Lewes, DE Commercial real estate for Rent & Lease

$575 / Mo

Professional Office Suite For Lease

17527 Nassau Cmns Blvd, Lewes, DE 19958

Single-room office suite in Lewes, DE, includes CAM and utilities.

Excellent location off Route 1/9 in Lewes.
CAM and utilities included in lease.
Shared conference room and break room access.
Central air conditioning.
Assigned parking in parking lot.

Updated: Jan 17

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$525 / Mo

Single-Room Office Suite in Lewes

17527 Nassau Cmns Blvd, Lewes, DE 19958

First-floor office suite with shared amenities in a prime location.

Excellent location off of Route 1 in Lewes.
CAM and utilities included in lease.
First‑floor office suite.
Shared conference room.
Shared break room.

Updated: Jan 17

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$6,000 / Mo

21,344 SF

Lewes Office Space For Lease

3,200 SF office building in desirable Nassau Commons location.

17503 Nassau Cmns Blvd, Lewes, DE 19958

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$325,000

Established Market Near Lewes Beach

Established market for sale near Lewes Beach with high traffic.

420 Savannah Rd E, Lewes, DE 19958

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$23 SF/Yr

46,609 SF

Professional Office Space For Lease

Versatile office space ideal for medical or executive use.

16529 N Coastal Hwy, Lewes, DE 19958

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$23 SF/Yr

46,609 SF

Versatile Professional Space in Lewes

Prime medical or executive office space for lease in Lewes.

16529 N Coastal Hwy, Lewes, DE 19958

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$23 SF/Yr

46,609 SF

Versatile Professional Space in Lewes

Prime medical or executive office space with customizable layout.

16529 N Coastal Hwy, Lewes, DE 19958

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$4,000 / Mo

21,344 SF

Spacious Commercial Space in Lewes

Large commercial space with parking and flexible usage options available.

17569 Nassau Cmns Blvd, Lewes, DE 19958

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$22 SF/Yr

Versatile Lewes Commercial Flex Space

Adaptable 1,962 SF space suitable for various business types.

32191 Nassau Rd, Lewes, DE 19958

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$22 SF/Yr

Lewes Office/Flex Space Available

Professional office/flex space in Lewes, DE, ideal for various businesses.

32191 Nassau Rd, Lewes, DE 19958

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$1,333 / Mo

13,000 SF

16727 Coastal Hwy

Distribution properties • 13,000 SF

16727 Coastal Hwy, Lewes, DE 19958

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$20 SF/Yr

Coastal Highway Industrial Property

Industrial properties available for rent on Coastal Highway.

18355 Coastal Hwy, Lewes, DE 19958

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$25 SF/Yr

6,340 SF

Lewes Office Building on Highway

Professional office building with direct highway frontage in Lewes, DE.

18344 Coastal Hwy, Lewes, DE 19958

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$3,000 / Mo

Route 1 Commercial Space Available

Prime commercial space on Route 1, available immediately.

18354 Coastal Hwy, Lewes, DE 19958

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$1,500 / Mo

Office Space in Nassau Commons

Office space available for lease starting October 1, 2025.

17577 Nassau Commons Blvd, Lewes, DE 19958

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$30 SF/Yr

New Retail/Office Pad Sites

Two new construction pad sites in a vibrant community.

Zinfandel Ln, Lewes, DE 19958

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Based on your search, we've compiled 169 Potential Opportunities for your consideration. Besides 16 Active listings in Lewes, DE, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities, and Similar 149 Properties for Sales.

Explore Commercial Real Estate for Lease in Nearby Cities

Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

Contact for pricing

10,125 SF

Rehoboth Beach Retail Space Available

Retail space for lease in Rehoboth Beach, Delaware.

18914 Rehoboth Mall Blvd, Rehoboth Beach, DE 19971

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$1,500 / Mo

Prime Land on Coastal Highway

Land for rent with high visibility on Route 1.

19148 Coastal Hwy, Rehoboth Beach, DE 19971

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Lewes Retail Center: Prime Space Available

$12 SF/Yr

19,412 SF

Lewes Retail Center: Prime Space Available

Multiple units, flexible lease options, ample parking.

26850 Lewes Georgetown Hwy, Harbeson, DE 19951

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$12 SF/Yr

Harbeson Industrial Space Available

Industrial space for rent in Harbeson, Delaware.

26850 Lewes Georgetown Hwy 3 #5 &, Harbeson, DE 19951

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Explore Similar Spaces for Sale in Lewes, DE

Consider Similar Space for Sale. We found 149 Spaces in Nearby Locations matching your search parameters.

$432,500

1,500 SF

Updated Condo with Private Elevator

Two-story townhouse-style condo with private elevator near Lewes and Rehoboth beaches.

18565 Orton Cir, Lewes, DE 19958

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$53,900

864 SF

Updated Mobile Home Near Beaches

Updated mobile home near beaches, restaurants, and shopping.

33873 Mcnicol Rd, Lewes, DE 19958

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$365,900

Spacious Condo Near Beach Attractions

Two-bedroom condo with community amenities and easy beach access.

17054 N Brandt St, Lewes, DE 19958

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$79,000

Move-In Ready Home in Lewes

Charming 3-bedroom home in Whispering Pines community, Lewes, DE.

31614 Dogwood Ct, Lewes, DE 19958

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$89,900

Updated Home in Sweet Briar

Well-maintained 2-bed, 1.5-bath home with modern upgrades.

17248 Pine Water Dr, Lewes, DE 19958

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$221,900

Residential Development in Historic Lewes

Residential development with affordable workforce housing in Lewes, Delaware.

2103 Emden Ln, Lewes, DE 19958

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$155,000

Park Model Tiny Home Retreat

Seasonal tiny home with marina views in West Bay.

35080 North Dr, Lewes, DE 19958

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$1,995,000

Historic Lewes Mixed-Use Building

Mixed-use building with restaurant and residential units in historic Lewes.

109 W Market St, Lewes, DE 19958

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Lewes, DE Commercial Real Estate Leasing Opportunities Market Analysis

Explore Commercial Real Estate leasing options in Lewes, DE with 165 listings featured on our commercial real estate exchange. The current inventory includes 8,792,864,716 square feet of properties with an estimated lease value of $216 SF/Yr.

Estimated lease rates for Commercial Real Estate in Lewes, DE begin at $2 SF/Yr, with an average of $30 SF/Yr and extend to $117 SF/Yr.

In Lewes, DE, current lease rates show:

Office Properties & Spaces positioned at $16
Office space measuring $17
Medical offices assessed at $23
Office buildings calculated at $14

Lewes, DE Commercial Real Estate for Lease

Professional Office Suite For Lease

Single-room office suite in Lewes, DE, includes CAM and utilities.

Single-Room Office Suite in Lewes

First-floor office suite with shared amenities in a prime location.

Lewes Office Space For Lease

Established Market Near Lewes Beach

Professional Office Space For Lease

Versatile Professional Space in Lewes

Versatile Professional Space in Lewes

Spacious Commercial Space in Lewes

Versatile Lewes Commercial Flex Space

Lewes Office/Flex Space Available

16727 Coastal Hwy

Coastal Highway Industrial Property

Lewes Office Building on Highway

Route 1 Commercial Space Available

Office Space in Nassau Commons

New Retail/Office Pad Sites

Explore Commercial Real Estate for Lease in Nearby Cities

Rehoboth Beach Retail Space Available

Prime Land on Coastal Highway

Lewes Retail Center: Prime Space Available

Harbeson Industrial Space Available

Explore Similar Spaces for Sale in Lewes, DE

Updated Condo with Private Elevator

Updated Mobile Home Near Beaches

Spacious Condo Near Beach Attractions

Move-In Ready Home in Lewes

Updated Home in Sweet Briar

Residential Development in Historic Lewes

Park Model Tiny Home Retreat

Historic Lewes Mixed-Use Building

Lewes, DE Commercial Real Estate Leasing Opportunities Market Analysis

In Lewes, DE, current lease rates show:

Browse Commercial real estate for Lease Near Lewes, DE

Popular Searches in Lewes, DE

Most Searched ZIP Codes in Lewes, DE

Lewes, DE Commercial Real Estate for Lease

Professional Office Suite For Lease

Single-room office suite in Lewes, DE, includes CAM and utilities.

Single-Room Office Suite in Lewes

First-floor office suite with shared amenities in a prime location.

Lewes Office Space For Lease

Established Market Near Lewes Beach

Professional Office Space For Lease

Versatile Professional Space in Lewes

Versatile Professional Space in Lewes

Spacious Commercial Space in Lewes

Versatile Lewes Commercial Flex Space

Lewes Office/Flex Space Available

16727 Coastal Hwy

Coastal Highway Industrial Property

Lewes Office Building on Highway

Route 1 Commercial Space Available

Office Space in Nassau Commons

New Retail/Office Pad Sites

Explore Commercial Real Estate for Lease in Nearby Cities

Rehoboth Beach Retail Space Available

Prime Land on Coastal Highway

Lewes Retail Center: Prime Space Available

Harbeson Industrial Space Available

Explore Similar Spaces for Sale in Lewes, DE

Updated Condo with Private Elevator

Updated Mobile Home Near Beaches

Spacious Condo Near Beach Attractions

Move-In Ready Home in Lewes

Updated Home in Sweet Briar

Residential Development in Historic Lewes

Park Model Tiny Home Retreat

Historic Lewes Mixed-Use Building

Lewes, DE Commercial Real Estate Leasing Opportunities Market Analysis

In Lewes, DE, current lease rates show:

Browse Commercial real estate for Lease Near Lewes, DE

Popular Searches in Lewes, DE

Most Searched ZIP Codes in Lewes, DE

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