East Islip, NY Commercial real estate for Rent & Lease

Updated: Jul 28

Shopping Center

310 East Main Street, East Islip, NY 11730

Contact for pricing

60,000 sqft

Listed as a 60,000 SF shopping center
Property size listed as 1,680 SF
Located on East Main Street
Just west of Southern State Parkway and Heckscher Parkway
East Islip, NY 11730

View details

Updated: Nov 21, 2025

Retail Space on Main Street

75-77 W Main St, East Islip, NY 11730

$30.72 SF/Yr

Prime downtown location with excellent visibility and strong foot traffic.
Ideal for a variety of retail businesses due to high‑traffic area and accessibility.
Perfect for food service and other wet use with new grease trap being installed and connection to sewers.
Located in a prestigious south shore hamlet along the great south bay.
1,250 SF retail space available.**

View details

Retail Space on Main Street

75 W Main St, East Islip, NY

Contact for pricing

1,250 sqft 0.10 AC lot

1,250 SF retail space for lease on Main Street.

View details

Turn a Listing Into an Investment Snapshot Cap Rate, Potential NOI, Demand score for every listing. Go To Analytics Center

Sunrise Highway Retail Opportunity

2650 Sunrise Highway, East Islip, NY 11730

Contact for pricing

Prime East Islip retail space with high visibility.

View details

Shopping Center

310 E Main St, East Islip, NY 11730

Contact for pricing

2,224 sqft

Shopping center on East Main Street just west of Southern State Parkway/Heckscher Parkway, offered for rent.

View details

Based on your search, we've compiled 14 Potential Opportunities for your consideration. Besides 5 Active listings in East Islip, NY, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities, and Similar 5 Properties for Sales.

Commercial real estate for Lease in Nearby Cities

Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

Street-Level Storefront Space

472 Main St, Islip, NY 11751

$2,875/Mo

Prominent display windows provide natural light, signage exposure, and direct sidewalk access.

View details

Medical Office Suite with Parking

1420 Montauk Highway, Oakdale, NY 11769

$950/Mo

0.08 AC lot

Medical-zoned office space on Montauk Highway with dedicated parking and flexible furnished or unfurnished delivery.

View details

Medical Office Suite with Parking

1420 Montauk Highway, Oakdale, NY 11769

$1,000/Mo

0.08 AC lot

Medical zoning supports healthcare, counseling, and wellness-oriented professional services.

View details

Industrial Land

2 Beaver Dam Rd, Islip, NY 11751

Contact for pricing

8,000 sqft

Industrial land in the Town of Islip with planned warehouse construction and striped parking shown on the site plan.

View details

Similar Spaces for Sale in East Islip, NY

Consider Similar Space for Sale. We found 5 Spaces matching your search parameters.

Medical Office with Basement

3250 Sunrise Highway, East Islip, NY 11730

$699,999

0.31 AC lot

Configured with reception, waiting areas, exam rooms, administrative workstations, and separate patient and staff entrances.

View details

Renovated Multi-Tenant Office Building

128 Carleton Avenue, East Islip, NY 11730

$800,000

0.28 AC lot

Fully occupied office property with updated shared amenities, a detached storage garage, and flexible multi-tenant configuration.

View details

Professional Office Condominium

369 E Main Street, East Islip, NY 11730

$309,000

0.02 AC lot

Configured with private offices, a conference room, reception area, storage, and a private restroom.

View details

Office Building with Expansion Potential

55 Carleton Avenue, East Islip, NY 11730

$1,650,000

0.98 AC lot

GSD-zoned office property with public water, public sewer, and access to central air conditioning.

View details

Medical Office with Basement

3250 Sunrise Highway, East Islip, NY 11730

$699,999

0.31 AC lot

Clinical layout includes reception, waiting areas, exam rooms, and dedicated administrative workstations.

View details

East Islip, NY Commercial real estate Market Trends and Statistics

Explore Commercial real estate leasing options in East Islip, NY with 5 listings featured on our commercial real estate exchange. The current inventory includes 63,474 square feet of properties with an estimated lease value of $30.72.

Estimated lease rates for Commercial real estate in East Islip, NY average $30.72 SF/Yr.