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San Francisco, CA Office Space for Lease

481 results
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San Francisco Commercial Space Available
$8,000 / Mo
3,795 SF

San Francisco Commercial Space Available

729 Bush St, San Francisco, CA 94108

Two-story commercial building in Lower Nob Hill for rent.

  • Prime location in Lower Nob Hill, San Francisco, near Union Square and the Financial District
  • Versatile RC‑4 zoning allows for a wide range of commercial uses
  • Rare large 3,781 sq ft lot for the area
  • Excellent transportation access via BART, cable cars, and MUNI
  • Redevelopment potential, including vertical expansion and modern medical build‑outs
Updated: Dec 30, 2025
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Renovated Retail/Office Space in Mission
$2,500 / Mo
555 SF

Renovated Retail/Office Space in Mission

Mission St, San Francisco, CA 94110

Newly renovated 700 SF retail/office space in vibrant Mission District.

  • Prime Location: Situated in the heart of San Francisco's high‑traffic Mission District.
  • Move‑In Ready: Newly renovated and in the final stages of construction, ensuring a seamless transition.
  • Flexible Space: Suitable for creative professionals, boutique retail, or office use.
  • Includes a dedicated private restroom.
  • High Visibility: Offers excellent exposure in a desirable commercial corridor.
Updated: May 28, 2025
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San Francisco Retail/Office Space
$1,875 / Mo
800 SF

San Francisco Retail/Office Space

800 sqft retail or office space for lease.

Holloway Ave, San Francisco, CA 94112
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1000 Van Ness Grand Gallery Suite
$23 SF/Yr
142,218 SF

1000 Van Ness Grand Gallery Suite

Office space • 142,218 SF

1000 Van Ness Ave, San Francisco, CA 94109
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1000 Van Ness Ave | Lobby Kiosk
$23 SF/Yr
142,218 SF

1000 Van Ness Ave | Lobby Kiosk

Office space • 142,218 SF

1000 Van Ness Ave, San Francisco, CA 94109
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Van Ness Ave Office Suite
$23 SF/Yr
142,218 SF

Van Ness Ave Office Suite

Historic building, prime location, 8,696 sq ft.

1000 Van Ness Ave, San Francisco, CA 94109
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San Francisco Creative Office Space
Contact for pricing
2,730 SF

San Francisco Creative Office Space

2,730 sq ft Creative Office, San Francisco

466 Brannan St, San Francisco, CA 94107
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Prestigious San Francisco Office Space
$22 SF/Yr
30,120 SF

Prestigious San Francisco Office Space

Class A Office Suites, Coworking, Financial District

505 Floors, San Francisco, CA 94111
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Mission Street Creative Office Space
$49 SF/Yr
44,800 SF

Mission Street Creative Office Space

San Francisco Creative Office, 5,919-6,028 SF Available

611-615 Mission St, San Francisco, CA 94105
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SOMA Creative Office Space for Lease
$24 SF/Yr
5,495 SF

SOMA Creative Office Space for Lease

Modern, renovated office in vibrant South Park

536 Bryant St, San Francisco, CA 94107
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550 California St: Premier Office Space
$36 SF/Yr
361,537 SF

550 California St: Premier Office Space

Class A Office, San Francisco's Financial District

550 California St, San Francisco, CA 94104
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Mission District Office Suite
$21 SF/Yr
1,100 SF

Mission District Office Suite

1,100 sq ft, vibrant Mission location

2729 Mission St, San Francisco, CA 94110
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Grant Avenue Office Space
Contact for pricing
7,196 SF

Grant Avenue Office Space

Prime San Francisco Office, Multiple Suites Available

231 Grant Ave, San Francisco, CA 94108
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Howard Street Office Space For Lease
Contact for pricing
3,371 SF

Howard Street Office Space For Lease

Prime San Francisco Office, 3,371 SF

1014 Howard St, San Francisco, CA 94103
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Mission & 3rd St Office Space
$22 SF/Yr
37,834 SF

Mission & 3rd St Office Space

Prime San Francisco Office Suites

95 3Rd St, San Francisco, CA 94103
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San Francisco Creative Office Space
Contact for pricing
17,138 SF

San Francisco Creative Office Space

Boutique Office Building, South Financial District, Flexible Lease Terms

111 New Montgomery St, San Francisco, CA 94105
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114 Channel St
Contact for pricing
3,629 SF

114 Channel St

Coworking space

114 Channel St, San Francisco, CA 94158
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San Francisco Office Space for Lease
$57 SF/Yr
28,302 SF

San Francisco Office Space for Lease

Prestigious Coworking & Executive Suites

580 Floors, San Francisco, CA 94104
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San Francisco Creative Office Space
$50 SF/Yr
46,263 SF

San Francisco Creative Office Space

Prime Bush Street Office Suites Available

530 Bush St, San Francisco, CA 94108
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Mason Street Creative Office Space
Contact for pricing
40,123 SF

Mason Street Creative Office Space

Historic San Francisco Office Building - Available Now

425 Mason St, San Francisco, CA 94102
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715 Bryant St: Executive Suites
$26 SF/Yr
5,934 SF

715 Bryant St: Executive Suites

San Francisco Office Space: Prime South of Market Location

715 Bryant St, San Francisco, CA 94107
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Mid-Market San Francisco Office Space
$67 SF/Yr
19,005 SF

Mid-Market San Francisco Office Space

Prestigious San Francisco office suites, flexible options.

1390 Market St, San Francisco, CA 94102
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San Francisco Waterfront Office Space
$22 SF/Yr
35,313 SF

San Francisco Waterfront Office Space

Prime San Francisco office, flexible layouts.

1160 Battery St, San Francisco, CA 94111
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Mission Street Creative Office Space
Contact for pricing
60,619 SF

Mission Street Creative Office Space

San Francisco Creative Office - 60,619 SF Available

2101 Mission St, San Francisco, CA 94110
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San Francisco, CA Office space Leasing Opportunities Market Analysis

Explore Office space leasing options in San Francisco, CA with 521 listings featured on our commercial real estate exchange. The current inventory includes 113,175,849,600 square feet of properties with an estimated lease value of $7,325 /Mo.

Estimated lease rates for Office space in San Francisco, CA begin at $1.50 SF/Yr, with an average of $35 SF/Yr and extend to $100 SF/Yr.
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