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    Des Peres, MO Commercial Real Estate for Lease

    12 results
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    Prime Land for Development
    Contact for pricing

    Prime Land for Development

    13205 Manchester Rd, Des Peres, MO 63131

    2 acres available in busy retail corridor near I-270.

    • High traffic location on Manchester Road (70,000+ vehicles per day).
    • Strong co‑tenants including Shake Shack, Panera, Chipotle, and Trader Joe’s.
    • Strong demographics with high average income ($174,273 within 3 miles).
    • Approximately 2 acres available for development.
    • Close proximity to Interstate 270 (1 mile) with high traffic (167,000+ vehicles per day).
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    Des Peres Office Space Available
    Contact for pricing
    2,079 SF

    Des Peres Office Space Available

    13100 Manchester Rd, Des Peres, MO 63131

    Office space for rent in a convenient location.

    • Convenient Manchester/I‑270 Location
    • Abundant Parking
    • Common Corridors Recently Updated
    • Near Restaurants, West County Mall, Trader Joe’s & St. Louis Bread Company
    • Last Suite Available
    Updated: Dec 3, 2025
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    Des Peres Retail Space Available
    Contact for pricing
    5,335 SF

    Des Peres Retail Space Available

    Retail space in high-traffic Des Peres location for lease.

    12340-12360 Manchester Rd, Des Peres, MO 63131
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    Retail Space Near West County
    Contact for pricing
    1,080 SF

    Retail Space Near West County

    Retail space with major renovations and high traffic location.

    1131-1193 Colonnade Ctr, Des Peres, MO
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    Retail and Office Space Available
    Contact for pricing
    163 SF

    Retail and Office Space Available

    Mixed-use building with retail, office, and lower level space.

    12005-12085 Manchester Rd, Des Peres, MO 63131
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    Des Peres Retail Space For Lease
    Contact for pricing
    2,186 SF

    Des Peres Retail Space For Lease

    Prime Des Peres location, 2186 sq ft retail space.

    12100 Manchester Rd, Des Peres, MO 63131
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    Des Peres Medical Office Building
    $20 SF/Yr
    48,000 SF

    Des Peres Medical Office Building

    Class A, 1,989 SF Available

    2315 Dougherty Fry Rd, Des Peres, MO 63131
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    Retail Space in Des Peres
    Contact for pricing
    1,396 SF

    Retail Space in Des Peres

    Retail space available in a shopping center in Des Peres.

    11925-11955 Manchester Rd, Des Peres, MO 63122
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    Des Peres Corners Retail Space
    Contact for pricing
    120,673 SF

    Des Peres Corners Retail Space

    Prime St. Louis County retail, multiple spaces available.

    12332 Manchester Rd, Des Peres, MO 63131
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    Retail Space in Des Peres
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    3,164 SF

    Retail Space in Des Peres

    Retail space available in Olympic Oaks Village, Des Peres, MO.

    12107-12129 Manchester Rd, Des Peres, MO 63122
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    Retail Space in Des Peres
    Contact for pricing
    1,386 SF

    Retail Space in Des Peres

    Retail space available at a high-traffic intersection.

    1052-1090 N Ballas Rd, Des Peres, MO
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    Medical Office Space Available
    Contact for pricing
    13,515 SF

    Medical Office Space Available

    Medical office space for lease in Des Peres, Missouri.

    1000 Des Peres Rd, Des Peres, MO
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    Based on your search, we've compiled 16 Potential Opportunities for your consideration. Besides 12 Active listings in Des Peres, MO, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities

    Explore Commercial real estate for Lease in Nearby Cities

    Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

    Office Space with Building Amenities
    $28 SF/Yr
    28,375 SF

    Office Space with Building Amenities

    Office space featuring 24/7 access and on-site management.

    1245 Jj Kelley Memorial Dr, Saint Louis, MO 63101
    View details
    Commercial Pad Site on Manchester
    Contact for pricing

    Commercial Pad Site on Manchester

    Pad site with great visibility and possible drive-thru.

    11768 Manchester Rd, Saint Louis, MO 63131
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    Renovated Office Building Near I-270
    $21 SF/Yr

    Renovated Office Building Near I-270

    Recently renovated 30,000 SF office building with ample parking.

    1715 Deer Tracks Trl, Town and Country, MO 63131
    View details
    Office Space with Open Floorplan
    Contact for pricing
    8,121 SF

    Office Space with Open Floorplan

    First floor office suite with open layout and amenities.

    660-670 Mason Rdg Ctr Dr, Town and Country, MO
    View details

    Des Peres, MO Commercial real estate Leasing Opportunities Market Analysis

    Explore Commercial real estate leasing options in Des Peres, MO with 12 listings featured on our commercial real estate exchange. The current inventory includes 2,090,880,000 square feet of properties with an estimated lease value of $20 SF/Yr.

    Estimated lease rates for Commercial real estate in Des Peres, MO begin at $20 SF/Yr, with an average of $20 SF/Yr and extend to $20 SF/Yr.
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