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    Durham, CT Commercial Real Estate for Lease

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    New Haven, CT Hartford, CT Bridgeport, CT
    16 results
    Durham Commercial Space on Main
    $1,100/Mo
    900 SF

    Durham Commercial Space on Main

    350 Main Street #Building 354, Durham, CT 6422

    Versatile 900 sq ft commercial space in Durham Center.

    • High‑traffic, central Main Street location in Durham Center offering excellent visibility.
    • Flexible 900 sq ft commercial space suitable for retail, office, studio, or creative workspace.
    • Customizable layout with optional build‑outs available.
    • Convenient access on Main Street.
    • Affordable lease at $1,100 per month plus utilities.
    Updated: Apr 22
    View details
    Downtown Durham Commercial Spaces Available
    $722/Mo

    Downtown Durham Commercial Spaces Available

    16 Main St 202, Durham, CT 6422

    Commercial spaces for rent in Downtown Durham with parking.

    • Commercial spaces available in Downtown Durham
    • Low rents
    • Plenty of parking
    • Different sizes available
    • Leases of 2 years or more preferred
    Updated: Apr 27
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    Versatile Commercial Space in Durham
    $2,500/Mo
    2,500 SF

    Versatile Commercial Space in Durham

    Flexible space in Durham Center, ideal for various businesses.

    350 Main Street, Durham, CT 6422
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    Versatile Commercial Space in Durham
    $5,000/Mo
    5,000 SF

    Versatile Commercial Space in Durham

    Flexible commercial space in central Durham, ideal for various businesses.

    350 Main Street #1, Durham, CT 6422
    View details
    Durham Commercial Space For Rent
    $975/Mo
    900 SF

    Durham Commercial Space For Rent

    900 sq ft commercial space in Durham, CT for rent.

    350 Main Street #7B, Durham, CT 6422
    View details
    Downtown Durham Retail Space Available
    $513/Mo
    1,020 SF

    Downtown Durham Retail Space Available

    Retail spaces for rent in downtown Durham with parking.

    16 Main Street #202, Durham, CT 6422
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    Versatile Commercial Space in Durham
    $2,500/Mo
    2,500 SF

    Versatile Commercial Space in Durham

    Flexible commercial space in Durham Center, ideal for various businesses.

    350 Main Street, Durham, CT 6422
    View details
    Versatile Commercial Space in Durham
    $5,000/Mo
    5,000 SF

    Versatile Commercial Space in Durham

    Flexible commercial space in Durham Center, ideal for various businesses.

    350 Main Street #1, Durham, CT 6422
    View details
    Industrial Flex Space For Rent
    $9 SF/Yr
    3,400 SF

    Industrial Flex Space For Rent

    3,400± SF industrial flex space with office and warehouse.

    42 Ozick Dr, Durham, CT
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    Industrial Flex Space For Rent
    $12 SF/Yr
    6,000 SF

    Industrial Flex Space For Rent

    2,000-6,000± SF industrial flex space available for lease.

    51 Ozick Dr, Durham, CT
    View details
    Former Bank Building Office/Retail Space
    $20 SF/Yr
    3,328 SF

    Former Bank Building Office/Retail Space

    Office/retail space in a former bank building with parking.

    376 Main St, Durham, CT
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    Retail Space on Main Street
    $12 SF/Yr
    1,350 SF

    Retail Space on Main Street

    Retail space available in Durham, Connecticut, with parking.

    370 Main St, Durham, CT
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    Former Bank Building for Lease
    Contact for pricing
    3,328 SF

    Former Bank Building for Lease

    Office/retail space in a former bank building.

    376 Main St, Durham, CT 6422
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    Retail Space Available For Rent
    Contact for pricing
    1,350 SF

    Retail Space Available For Rent

    Retail space available, approximately 1,350 square feet.

    370 Main St, Durham, CT 6422
    View details
    Based on your search, we've compiled 31 Potential Opportunities for your consideration. Besides 16 Active listings in Durham, CT, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities, and Similar 11 Properties for Sales.

    Explore Commercial real estate for Lease in Nearby Cities

    Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

    Retail/Office Space on State Route
    $17 SF/Yr
    750 SF

    Retail/Office Space on State Route

    Prime retail/office space available now on State Route 17.

    701 SOUTH MAIN St, Middletown, CT 6457
    View details
    Industrial Space Available For Rent
    $11 SF/Yr
    1,180 SF

    Industrial Space Available For Rent

    Industrial property with 1,180 square feet available for lease.

    2015 S Main St, Middletown, CT
    View details
    Middlefield Office Building For Lease
    Contact for pricing
    4,900 SF

    Middlefield Office Building For Lease

    4,900 SF single-story office building with private entrances and parking.

    8 Old Indian Trail, Middlefield, CT 6455
    View details
    Industrial Building in Middlefield, CT
    Contact for pricing
    8,394 SF

    Industrial Building in Middlefield, CT

    8,394 SF industrial building available for lease in Middlefield.

    11 Old Indian Trail, Middlefield, CT 6455
    View details

    Explore Similar Spaces for Sale in Durham, CT

    Consider Similar Space for Sale. We found 11 Spaces matching your search parameters.

    Durham Commercial Property on Route 17
    $1,300,000
    2,256 SF

    Durham Commercial Property on Route 17

    Freestanding commercial property with high visibility and renovation potential.

    980 New Haven Road, Durham, CT 06422
    View details
    Industrial Building on 2.2 Acres
    $700,000
    14,210 SF

    Industrial Building on 2.2 Acres

    14,210 SF industrial building with heavy industrial zoning.

    18 Airline Road, Durham, CT 06422
    View details
    Durham Industrial Facility on 2.14 Acres
    $660,000
    10,790 SF

    Durham Industrial Facility on 2.14 Acres

    10,790 SF industrial facility available May 1, 2025.

    19 Airline Road, Durham, CT 06422
    View details
    Industrial Building with Heavy Industrial Zoning
    $700,000
    14,210 SF

    Industrial Building with Heavy Industrial Zoning

    14,210 SF industrial building on 2.2 acres near I-91.

    18 Airline Road, Durham, CT 6422
    View details
    Large Connecticut Farm with Income
    $4,100,000
    414.50 Acres

    Large Connecticut Farm with Income

    Over 400-acre farm with multiple rental income opportunities.

    148 & 153 Wallingford Road, Durham, CT 6422
    View details
    Industrial Facility on 2.14 Acres
    $660,000
    10,790 SF

    Industrial Facility on 2.14 Acres

    10,790 SF industrial facility available May 1, 2025.

    19 Airline Road, Durham, CT 6422
    View details
    Large Durham Farm with Income Potential
    $4,100,000
    414.50 Acres

    Large Durham Farm with Income Potential

    Over 400-acre farm with multiple rental income opportunities.

    148 & 153 Wallingford Road, Durham, CT 06422
    View details
    Route 17 Commercial Property
    $1,300,000
    2,256 SF

    Route 17 Commercial Property

    Freestanding property on Route 17 with high visibility.

    980 New Haven Road, Durham, CT 6422
    View details

    Durham, CT Commercial real estate Leasing Opportunities Market Analysis

    Explore Commercial real estate leasing options in Durham, CT with 16 listings featured on our commercial real estate exchange. The current inventory includes 30,998 square feet of properties with an estimated lease value of $120 SF/Yr.

    Estimated lease rates for Commercial real estate in Durham, CT begin at $6 SF/Yr, with an average of $12 SF/Yr and extend to $20 SF/Yr.
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