Dona Ana County, NM Commercial real estate for Rent & Lease

Updated: Jul 26

Three-Office Professional Suite

344 S San Pedro Street, Las Cruces, NM 88001

$1,152/Mo

0.23 AC lot

987‑square‑foot office suite with 3 office spaces
Reception area, kitchenette, storage/file room, and utility closet
ADA‑compliant restroom
Central air conditioning and natural‑gas heating
344 S San Pedro Street location near Downtown, courthouses, City Hall, and other government offices

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Updated: Jul 15

Fenced Mixed-Use Commercial Building

215 Bryant Street, Mesquite, NM 88048

$1,932/Mo

0.47 AC lot

0.47‑acre fenced and gated commercial parcel
Mixed‑use building with secure reception and administrative office space
ADA‑compliant features and ceramic tile flooring
Two blocks from HWY 478 and one block from rail service
Agricultural commercial district near Helena Ag products, John Deere, and a rail‑served processing station

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Secure Heavy-Industrial Flex Space

1430-1 E Thorpe Road, Las Cruces, NM 88012

$3,500/Mo

2.50 AC lot

Fenced industrial grounds include an operations center, offices, support areas, and a gated yard suitable for truck access.

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Executive Office Suites

333 S Campo St, Las Cruces, NM 88001

$750/Mo

3,000 sqft

Move-in-ready executive office suites offer a professional reception area and modern finishes within a Class A environment.

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Flex Space With Office Garage

1712 N Main Street, Las Cruces, NM 88001

$2,108/Mo

1.43 AC lot

Lease opportunity combining professional offices, loading access, and functional garage space for integrated business operations.

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Updated Medical Office Suite

1855 E Lohman Avenue, Las Cruces, NM 88001

$1,950/Mo

0.55 AC lot

Flexible layout includes reception, treatment rooms, break area, and restroom.

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Gated Mixed-Use Commercial Property

1150 E Berino Road, Mesquite, NM 88048

$1,712/Mo

1.08 AC lot

Fenced grounds, secure reception, and an ADA-compliant layout support varied commercial operations.

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Fenced Flex Space with Offices

855 B W Picacho Ave, Las Cruces, NM 88005

$11 SF/Yr

1,428 sqft

Office-oriented flex space with kitchen, conference room, patios, gated yard, and ADA accessibility.

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Fenced Flex Industrial Property

1430 E Thorpe Rd, Las Cruces, NM 88012

$2,500/Mo

1.00 AC lot

Secure, gated industrial space offers multiple work areas, reception, restroom, break area, and a fenced courtyard.

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Warehouse Building for Lease

1920 Appaloosa Drive, Sunland Park, NM 88063

$10,000/Mo

1.70 AC lot

Warehouse space available for lease in an M1-zoned commercial area.

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Flex Space with Secured Yard

848 W Hadley Ave, Las Cruces, NM 88005

$4,500/Mo

6,750 sqft

M-1-zoned office and warehouse facility with private offices, reception space, and protected outdoor storage.

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Retail Suite with C2 Zoning

1900 S Telshor Boulevard, Las Cruces, NM 88011

$1,350/Mo

0.37 AC lot

Single-story space includes two rooms, a bathroom, utility sink, central refrigerated air, and ample parking.

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Two-Bay Drive-Through Auto Shop

2001 S Valley Drive, Las Cruces, NM 88005

$3,000/Mo

0.04 AC lot

Stand-alone quick-lube facility includes a scissor lift and full basement equipment area.

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Professional Office Suite

2-344 S San Pedro St, Las Cruces, NM 88001

$1,151/Mo

987 sqft

Functional office layout with reception, storage, an ADA-compliant restroom, and kitchenette.

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Six-Unit Apartment Building

506 E May Avenue, Las Cruces, NM 88001

$600,000/Mo

0.39 AC lot

Remodeled apartment property near Downtown Las Cruces with varied residential layouts.

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Updated Medical Office Suite

G-1855 E Lohman Ave, Las Cruces, NM 88001

$1,950/Mo

1,200 sqft

Professionally updated office suite for lease with reception, four rooms, break area, and restroom.

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Flexible Office-Retail Space

665 E University Ave, Las Cruces, NM 88005

$18.65 SF/Yr

5,900 sqft

Open work areas, showrooms, and private offices support both office and retail operations.

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Flex Space with Office Areas

2001 Copper Loop, Las Cruces, NM 88005

$1,000/Mo

47,410 sqft

Office and warehouse components support a range of commercial space requirements.

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Fenced-Yard Flex Space

1430 4 Thorpe Rd, Las Cruces, NM 88012

$12.62 SF/Yr

2,376 sqft 2.50 AC lot

I3-zoned flex property with secured outdoor storage, truck access, and an on-site operations center.

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Adaptable Retail Space

2215 S. Main Street, Las Cruces, NM 88005

$10 SF/Yr

64,665 sqft

The 1959-built facility has accommodated retail and office-oriented uses.

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Office Suite with Showers

2407 W Picacho Ave, Las Cruces, NM 88007

$11 SF/Yr

1,500 sqft

Lower-level office space includes two bathrooms with showers, shared conference access, covered parking, and utilities.

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Stand-Alone Office Suite

520 N Campo St, Las Cruces, NM 88001

$15.21 SF/Yr

986 sqft

Gated private office with a customer waiting area, mini-split climate control, and vinyl plank flooring.

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Grey Shell Office/Retail Suites

B-4104 Sonoma Ranch Blvd, Las Cruces, NM 88011

$4,600/Mo

3,680 sqft

Clear-span building offers office, retail, or medical suites in grey shell condition with tenant improvement allowance and parking.

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Private Medical Office Space

2145 El Paseo Rd, Las Cruces, NM 88001

$500/Mo

2,148 sqft

Confidential office setting with private rooms, client waiting space, and ADA-compliant access.

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Dona Ana County, NM Commercial real estate Market Trends and Statistics

Explore Commercial real estate leasing options in Dona Ana County, NM with 109 listings featured on our commercial real estate exchange. The current inventory includes 1,397,188 square feet of properties with an estimated lease value of $495.31.

Estimated lease rates for Commercial real estate in Dona Ana County, NM begin at $2.79 SF/Yr, with an average of $16.51 SF/Yr and extend to $38 SF/Yr.