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Downtown San Francisco, CA Commercial Real Estate for Lease

67 results
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CA, San Francisco - 71 Stevenson St
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CA, San Francisco - 71 Stevenson St

Workspaces, services and support to help you work better in CA, Campbell - Orchards City Dr

71 Stevenson St, San Francisco, CA 94105
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San Francisco Commercial Space Available
$8,000 /Mo
3,795 SF

San Francisco Commercial Space Available

729 Bush Street, San Francisco, CA 94108

Two-story commercial building in Lower Nob Hill for rent.

  • Prime location in Lower Nob Hill, San Francisco, near Union Square and the Financial District
  • Versatile RC‑4 zoning allows for a wide range of commercial uses
  • Rare large 3,781 sq ft lot for the area
  • Excellent transportation access via BART, cable cars, and MUNI
  • Redevelopment potential, including vertical expansion and modern medical build‑outs
Updated: Aug 1, 2025
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CA, San Francisco - 101 Montgomery
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CA, San Francisco - 101 Montgomery

101 Montgomery St, Unit 900, San Francisco, CA 94111

Workspaces, services and support to help you grow your business in CA, San Francisco - 101 Montgomery

  • Make a home for yourself and your team in a private office, fully serviced and flexible, with everything included
  • Grow in a modern workplace with the added advantage of a benefits program offering exclusive discounts and bespoke procurement support
  • Find your own private desk in a beautifully designed shared workspace with 24/7 access, a personal locker, and an inviting reception team
  • Virtual offices allow you to establish a presence at any Spaces location worldwide with mail handling, a virtual call assistant, and on‑demand access
  • Spaces' meeting rooms have everything you need from audiovisual equipment, whiteboards, and Wi‑Fi to food and beverage services
Updated: Feb 19
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Spaces Levi's Plaza
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Spaces Levi's Plaza

Find fully flexible work and meeting space in Spaces Levi's Plaza

1160 Battery St, San Francisco, CA 94111
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California Street
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California Street

Discover many ways to work your way in California Street

50 California St, Unit 1500, San Francisco, CA 94111
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Jackson Square Office Space Available
$85 SF/Yr
5,400 SF

Jackson Square Office Space Available

Sublease opportunity in Jackson Square with creative finishes.

402 Jackson St, San Francisco, CA 94111
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Prime Jackson Square Office Space
$39 SF/Yr
22,716 SF

Prime Jackson Square Office Space

Classic brick and timber building in Jackson Square, San Francisco.

414 Jackson Street, San Francisco, CA 94111
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CA, San Francisco - 580 California
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CA, San Francisco - 580 California

Discover many ways to work your way in CA, San Francisco - 580 California

580 Floors, San Francisco, CA 94104
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Creative Office Space in San Francisco
$79 SF/Yr
29,536 SF

Creative Office Space in San Francisco

Creative office suite with views of Union Square available for rent.

240 Stockton Street, San Francisco, CA 94108
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505 Montgomery
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505 Montgomery

All-inclusive access to workspace, virtual office and meeting rooms in 505 Montgomery

505 Floors, San Francisco, CA 94111
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Market Street Office Space Available
$2.00 SF/Yr
103,000 SF

Market Street Office Space Available

Plug and play office spaces for immediate occupancy on Market.

995 Market, San Francisco, CA 94111
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Class A Office Tower
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103,079 SF

Class A Office Tower

Mixed-use office tower in San Francisco's North Financial District.

655 Montgomery Street, San Francisco, CA 94111
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Distinctive High-Rise Office Space
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386,965 SF

Distinctive High-Rise Office Space

Centrally located office building in San Francisco's South Financial District.

55 2nd Street, San Francisco, CA 94105
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Creative Office Space Near BART
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Creative Office Space Near BART

Creative office space with new finishes and excellent natural light.

20 California Street, San Francisco, CA 94111
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Fremont Street Office Space Available
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19,628 SF

Fremont Street Office Space Available

Office space for rent through July 2024.

50 Fremont Street, San Francisco, CA 94105
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Class A Office Space
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Class A Office Space

Class A office building in desirable waterfront location.

150 Spear Street, San Francisco, CA 94105
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Full Floor Office Space
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17,948 SF

Full Floor Office Space

Available now: 17,948 RSF full floor office space.

1 Market Street, San Francisco, CA 94105
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Adaptable Space in Prime Location
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29,349 SF

Adaptable Space in Prime Location

29,349 sq ft building offering accessible location and signage.

900 Sansome Street, San Francisco, CA 94111
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Retail Space in San Francisco
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1,080 SF

Retail Space in San Francisco

Retail space available for lease in San Francisco, CA.

50 California Street, San Francisco, CA 94111
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Restaurant Space on Mission Street
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2,730 SF

Restaurant Space on Mission Street

Second generation restaurant space with frontage on Mission Street.

88 1st Street, San Francisco, CA 94105
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Retail Space in Class A Building
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3,168 SF

Retail Space in Class A Building

Retail space available in a Class A office building.

201 Spear Street, San Francisco, CA 94105
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Class A Office Space
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83,551 SF

Class A Office Space

Modern office space in the South Financial District.

505 Howard Street, San Francisco, CA 94105
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Revitalized Retail Space in San Francisco
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Revitalized Retail Space in San Francisco

Mixed-use waterfront neighborhood retail space for lease in San Francisco.

460 Davis Ct, San Francisco, CA 94111
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Lower-Level Office Space Available
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6,000 SF

Lower-Level Office Space Available

6,000 RSF office space with rooftop deck access.

30 Hotaling Pl, San Francisco, CA 94111
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Downtown San Francisco, CA Commercial real estate Leasing Opportunities Market Analysis

Explore Commercial real estate leasing options in Downtown San Francisco, CA with 67 listings featured on our commercial real estate exchange. The current inventory includes 15,997,889,160 square feet of properties with an estimated lease value of $1,802 /Mo.

Estimated lease rates for Commercial real estate in Downtown San Francisco, CA begin at $1.00 SF/Yr, with an average of $25 SF/Yr and extend to $131 SF/Yr.
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