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    Hopkinton, MA Commercial Real Estate for Lease

    8 results
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    Hopkinton Office/Medical Space For Rent
    $19 SF/Yr
    355,885 SF

    Hopkinton Office/Medical Space For Rent

    22 South St, Hopkinton, MA 01748

    1,932 SF office/medical space available for lease.

    • Build to suit available, allowing customization.
    • Ideal location for professional or medical office.
    • 1,932 sf suite.
    • Great natural light.
    • 2nd floor accessible suite.
    Updated: Aug 15, 2025
    View details
    Hopkinton Office Space for Lease
    $19 SF/Yr
    6,720 SF

    Hopkinton Office Space for Lease

    22 South St, Hopkinton, MA 01748

    Versatile Office Suites, Prime Location

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    Hopkinton, MA Office Space
    $9 SF/Yr
    6,248 SF

    Hopkinton, MA Office Space

    Flexible Offices, Coworking & More

    35 Parkwood Dr, Hopkinton, MA 01748
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    Hopkinton Specialty Property For Rent
    $16 SF/Yr

    Hopkinton Specialty Property For Rent

    Specialty property available for rent in Hopkinton, Massachusetts.

    100-106 South St, Hopkinton, MA 01748
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    Hopkinton Warehouse with IOS Potential
    Contact for pricing
    33,040 SF

    Hopkinton Warehouse with IOS Potential

    Modern warehouse in Hopkinton, MA with highway access and IOS.

    75 South St, Hopkinton, MA 01748
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    Hopkinton Flex Space Available
    Contact for pricing
    66,024 SF

    Hopkinton Flex Space Available

    First floor flex space with 16-foot clear height.

    25 South St, Hopkinton, MA 01748
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    Hopkinton Flex/Manufacturing Space For Rent
    Contact for pricing
    11,031 SF

    Hopkinton Flex/Manufacturing Space For Rent

    Flex/manufacturing space in Hopkinton Innovation Park, easy highway access.

    107-109 South St, Hopkinton, MA 01748
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    Class A Office Building
    $27 SF/Yr
    55,000 SF

    Class A Office Building

    Class A office and lab space available in Hopkinton.

    77 Main St, Hopkinton, MA 01748
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    Based on your search, we've compiled 18 Potential Opportunities for your consideration. Besides 8 Active listings in Hopkinton, MA, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities, and Similar 6 Properties for Sales.

    Explore Commercial Real Estate for Lease in Nearby Cities

    Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

    Flex/R&D Park on Route 85
    Contact for pricing
    3,260 SF

    Flex/R&D Park on Route 85

    Two-building flex/R&D park with highway visibility and access.

    113 Cedar St, Milford, MA 01757
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    Milford Office Building For Lease
    Contact for pricing
    26,666 SF

    Milford Office Building For Lease

    Office building with 26,666 SF available for lease.

    100 Cedar St, Milford, MA 01757
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    Westborough Flex Space For Rent
    Contact for pricing
    5,000 SF

    Westborough Flex Space For Rent

    5,000 SF flex space with loading dock access.

    145 Flanders Rd, Westborough, MA 01581
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    Westborough Industrial Warehouse
    Contact for pricing
    50,000 SF

    Westborough Industrial Warehouse

    50,000 SF Build-to-Suit Opportunity

    137 Flanders Rd, Westborough, MA 01581
    View details

    Explore Similar Spaces for Sale in Hopkinton, MA

    Consider Similar Space for Sale. We found 6 Spaces in Nearby Locations matching your search parameters.

    Downtown Hopkinton Mixed-Use Development
    Contact for pricing
    75,300 SF

    Downtown Hopkinton Mixed-Use Development

    New mixed-use development with retail and residential units.

    52 Main St, Hopkinton, MA 01748
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    Modern Office Building Near Downtown
    Contact for pricing
    46,857 SF

    Modern Office Building Near Downtown

    Modern office spaces with first-class finishes and convenient location.

    34 Hayden Rowe St, Hopkinton, MA 01748
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    Hopkinton Flex Space Opportunity
    Contact for pricing
    66,024 SF

    Hopkinton Flex Space Opportunity

    Flex space available near I-495 and Mass Pike.

    45 South St, Hopkinton, MA 01748
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    Hopkinton Warehouse with Expansion Plans
    Contact for pricing
    115,970 SF

    Hopkinton Warehouse with Expansion Plans

    115,970 SF warehouse with expansion potential and heavy power.

    71 Frankland Rd, Hopkinton, MA 01748
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    Approved Medical Office Building
    $950,000

    Approved Medical Office Building

    Approved 10,000 Sq. Ft. medical office building with parking.

    28 Lumber St, Hopkinton, MA 01748
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    Hopkinton Commercial Land Opportunity
    Contact for pricing
    3.69 Acres

    Hopkinton Commercial Land Opportunity

    3.69 Acres, Prime Location, $16M

    100-106 South St, Hopkinton, MA 01748
    View details

    Hopkinton, MA Commercial Real Estate Leasing Opportunities Market Analysis

    Explore Commercial Real Estate leasing options in Hopkinton, MA with 14 listings featured on our commercial real estate exchange. The current inventory includes 18,463,044,848 square feet of properties with an estimated lease value of $74 SF/Yr.

    Estimated lease rates for Commercial Real Estate in Hopkinton, MA begin at $9 SF/Yr, with an average of $18 SF/Yr and extend to $27 SF/Yr.

    In Hopkinton, MA, current lease rates show:

    • Office Properties & Spaces positioned at $18
    • Office space measuring $18
    • Medical offices assessed at $15
    • Healthcare properties calculated at $14
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    Browse Commercial real estate for Lease Near Hopkinton, MA

    Popular Searches in Hopkinton, MA

    Most Searched ZIP Codes in Hopkinton, MA

    • 01748

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