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    La Jolla, CA Commercial Real Estate for Lease

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    Found 1,026 commercial real estate listings for lease in La Jolla, CA, averaging $22/SF/YR. Use lease type data to compare options faster.
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    Law Firm Office Suite
    Law Firm Office Suite

    600 B St, San Diego, CA 92101

    Core-Columbia
    Contact for pricing
    5–8 people  1,273 sqft
    3 private offices  1 meeting room

    Contiguous office suites with reception, three private offices, a conference room, and break area.

    Reception  Break area
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    ESFR-Sprinklered Warehouse
    ESFR-Sprinklered Warehouse

    1462 Corporate Center Drive, San Diego, CA 92154

    Triple net (NNN) Ocean Crest
    Contact for pricing
    41,780 sqft  28 ft clear  7 docks  Heavy power

    Multi-tenant warehouse featuring 28-foot clear height, ESFR sprinklers, and dock loading with office space.

    Sprinklered
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    Experiential Retail Space in San Diego
    Experiential Retail Space in San Diego

    655 W Broadway, San Diego, CA 92101

    Full service Core-Columbia
    Contact for pricing
    2,327 sqft

    High-rise retail space in downtown San Diego's vibrant core.

    View details
    Class A Office Building with Conference Center
    Class A Office Building with Conference Center

    750 B St, San Diego, CA 92101

    Full service Class A Core-Columbia
    Contact for pricing
    22–37 people  1 space  5,634 sqft  34-story

    Downtown San Diego Class A high-rise with a 12th-floor sky conference center and tenant amenities including EV charging and 24/7 security.

    Valet parking  EV charging stations  24/7 security  Sky Conference Center
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    Class A High-Rise Office Building
    Class A High-Rise Office Building

    750 B St, San Diego, CA 92101

    Full service Class A Core-Columbia
    Contact for pricing
    8–14 people  1 space  2,206 sqft  34-story

    Class A office tower with floor-to-ceiling windows, EV charging, 24/7 security, and a 32-person conference center.

    Valet parking  EV charging stations  24/7 security  Sky Conference Center
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    Serviced Office Suite in Downtown Tower
    Serviced Office Suite in Downtown Tower

    501 W. Broadway, San Diego, CA 92101

    Coworking Gaslamp
    Contact for pricing
    396–660 people  99,113 sqft  Built 2026  21-story

    Serviced office suite with arched entry, atrium lobby, and marble finishes in a 21-story downtown high-rise.

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    Retail Inline Shop Space
    Retail Inline Shop Space

    7092 Miramar Road, San Diego, CA 92121

    Miramar
    Contact for pricing
    1,080 sqft
    56,746 VPD  Highway access

    Inline shop space available with easy access via four points of ingress/egress at a signalized intersection.

    View details
    Freestanding Restaurant with Patio
    Freestanding Restaurant with Patio

    2901 5th Ave, San Diego, CA 92103

    Park West
    Contact for pricing
    3,325 sqft

    Marquee freestanding restaurant space with an outdoor patio, totaling about 3,325 SF.

    Wellness spa  Private park  Rooftop pool and spa  Coworking hub
    View details
    Office Units with Private Offices
    Office Units with Private Offices

    3323 Carmel Mountain Rd, San Diego, CA 92121

    Torrey Preserve
    Contact for pricing
    13–21 people  3,250 sqft

    Office units with open office and private offices, plus restroom and utility/stairwell; available Feb 1, 2027.

    View details
    Office Suite with Built-In Amenities
    Office Suite with Built-In Amenities

    7676 Hazard Center Dr, San Diego, CA 92108

    Full service Mission Valley East
    Contact for pricing
    10–16 people  1 space  2,533 sqft

    Office suite offering 24-hour access, conferencing facilities, and on-site convenience retail and fitness options.

    24 Hour Access  Bus Line  Conferencing Facility  Convenience Store
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    Renovated Retail Space
    Renovated Retail Space

    6818-6822 El Cajon Blvd, San Diego, CA 92115

    Gross College East
    Contact for pricing
    1,000 sqft

    Updated commercial space with existing plumbing and a private restroom for retail operations.

    Plumbing in place  In-suite restroom
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    Second-Floor Creative Event Space
    Second-Floor Creative Event Space

    3451-3465 El Cajon Blvd, San Diego, CA 92104

    Gross Corridor
    Contact for pricing
    19–32 people  1 space  4,909 sqft

    Recently renovated creative office and event space on the second floor with 20-foot ceilings.

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    Anchored Retail Center Space
    Anchored Retail Center Space

    1652-1750 Camino Del Rio N, San Diego, CA 92108

    Mission Valley East
    Contact for pricing
    1,955 sqft

    Retail space available within a center anchored by Target, AMC, Nordstrom Rack, Michael’s, and Bloomingdale Outlet.

    View details
    Science District Office and Lab Campus
    Science District Office and Lab Campus

    10581 Roselle St., San Diego, CA 92121

    Sorrento Valley
    Contact for pricing
    22–36 people  5,528 sqft  Multi-tenant

    Four clustered campus provides flexible office and lab space within a life sciences science district.

    The Craft Taco  New English Brewing  The Coffee Cart  Conferencing & Event Spaces
    View details
    Secured Industrial Land
    Secured Industrial Land

    4174-4206 Sorrento Valley Blvd, San Diego, CA 92121

    Sorrento Valley
    Contact for pricing
    5.6 acres

    Fenced industrial land offers utility availability, multiple curb cuts, and permitted equipment and materials storage.

    View details
    Second-Generation Wine/Beer Bar Opportunity
    Second-Generation Wine/Beer Bar Opportunity

    2130 India St, San Diego, CA 92101

    Gross Little Italy
    Contact for pricing
    2,320 sqft

    For lease second-generation restaurant space with a wine or beer-bar concept in San Diego’s North Little Italy.

    View details
    Standalone Flex Creative R&D Building
    Standalone Flex Creative R&D Building

    9800 Campus Point Dr, San Diego, CA 92121

    Sorrento Valley
    Contact for pricing
    96,500 sqft

    Standalone flex/creative/R&D building offers a mix of office and flex/industrial space with secure, controlled-access campus setting.

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    Flexible Office and Lab Space
    Flexible Office and Lab Space

    11555 Sorrento Valley Rd, San Diego, CA 92121

    Torrey Pines
    Contact for pricing
    14–24 people  3,740 sqft

    Office units within the SOVA Science District campus with conferencing, outdoor collaboration areas, and fitness amenities.

    View details
    Office Suite with Conference Room
    Office Suite with Conference Room

    600 B St, San Diego, CA 92101

    Core-Columbia
    Contact for pricing
    7–11 people  1,790 sqft
    3 private offices  1 meeting room

    Suite includes three private window-lined offices and a conference room.

    View details
    La Jolla Executive Office Space
    La Jolla Executive Office Space

    4225 Executive Sq, La Jolla, CA 92037

    Contact for pricing
    17–28 people  4,343 sqft

    Executive office space available for lease in La Jolla, CA.

    View details
    Medical Office Space with 24/7 Access
    Medical Office Space with 24/7 Access

    2131 3rd Ave, San Diego, CA 92101

    Park West
    Contact for pricing
    1,905 sqft

    Medical office suite in a new development featuring 24/7 controlled access and advanced security.

    View details
    Retail Space in Adams Avenue
    Retail Space in Adams Avenue

    2911 Adams Avenue, San Diego, CA 92116

    Mission Valley East
    Contact for pricing
    1,346 sqft

    Established retail district with high foot traffic and neighborhood charm.

    View details
    Office Building for Lease
    Office Building for Lease

    4909 Murphy Canyon Rd, San Diego, CA 92123

    Kearny Mesa
    Contact for pricing
    20–33 people  1 space  5,000 sqft

    Office building available for lease at 4909 Murphy Canyon Rd in San Diego.

    View details
    Retail Storefront Space
    Retail Storefront Space

    3425 Murphy Canyon Road, San Diego, CA 92123

    Serra Mesa
    Contact for pricing
    7,200 sqft
    Highway access

    Retail storefront space in a high-traffic area adjacent to I-15 with strong co-tenancy.

    View details
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