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Saco, ME Office Units for Lease

6 results
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Saco Medical Office Suite
$13 SF/Yr
10,000 SF

Saco Medical Office Suite

655 Main St, Saco, ME

10,000± SF medical office suite for rent.

  • 10,000± SF medical office suite
  • Located just off I‑195 and Route One
  • Convenient to downtown Saco
  • Highly visible location
  • Second floor suite
Updated: Oct 6, 2025
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Downtown Saco Office Space Available
$18 SF/Yr
1,772 SF

Downtown Saco Office Space Available

209 Main Street, Saco, ME

Office/studio space for rent in downtown Saco.

  • Prime downtown Saco location
  • On‑site parking available
  • 1,222± SF of 3rd floor office/studio space
  • Steps away from the Amtrak Downeaster
  • Easy access to I‑95
Updated: May 6, 2025
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Saco Flex Space For Lease
$13 SF/Yr
4,590 SF

Saco Flex Space For Lease

Flex space suitable for office or medical office use.

42 Industrial Park Rd, Saco, ME 4072
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Retail/Athletic Space in Saco
Contact for pricing

Retail/Athletic Space in Saco

Retail/athletic space in OA Sports Center complex, accessible from I-195.

15 Lund Rd, Saco, ME 4072
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Prime Retail Building on Corner
Contact for pricing

Prime Retail Building on Corner

Stand-alone retail building for lease in Saco's commercial corridor.

70 Elm St, Saco, ME 4072
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Saco Flex Space Available
Contact for pricing
4,590 SF

Saco Flex Space Available

Flex space suitable for office or medical office use.

42 Industrial Park Rd, Saco, ME 4072
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Based on your search, we've compiled 15 Potential Opportunities for your consideration. Besides 6 Active listings in Saco, ME, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities, and Similar 1 Properties for Sales.

Explore Office Units for Lease in Nearby Cities

Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

Scarborough Medical/Office Space For Lease
$13 SF/Yr
1,049 SF

Scarborough Medical/Office Space For Lease

Class A office suites for lease in Scarborough, Maine.

51 US Route 1, Scarborough, ME 4074
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Historic Mill Campus Commercial Space
$20 SF/Yr
630 SF

Historic Mill Campus Commercial Space

Revitalized mill campus offering flexible commercial suites for lease.

2 Main St Ste 37-101, Biddeford, ME
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Downtown Biddeford Class A Office
$28 SF/Yr
64,800 SF

Downtown Biddeford Class A Office

New Class A office space in Biddeford, available Spring 2025.

3 Lincoln Street, Biddeford, ME 4005
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Prime Retail/Office Space Available
$1.00 SF/Yr

Prime Retail/Office Space Available

Build-to-suit suites on US Route 1 in Scarborough.

707 US-1, Scarborough, ME 04074
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Explore Similar Spaces for Sale in Saco, ME

Consider Similar Space for Sale. We found 1 Spaces matching your search parameters.

Saco Commercial Building For Sale
$2,900,000
10,260 SF

Saco Commercial Building For Sale

Commercial building in Saco, Maine, suitable for multiple uses.

5 Willey Road, Saco, ME 04072
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Potential Development Sites for Consideration

Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

Saco Gas/Convenient Store Site
Contact for pricing

Saco Gas/Convenient Store Site

Prime development site on Main Street in Saco, Maine.

650 Main Street, Saco, ME 4072
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8 Acres Build-to-Suit Land
Contact for pricing

8 Acres Build-to-Suit Land

8+/- acre land parcel available for lease or build-to-suit.

991 Portland Rd, Saco, ME
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Retail Development or Ground Lease
Contact for pricing
16,000 SF

Retail Development or Ground Lease

Retail development or ground lease opportunity up to 16,000 SF.

574 Alfred Rd, Biddeford, ME 4005
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Arundel Business Park Land Opportunity
Contact for pricing

Arundel Business Park Land Opportunity

Land for sale in thriving business park off Route One.

Enterprise Dr, Arundel, ME
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Saco, ME Office Units Leasing Opportunities Market Analysis

Explore Office Units leasing options in Saco, ME with 6 listings featured on our commercial real estate exchange. The current inventory includes 435,600,000 square feet of properties with an estimated lease value of $13 SF/Yr.

Estimated lease rates for Office Units in Saco, ME begin at $13 SF/Yr, with an average of $13 SF/Yr and extend to $13 SF/Yr.
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