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    Lewes, DE Commercial Real Estate for Lease

    14 results
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    Professional Office Space For Lease
    $23 SF/Yr
    46,609 SF

    Professional Office Space For Lease

    16529 N Coastal Hwy, Lewes, DE 19958

    Versatile office space ideal for medical or executive use.

    • Prime professional space ideal for medical, executive, or professional office use.
    • Versatile layout featuring multiple private offices/exam rooms, reception area, and flexible workspaces.
    • Excellent front‑facing visibility and convenient client access.
    • Strategically positioned near major healthcare destinations.
    • Opportunity to customize the layout based on operational needs.
    Updated: Jan 2
    View details
    Versatile Professional Space in Lewes
    $23 SF/Yr
    46,609 SF

    Versatile Professional Space in Lewes

    16529 N Coastal Hwy, Lewes, DE 19958

    Prime medical or executive office space for lease in Lewes.

    • Prime professional space suitable for medical or executive office use.
    • Excellent front‑facing visibility and convenient client access.
    • Versatile layout with 3 private offices/exam rooms, reception area, shared lobby, and flexible workspaces.
    • Strategically located near major healthcare destinations.
    • Opportunity to customize the layout based on operational needs.
    Updated: Jan 2
    View details
    Versatile Professional Space in Lewes
    $23 SF/Yr
    46,609 SF

    Versatile Professional Space in Lewes

    Prime medical or executive office space with customizable layout.

    16529 N Coastal Hwy, Lewes, DE 19958
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    Spacious Commercial Space in Lewes
    $4,000 / Mo
    21,344 SF

    Spacious Commercial Space in Lewes

    Large commercial space with parking and flexible usage options available.

    17569 Nassau Cmns Blvd, Lewes, DE 19958
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    Versatile Lewes Commercial Flex Space
    $22 SF/Yr

    Versatile Lewes Commercial Flex Space

    Adaptable 1,962 SF space suitable for various business types.

    32191 Nassau Rd, Lewes, DE 19958
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    Lewes Office/Flex Space Available
    $22 SF/Yr

    Lewes Office/Flex Space Available

    Professional office/flex space in Lewes, DE, ideal for various businesses.

    32191 Nassau Rd, Lewes, DE 19958
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    Established Market Near Lewes Beach
    $325,000

    Established Market Near Lewes Beach

    Established market for sale near Lewes Beach with high traffic.

    420 Savannah Rd E, Lewes, DE 19958
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    Lewes Office Space For Lease
    $6,000 / Mo
    21,344 SF

    Lewes Office Space For Lease

    3,200 SF office building in desirable Nassau Commons location.

    17503 Nassau Cmns Blvd, Lewes, DE 19958
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    16727 Coastal Hwy
    $1,333 / Mo
    13,000 SF

    16727 Coastal Hwy

    Distribution properties • 13,000 SF

    16727 Coastal Hwy, Lewes, DE 19958
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    Coastal Highway Industrial Property
    $20 SF/Yr

    Coastal Highway Industrial Property

    Industrial properties available for rent on Coastal Highway.

    18355 Coastal Hwy, Lewes, DE 19958
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    Route 1 Commercial Space Available
    $3,000 / Mo

    Route 1 Commercial Space Available

    Prime commercial space on Route 1, available immediately.

    18354 Coastal Hwy, Lewes, DE 19958
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    Lewes Office Building on Highway
    $25 SF/Yr
    6,340 SF

    Lewes Office Building on Highway

    Professional office building with direct highway frontage in Lewes, DE.

    18344 Coastal Hwy, Lewes, DE 19958
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    Office Space in Nassau Commons
    $1,500 / Mo

    Office Space in Nassau Commons

    Office space available for lease starting October 1, 2025.

    17577 Nassau Commons Blvd, Lewes, DE 19958
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    New Retail/Office Pad Sites
    $30 SF/Yr

    New Retail/Office Pad Sites

    Two new construction pad sites in a vibrant community.

    Zinfandel Ln, Lewes, DE 19958
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    Based on your search, we've compiled 168 Potential Opportunities for your consideration. Besides 14 Active listings in Lewes, DE, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities, and Similar 150 Properties for Sales.

    Explore Commercial Real Estate for Lease in Nearby Cities

    Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

    Rehoboth Beach Retail Space Available
    Contact for pricing
    10,125 SF

    Rehoboth Beach Retail Space Available

    Retail space for lease in Rehoboth Beach, Delaware.

    18914 Rehoboth Mall Blvd, Rehoboth Beach, DE 19971
    View details
    Prime Land on Coastal Highway
    $1,500 / Mo

    Prime Land on Coastal Highway

    Land for rent with high visibility on Route 1.

    19148 Coastal Hwy, Rehoboth Beach, DE 19971
    View details
    Lewes Retail Center: Prime Space Available
    $12 SF/Yr
    19,412 SF

    Lewes Retail Center: Prime Space Available

    Multiple units, flexible lease options, ample parking.

    26850 Lewes Georgetown Hwy, Harbeson, DE 19951
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    Harbeson Industrial Space Available
    $12 SF/Yr

    Harbeson Industrial Space Available

    Industrial space for rent in Harbeson, Delaware.

    26850 Lewes Georgetown Hwy 3 #5 &, Harbeson, DE 19951
    View details

    Explore Similar Spaces for Sale in Lewes, DE

    Consider Similar Space for Sale. We found 150 Spaces in Nearby Locations matching your search parameters.

    Lewes Restaurant Opportunity For Sale
    $500,000

    Lewes Restaurant Opportunity For Sale

    Turnkey restaurant in Lewes, DE with loyal following.

    17252 N Village Main Blvd, Lewes, DE 19958
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    Updated Condo with Private Elevator
    $432,500
    1,500 SF

    Updated Condo with Private Elevator

    Two-story townhouse-style condo with private elevator near Lewes and Rehoboth beaches.

    18565 Orton Cir, Lewes, DE 19958
    View details
    Updated Mobile Home Near Beaches
    $53,900
    864 SF

    Updated Mobile Home Near Beaches

    Updated mobile home near beaches, restaurants, and shopping.

    33873 Mcnicol Rd, Lewes, DE 19958
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    Spacious Condo Near Beach Attractions
    $365,900

    Spacious Condo Near Beach Attractions

    Two-bedroom condo with community amenities and easy beach access.

    17054 N Brandt St, Lewes, DE 19958
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    Move-In Ready Home in Lewes
    $79,000

    Move-In Ready Home in Lewes

    Charming 3-bedroom home in Whispering Pines community, Lewes, DE.

    31614 Dogwood Ct, Lewes, DE 19958
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    Updated Home in Sweet Briar
    $89,900

    Updated Home in Sweet Briar

    Well-maintained 2-bed, 1.5-bath home with modern upgrades.

    17248 Pine Water Dr, Lewes, DE 19958
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    Residential Development in Historic Lewes
    $221,900

    Residential Development in Historic Lewes

    Residential development with affordable workforce housing in Lewes, Delaware.

    2103 Emden Ln, Lewes, DE 19958
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    Park Model Tiny Home Retreat
    $155,000

    Park Model Tiny Home Retreat

    Seasonal tiny home with marina views in West Bay.

    35080 North Dr, Lewes, DE 19958
    View details
    Historic Lewes Mixed-Use Building
    $1,995,000

    Historic Lewes Mixed-Use Building

    Mixed-use building with restaurant and residential units in historic Lewes.

    109 W Market St, Lewes, DE 19958
    View details
    Lewes Duplex with Open Floorplan
    $839,900

    Lewes Duplex with Open Floorplan

    Custom-built Lewes duplex near attractions, shopping, dining, and beach.

    310 Burton Ave, Lewes, DE 19958
    View details

    Lewes, DE Commercial Real Estate Leasing Opportunities Market Analysis

    Explore Commercial Real Estate leasing options in Lewes, DE with 164 listings featured on our commercial real estate exchange. The current inventory includes 8,792,864,716 square feet of properties with an estimated lease value of $6,213 /Mo.

    Estimated lease rates for Commercial Real Estate in Lewes, DE begin at $2 SF/Yr, with an average of $887 /Mo and extend to $6,000 /Mo.

    In Lewes, DE, current lease rates show:

    • Office Properties & Spaces positioned at $1,016
    • Office space measuring $17
    • Medical offices assessed at $23
    • Office buildings calculated at $3,012
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    Browse Commercial real estate for Lease Near Lewes, DE

    Popular Searches in Lewes, DE

    Most Searched ZIP Codes in Lewes, DE

    • 19958

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