Charleston, MO Retail properties & Spaces for sale

Updated: Apr 10, 2025

Retail Building with Highway Frontage

1113 E. Marshall, Charleston, MO 63834

$99,900

2,121 sqft

2,121‑square‑foot existing building constructed in 1947
More than 300 feet of highway frontage
Approximately 1 mile from I‑57
Property encompasses more than 2 acres
Commercial zoning

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Updated: Oct 4, 2024

Office Building with Open Floor Space

2380 S. Main, Charleston, MO 63834

$79,000

1,452 sqft 0.73 AC lot

1,452 square feet of building area on 0.73 acres
Two offices plus approximately 1,000 square feet of open floor space
Additional rear area for offices or work space
Commercial zoning along Hwy 105
Forced‑air heating and central air conditioning

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Realmo Analytics Monitor Off-market properties and contact owners who are ready to sell. Many signals applied to make quality leads for you. Get Leads

Based on your search, we've compiled 80 Potential Opportunities for your consideration. Besides 2 Active listings in Charleston, MO, we suggest exploring several alternatives: 4 properties in Nearby Cities, and similar 70 Off-Market properties to explore as potential leads, plus 4 Land Listings that present a potential for development.

Opportunities in Nearby Cities

Here are 4 Similar properties we found in Nearby Locations for your consideration.

Historic Two-Story Storefront

124 E Front Street, Sikeston, MO 63801

$275,000

14,642 sqft 0.22 AC lot

Brick commercial building with leased ground-floor space and an open upper level.

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Retail Space with Fenced Courtyard

3101-3103 Sycamore St, Cairo, IL 62914

$199,000

40,000 sqft

Flexible commercial layout with customer parking and retained mechanical systems.

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Historic Two-Story Storefront

112 Front Street, Sikeston, MO 63801

$190,000

0.11 AC lot

Brick construction, public water, and central air serve this downtown commercial property.

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Storefront Property with Fenced Courtyard

3101-3103 Sycamore Street, Cairo, IL 62914

$199,000

0.16 AC lot

The building includes customer parking, retained mechanical systems, and a flexible interior arrangement.

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Potential Development Sites for Consideration

Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

Commercial Land with Highway Frontage

103 Grove Estates, Sikeston, MO 63801

$144,000

1.01 AC lot

C-1 zoning and public utilities support neighborhood-serving retail, office, medical, and professional uses.

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Corner Industrial Land

414 Elm St, Cape Girardeau, MO 63703

Contact for pricing

0.34 AC lot

Corner double lot with public water, public sewer, and cable availability.

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Commercial Land Adjacent to Casino

N Main Street, Cape Girardeau, MO 63701

$450,000

1.04 AC lot

Commercially zoned site with public water and sewer service available in Cape Girardeau.

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Renovated Office Building

230 N Sprigg Street, Cape Girardeau, MO 63701

$239,900

2,937 sqft 0.25 AC lot

Brick commercial property with central air, public utilities, and open-lot parking near downtown activity.

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Off-Market Properties in Charleston, MO

Consider similar Off-Market properties in Charleston, MO. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.