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    La Jolla, CA Commercial Real Estate for Lease

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    Found 1,026 commercial real estate listings for lease in La Jolla, CA, averaging $22/SF/YR. Use lease type data to compare options faster.
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    Renovated San Diego Amenity-Rich Space
    Renovated San Diego Amenity-Rich Space

    8145-8245 Ronson Rd., San Diego, CA 92111

    Coworking Kearny Mesa
    Contact for pricing
    3 spaces  Built 2026

    Recently renovated office and fitness spaces with extensive amenity center.

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    Renovated Office Building For Lease
    Renovated Office Building For Lease

    9320 Chesapeake Dr, San Diego, CA

    Kearny Mesa
    Contact for pricing
    5–9 people  2 spaces  1,472 sqft  1.11 acres

    Recently renovated office building with central San Diego location.

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    Brewery Site with Tasting Room
    Brewery Site with Tasting Room

    701 Island Ave, San Diego, CA

    East Village
    Contact for pricing
    3,533 sqft

    Second-generation brewery with tasting room near Petco Park.

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    Retail Space in San Diego
    Retail Space in San Diego

    8657 Villa La Jolla Drive, San Diego, CA 92037

    La Jolla
    Contact for pricing

    Retail property available for lease in San Diego, California.

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    Creative Office Suite with Conference Room
    Creative Office Suite with Conference Room

    2251 San Diego Ave, San Diego, CA 92110

    Full service Old Town
    Contact for pricing
    1 person  1 space  293 sqft  modern Spanish style
    Highway access

    Renovated office suite featuring six private offices and a conference room with exposed wood beams and vaulted ceilings.

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    Retail Space on West Broadway
    Retail Space on West Broadway

    725 West Broadway, San Diego, CA 92101

    Core-Columbia
    Contact for pricing

    Retail property available for lease on West Broadway.

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    Office Building Converted to Lab
    Office Building Converted to Lab

    10201 Wateridge Cir, San Diego, CA 92121

    Sorrento Valley
    Contact for pricing
    77–128 people  19,273 sqft

    Office building now available for lease, converted to lab use in Q2 2023.

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    ABC-Licensed Nightclub and Office
    ABC-Licensed Nightclub and Office

    500-502 Fourth Ave, San Diego, CA 92101

    Triple net (NNN) Marina
    Contact for pricing
    11,000 sqft  2-story

    Includes an ABC-licensed 11,000 SF nightclub plus 2,000 SF second-floor office.

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    Retail Space on El Cajon
    Retail Space on El Cajon

    3052 El Cajon Boulevard, San Diego, CA 92104

    North Park
    Contact for pricing

    Retail property available for lease on El Cajon Boulevard.

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    Office Building Converted to Lab Space
    Office Building Converted to Lab Space

    10201 Wateridge Cir, San Diego, CA 92121

    Sorrento Valley
    Contact for pricing
    81–136 people  20,482 sqft

    Office building now available for lease, converted to lab space, offering a flexible suite size range.

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    Move-In Ready Office Suites Available
    Move-In Ready Office Suites Available

    8755-8775 Aero Dr, San Diego, CA

    Modified gross Serra Mesa
    Contact for pricing
    9–16 people  2 spaces  2,496 sqft  3.93 acres

    Office suites available for rent with flexible lease terms.

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    Office Building with EV Parking
    Office Building with EV Parking

    550 W C St, San Diego, CA 92101

    Core-Columbia
    Contact for pricing
    75–125 people  18,872 sqft

    Office building with enhanced lobby, fully equipped conference room, gym, and EV-charging parking for tenants.

    Enhanced lobby  Dining and outdoor amenities  EV charging stations  Panoramic views
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    Office Space with Exterior Patios
    Office Space with Exterior Patios

    6160 Cornerstone Ct E, San Diego, CA 92121

    Sorrento Valley
    Contact for pricing
    67–113 people  1 space  16,956 sqft
    Highway access

    Office space features operable windows, exterior patios, and in-building Wi-Fi with convenient on-site parking options.

    3.8/1,000 SF parking  Wi-Fi in common area courtyard  Exterior patios  Operable windows
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    Multi-Tenant Industrial Warehouse
    Multi-Tenant Industrial Warehouse

    7949 Stromesa Ct, San Diego, CA 92126

    Miramar
    Contact for pricing
    9,400 sqft  22 ft clear  Multi-tenant
    Highway access  IL- 2-1

    Multi-tenant industrial building with 22' warehouse clear height, skylights, and fully sprinklered spaces.

    Sprinklered
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    Office Space For Lease
    Office Space For Lease

    17190 Bernardo Center Dr, San Diego, CA 92128

    Rancho Bernardo
    Contact for pricing
    10–18 people  2,707 sqft

    Office space is available for lease at 17190 Bernardo Center Dr, with suites ranging in size.

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    Office Building with Bay Views
    Office Building with Bay Views

    550 W C St, San Diego, CA 92101

    Core-Columbia
    Contact for pricing
    9–16 people  2,488 sqft
    Public transit

    Office building with panoramic San Diego Bay views, EV-charging parking, gym, and a fully equipped conference room.

    2.0/1,000 SF parking  Enhanced lobby  Dining  Outdoor amenities
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    Office Space in Secure Location
    Office Space in Secure Location

    16705 Via Del Campo Ct, San Diego, CA

    Rancho Bernardo
    Contact for pricing
    113–188 people  28,313 sqft  11.72 acres

    Office space with high-quality construction and lab-ready features.

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    Retail Space in Torrey Hills
    Retail Space in Torrey Hills

    4627-4645 Carmel Mountain Rd, San Diego, CA 92130

    Carmel Valley
    Contact for pricing
    2,172 sqft

    Retail space available in a contemporary California Craftsman style center.

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    San Diego Warehouse Space Available
    San Diego Warehouse Space Available

    5 Via De la Amistad, San Diego, CA 92154

    Otay Mesa
    Contact for pricing
    Built 2026

    Warehouse space available for rent in San Diego, California.

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    Creative Office Space with Balconies
    Creative Office Space with Balconies

    185 W F St, San Diego, CA 92101

    Full service Horton Plaza
    Contact for pricing
    4–8 people  1 space  1,207 sqft

    Renovated building offers 9,000 SF floor plates and direct subterranean parking access into a lobby.

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    Contiguous Office Suites
    Contiguous Office Suites

    600 B St, San Diego, CA 92101

    Core-Columbia
    Contact for pricing
    5–9 people  1,446 sqft

    Contiguous office suites with double-door entry off the elevator lobby.

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    Office Building with Vaulted Lobby
    Office Building with Vaulted Lobby

    16745 W Bernardo Dr, San Diego, CA 92127

    Rancho Bernardo
    Contact for pricing
    13–21 people  3,267 sqft
    Public transit

    Office building with panoramic views, vaulted lobby, and on-site showers and locker facilities.

    Signage opportunities  Panoramic views  Future development opportunities  Showers and locker facilities
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    Industrial Land
    Industrial Land

    10065 Via De La Amistad, San Diego, CA 92154

    Otay Mesa
    Contact for pricing
    0.54 acres

    Available for a flexible one-year sublease term.

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    Life Science Flex Office Lab Space
    Life Science Flex Office Lab Space

    10431 Wateridge Cir, San Diego, CA 92121

    Sorrento Valley
    Contact for pricing
    15,075 sqft
    Highway access

    Two-building campus offers office and lab buildout, including benches, freezer rooms, and lab support with office workstation areas.

    Two-story lobbies  Elevator service  Conference room  Break area
    View details
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