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Hopkinton, MA Commercial Real Estate for Lease

9 results
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MA, Hopkinton - Elmwood Park
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MA, Hopkinton - Elmwood Park

Workspaces, services and support to help you work better in CA, Santa Rosa - Stony Circle

35 Parkwood Dr Lobby C, Unit 110, Hopkinton, MA 01748
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Class A Office Building
$27 SF/Yr
55,000 SF

Class A Office Building

77 Main Street, Hopkinton, MA 1748

Class A office and lab space available in Hopkinton.

  • Class A office building in downtown Hopkinton.
  • Located only 1 mile from I‑495, providing convenient highway access.
  • 3,000 - 6,070 SF of flexible office and lab space available.
  • +/-1,800 SF lab area equipped with tiled floors and an independent humidifier system.
  • Additional 815 SF office suite available with a private office and open area.
Updated: Nov 21, 2025
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Hopkinton Corporate Center Office/Lab Space
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159,795 SF

Hopkinton Corporate Center Office/Lab Space

35 Parkwood Drive, Hopkinton, MA 1748

Class A office/lab/R&D space available in Hopkinton Corporate Center.

  • Class A office/lab/R&D space available.
  • Excellent regional access via Interstate 495 and proximity to the Massachusetts Turnpike.
  • Located directly off 495.
  • Space available from ±4,155 to 12,150 SF.
  • Located in Hopkinton Corporate Center.
Updated: Jan 27
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Hopkinton Flex Space Available
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66,024 SF

Hopkinton Flex Space Available

First floor flex space with 16-foot clear height.

25 South Street, Hopkinton, MA 1748
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Hopkinton Warehouse with IOS Potential
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33,040 SF

Hopkinton Warehouse with IOS Potential

Modern warehouse in Hopkinton, MA with highway access and IOS.

75 South St, Hopkinton, MA 1748
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GMP Space Near I-495
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149,993 SF

GMP Space Near I-495

149,993 SF GMP space available for rent, can be subdivided.

52 South Street, Hopkinton, MA 1748
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Hopkinton Flex Space Opportunity
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Hopkinton Flex Space Opportunity

Modern flex space with drive-in door and potential outdoor storage.

75 South St, Hopkinton, MA 1748
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Flexible Workspace Solutions Available
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Flexible Workspace Solutions Available

Global network of workspaces with tailored office solutions.

35 Parkwood Dr,Lobby C, Suite 110, Hopkinton, MA 01748
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Hopkinton Flex/Manufacturing Space For Rent
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11,031 SF

Hopkinton Flex/Manufacturing Space For Rent

Flex/manufacturing space in Hopkinton Innovation Park, easy highway access.

107-109 South St, Hopkinton, MA
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Based on your search, we've compiled 20 Potential Opportunities for your consideration. Besides 9 Active listings in Hopkinton, MA, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities, and Similar 7 Properties for Sales.

Explore Commercial real estate for Lease in Nearby Cities

Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

Westborough Office Space Available
$17 SF/Yr
2,570 SF

Westborough Office Space Available

Professional office space for rent in a prime suburban location.

134 Flanders Road, Westborough, MA
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Westborough Flex Space For Rent
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5,000 SF

Westborough Flex Space For Rent

5,000 SF flex space with loading dock access.

145 Flanders Rd, Westborough, MA
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Milford Office Building For Lease
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26,666 SF

Milford Office Building For Lease

Office building with 26,666 SF available for lease.

100 Cedar St, Milford, MA
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Flex/R&D Park on Route 85
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3,260 SF

Flex/R&D Park on Route 85

Two-building flex/R&D park with highway visibility and access.

113 Cedar St, Milford, MA
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Explore Similar Spaces for Sale in Hopkinton, MA

Consider Similar Space for Sale. We found 7 Spaces matching your search parameters.

Modern Office Building Near Downtown
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46,857 SF

Modern Office Building Near Downtown

Modern office spaces with first-class finishes and convenient location.

34 Hayden Rowe Street, Hopkinton, MA 1748
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Hopkinton Flex Space Opportunity
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66,024 SF

Hopkinton Flex Space Opportunity

Flex space available near I-495 and Mass Pike.

45 South Street, Hopkinton, MA 1748
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Hopkinton Corner Lot Opportunity
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Hopkinton Corner Lot Opportunity

2.32 acre corner lot near Route 495.

290 West Main Street, Hopkinton, MA 1748
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Downtown Hopkinton Mixed-Use Development
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75,300 SF

Downtown Hopkinton Mixed-Use Development

New mixed-use development with retail and residential units.

52 Main Street, Hopkinton, MA 1748
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Hopkinton Warehouse with Expansion Plans
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115,970 SF

Hopkinton Warehouse with Expansion Plans

115,970 SF warehouse with expansion potential and heavy power.

71 Frankland Rd, Hopkinton, MA
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High-Visibility Corner Lot
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2.32 Acres

High-Visibility Corner Lot

Agricultural zoned land with high traffic and easy access.

52 School St, Hopkinton, MA
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Prime Land Site on Route 135
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0.75 Acres

Prime Land Site on Route 135

Desirable .75 acre land site in affluent Hopkinton, MA.

83 E Main St, Hopkinton, MA
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Hopkinton, MA Commercial real estate Leasing Opportunities Market Analysis

Explore Commercial real estate leasing options in Hopkinton, MA with 9 listings featured on our commercial real estate exchange. The current inventory includes 1,919,732,760 square feet of properties with an estimated lease value of $27 SF/Yr.

Estimated lease rates for Commercial real estate in Hopkinton, MA begin at $27 SF/Yr, with an average of $27 SF/Yr and extend to $27 SF/Yr.
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