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San Francisco, CA Office Units for Lease

436 results
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San Francisco Commercial Space Available
$8,000 / Mo
3,795 SF

San Francisco Commercial Space Available

729 Bush St, San Francisco, CA 94108

Two-story commercial building in Lower Nob Hill for rent.

  • Prime location in Lower Nob Hill, San Francisco, near Union Square and the Financial District
  • Versatile RC‑4 zoning allows for a wide range of commercial uses
  • Rare large 3,781 sq ft lot for the area
  • Excellent transportation access via BART, cable cars, and MUNI
  • Redevelopment potential, including vertical expansion and modern medical build‑outs
Updated: Dec 30, 2025
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Move-in Ready Office Space Available
$15 SF/Yr
10,800 SF

Move-in Ready Office Space Available

1338 Mission St, San Francisco, CA 94103

Three floors of office space in a convenient San Francisco location.

  • Move‑in ready office space across three floors.
  • Convenient Western SoMa location near Civic Center and City Hall.
  • Easy access to public transportation (BART/Muni 1 block away).
  • Each floor has a private restroom and full HVAC.
  • Elevator and stair access to all floors.
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Creative Space in SOMA District
$22 SF/Yr
62,000 SF

Creative Space in SOMA District

Unique creative space in a prime SOMA location for rent.

972 Mission St, San Francisco, CA 94103
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Versatile Office Space in San Francisco
$45 SF/Yr
16,900 SF

Versatile Office Space in San Francisco

Varied office solutions in a convenient Financial District location.

665 Chestnut St, San Francisco, CA 94133
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Modern Space in SoMa District
Contact for pricing

Modern Space in SoMa District

Contemporary property ideal for retail, office, or showroom use.

1222 Harrison St, San Francisco, CA 94103
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Historic Mixed-Use Complex on Van Ness
$0.74 SF/Yr
164,168 SF

Historic Mixed-Use Complex on Van Ness

Modern mixed-use complex with retail, office, and entertainment spaces.

1000 Van Ness Ave, San Francisco, CA 94109
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Modern Office in Financial District
Contact for pricing

Modern Office in Financial District

Class-A high-rise with on-site amenities and easy transit access.

100 1St St, San Francisco, CA 94105
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1st Floor Office Space
$3 SF/Yr
1,400 SF

1st Floor Office Space

1,400 SF office space with four private offices.

3626 Sacramento St, San Francisco, CA 94118
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Hayes Valley Victorian Office Space
$42 SF/Yr
1,750 SF

Hayes Valley Victorian Office Space

Move-in ready office in a beautiful Victorian building.

257 Oak St, San Francisco, CA 94102
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Full Floor Office Space Available
$32 SF/Yr
2,900 SF

Full Floor Office Space Available

Full floor office space with excellent natural light.

3500-3502 Geary Blvd, San Francisco, CA 94118
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Full Floor Medical Office Space
$1.50 SF/Yr
4,367 SF

Full Floor Medical Office Space

Full floor medical suite with exam and private offices.

1833 Fillmore St, San Francisco, CA 94115
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Renovated North Beach Office Space
$45 SF/Yr
1,495 SF

Renovated North Beach Office Space

Office space in one of the nation's best neighborhoods.

256 Columbus Ave, San Francisco, CA 94133
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Divisadero Street Office Space
$4,700 / Mo
1,350 SF

Divisadero Street Office Space

Office space with great natural light and private offices.

2057 Divisadero St, San Francisco, CA 94115
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Hayes Valley Office Space
$48 SF/Yr
1,800 SF

Hayes Valley Office Space

Office space in Hayes Valley with high ceilings and views.

44 Page St, San Francisco, CA 94102
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Full Floor Office Space
$45 SF/Yr
1,600 SF

Full Floor Office Space

Full floor office space in the South Financial District.

163 2Nd St, San Francisco, CA 94105
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Creative Office Space Available
$47 SF/Yr
2,341 SF

Creative Office Space Available

Creative open office space with hardwood floors and operable windows.

49 Geary St, San Francisco, CA 94108
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Full Floor Office Space
$42 SF/Yr
2,401 SF

Full Floor Office Space

Furnished full floor office space with natural light.

1841 Market St, San Francisco, CA 94103
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Office Space in American Industrial Center
$2 SF/Yr
4,000 SF

Office Space in American Industrial Center

4,000 SF office space available for sublease.

2415 3Rd St, San Francisco, CA 94107
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Jackson Square Office Space Available
$36 SF/Yr
2,219 SF

Jackson Square Office Space Available

Corner office space with views in vibrant Jackson Square.

850-888 Montgomery St, San Francisco, CA 94133
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Move-in Ready Office Space Available
$15 SF/Yr
2,897 SF

Move-in Ready Office Space Available

Three floors of office space for rent in San Francisco.

1338 Mission St, San Francisco, CA 94103
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Market Street Office Space Available
$19 SF/Yr
947 SF

Market Street Office Space Available

Office space for lease in San Francisco, CA.

1212 Market St, San Francisco, CA 94102
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Modern Office Space Available
$2 SF/Yr
5,000 SF

Modern Office Space Available

5,000 SF office space with high ceilings and natural light.

1261-1263 Howard St, San Francisco, CA 94103
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Full Floor Office Suite ForRent
$2 SF/Yr
7,210 SF

Full Floor Office Suite ForRent

Full floor office suite with city views available for rent.

2601 Mission St, San Francisco, CA 94110
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Corner Office Suite with Amenities
$3,500 / Mo
1,737 SF

Corner Office Suite with Amenities

Office space featuring natural light, kitchen, and private bathroom.

220-222 Columbus Ave, San Francisco, CA 94133
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San Francisco, CA Office Units Leasing Opportunities Market Analysis

Explore Office Units leasing options in San Francisco, CA with 507 listings featured on our commercial real estate exchange. The current inventory includes 106,029,003,960 square feet of properties with an estimated lease value of $2,625 /Mo.

Estimated lease rates for Office Units in San Francisco, CA begin at $0.74 SF/Yr, with an average of $32 SF/Yr and extend to $100 SF/Yr.
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