY 13057

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Flexible, renovated office suites with ample parking and modern amenities.

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Office/Medical Building, Spring 2025
Office/Medical Building, Spring 2025

820 Franklin Park Dr, East Syracuse, NY

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7,000 sqft 0.90 AC lot

7,000 SF office/medical building to be constructed Spring 2025.

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Single-Story Flex Suite
Single-Story Flex Suite

13 Dwight Park Drive, Syracuse, NY 13209

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Gross lease space combines warehouse loading with dedicated office area.

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Two-Story Flex Space
Two-Story Flex Space

401-423 W Taylor St, Syracuse, NY 13202

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5,000 sqft

Two-story flex space with recent building improvements in an industrial area outside the Syracuse CBD.

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Turnkey Medical Office Space Available
Turnkey Medical Office Space Available

127-29 Seeley Rd, Syracuse, NY 13224

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0.62 AC lot

Professionally renovated medical office with suites, kitchen, and ample parking.

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Medical Office Building with Shared Lobby
Medical Office Building with Shared Lobby

2108- 2122 Erie Boulevard East, Syracuse, NY 13224

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Three medical and professional office suites offer flexible layouts with patient and staff parking on site.

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Renovated Office Space For Rent
Renovated Office Space For Rent

831 James Street, Syracuse, NY 13203

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Newly renovated office space in a highly visible Syracuse location.

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Warehouse with Fenced Storage Yard
Warehouse with Fenced Storage Yard

133 W Seneca St, Manlius, NY 13104

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2,550 sqft

A 2,550 sf warehouse includes a fenced yard and sits on over 2 acres suitable for redevelopment.

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Industrial Property with Dismantler License
Industrial Property with Dismantler License

17 Dippold Ave, Salina, NY 13208

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4.27 AC lot

Turnkey industrial property with NYS dismantler and inspection license.

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